Results 141 to 150 of about 5,616,767 (291)

Metacognition and meta-metacognition for common perceptual experiences. [PDF]

J Exp Psychol Hum Percept Perform
Gao Y, Fung H, Rahnev D.
europepmc   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Assessment of LLMs on basic bioinformatics tasks requiring multi-step reasoning and code writing. [PDF]

Bioinformatics
Rajesh V, Blumberg M, Jain S, Siwo GH.
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Crafting interview questions for inclusive excellence : presentation

Workshop on creating interview questions for Oregon State University's Search Advocate Program.At the end of this session you will be prepared to: 1.
Gillies, Anne, Oregon State University
core   +2 more sources

Research Priorities for Preconception Health in Scotland: A Multidisciplinary Call to Action. [PDF]

Health Expect
Currie S, Brough EJ, Ryan L, Renwick K, Rose B, Ganguly A.   +5 more
europepmc   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Criminal procedure: LexisNexis questions and answers

, 2016
This book provides an understanding of criminal procedure, and gives a clear and systematic approach to analysing and answering problem and exam ...
Braun, Kerstin, Hemming, Andrew
core  

Development of a tool to measure patient-oriented outcomes for Veterans with inflammatory arthritis initiating self-administered biologic therapies. [PDF]

Explor Res Clin Soc Pharm
Margolis A, Nickel C, Shiyanbola O, Apitz N, Cooley G, Chewning B.   +5 more
europepmc   +1 more source