Results 161 to 170 of about 476,420 (328)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Efficient skyline query processing with user-specified conditional preference. [PDF]

PeerJ Comput Sci
Ke S, Fu X, Li J.
europepmc   +1 more source

SparkGIS: Resource Aware Efficient In-Memory Spatial Query Processing. [PDF]

Proc ACM SIGSPATIAL Int Conf Adv Inf, 2017
Baig F, Vo H, Kurc T, Saltz J, Wang F.
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

<i>F</i>u<i>n</i>Da: scalable serverless data analytics and in situ query processing. [PDF]

J Big Data
Lounissi E, Das SK, Peter R, Zhang X, Ray S, Jia L.   +5 more
europepmc   +1 more source

Private and Efficient Query Processing on Outsourced Genomic Databases. [PDF]

IEEE J Biomed Health Inform, 2017
Ghasemi R, Al Aziz MM, Mohammed N, Dehkordi MH, Jiang X.   +4 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

CSQUiD: an index and non-probability framework for constrained skyline query processing over uncertain data. [PDF]

PeerJ Comput Sci
Lawal MM, Ibrahim H, Mohd Sani NF, Yaakob R, Alwan AA.   +4 more
europepmc   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

BioFed: federated query processing over life sciences linked open data. [PDF]

J Biomed Semantics, 2017
Hasnain A, Mehmood Q, Sana E Zainab S, Saleem M, Warren C, Zehra D, Decker S, Rebholz-Schuhmann D.   +7 more
europepmc   +1 more source