Results 111 to 120 of about 1,183,543 (353)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

THE RESEARCH OF WORK MOTIVATION AS A MECHANISM TO IMPROVE THE PERSONNEL POLICY OF PUBLIC SERVANTS OF THE FEDERAL BAILIFF SERVICE

open access: yesВестник Северо-Кавказского федерального университета, 2022
Nowadays, the most pressing task is study of reasons to low motivation of the bailiffs in their performance as well as the development of measures to improve the personnel policy ofthe Public Servants of the Federal Bailiff Service.
Irina Novikova
doaj  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The monitoring of independent student work with the help of didactic maintenance

open access: yesВестник Самарского государственного технического университета. Серия: Психолого-педагогические науки, 2016
In order to improve the efficiency of independent student work a survey of first and second year students of different faculties of SamSTU was conducted. This article discusses and analyzes the results of the survey.
Irina N. Pavlova, Natalya V. Spiridonova
doaj  

QUESTIONING JAVANESE LANGUAGE VALUE AND VITALITY WITH ITS MILLIONS OF SPEAKERS [PDF]

open access: yes, 2017
Javanese holds the top rank of local language used in Indonesia for its biggest speakers noted. When many may worry about language endangerment, Javanese may not be one of them. Its high percentage usage makes people believe that this language is ‘safe’
Susilowati, Dwi
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

ANALYSIS OF IMPLEMENTATION OF ADDITIONAL EDUCATION PROGRAMMES FOR CHILDREN (AS EXEMPLIFIED BY PROGRAMMES ON PREPARATION FOR DRIVING)

open access: yesВестник Северо-Кавказского федерального университета, 2022
In the following article results of a complex analysis of implementation ofexisting academic programmes on preparation for driving in organizations for additional education of children are presented; requirements for the concept of preparation for ...
Anna Ter-Grigor'yants   +2 more
doaj  

Questioning the Entrepreneurial State

open access: yesInternational Studies in Entrepreneurship, 2022

semanticscholar   +1 more source

Teaching and Un-Teaching Source Evaluation: Questioning Authority in Information Literacy Instruction

open access: yes, 2017
This study details the design of instruction sessions for undergraduate students that intended to encourage critical source evaluation and the questioning of established authorities, and appraises these instructional aims through a thematic analysis of ...
K. Angell, Eamon Tewell
semanticscholar   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

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