Results 131 to 140 of about 1,183,543 (353)
Do carrots really have to travel 700 kilometres? [PDF]
, 2005 The transport question was a starting point for local food activities in Kauhajoki, in western Finland. Questioning this led to further activities in the area.
Kakriainen, Salla
core
Questions, questions and more questions
The Bulletin of the Royal College of Surgeons of EnglandCan we find the right answers to the problems facing the NHS?
openaire +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Questioning the existence of a unique ground state structure for Si clusters
, 2006 Density functional and quantum Monte Carlo calculations challenge the existence of a unique ground state structure for certain Si clusters. For Si clusters with more than a dozen atoms the lowest ten isomers are close in energy and for some clusters ...
Delley, B. +5 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Problematizing ‘wickedness’: a critique of the wicked problems concept, from philosophy to practice
Policy & Society, 2019 The concept of ‘wicked problems’ is a major current in the fields of policy analysis and planning. However, the basis of the concept has been insufficiently examined. This re-examination of its conceptual basis explains the origins of the limitations and
Nick Turnbull, Robert Hoppe
doaj +1 more source
Student teachers’ mathematical questioning and courage in metaphorical thinking learning
, 2018 This study was designed in the form of experiments with control group design and post-test only which aimed to examine the role of metaphorical thinking learning in the mathematical questioning ability of student teachers based on the level of ...
H. Hendriana, W. Hidayat, M. G. Ristiana
semanticscholar +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Teachers' use of questioning in supporting learners doing science investigations
South African Journal of Education, 2011 I examine how teachers employ a questioning strategy in supporting Grade 9 learners doing science investigations in South African schools. A particular focus of this study was how teachers use questioning in contributing towards the autonomy of these ...
Umesh Ramnarain
doaj