Results 151 to 160 of about 4,525,545 (359)

Predicting the Quality of Warfarin Therapy: Reframing the Question [PDF]

, 2019
Geoffrey D. Barnes
openalex   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Value of CVP: an epidemiological or physiological question? [PDF]

, 2016
Sheldon Magder
openalex   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Poétique de la question chez Raymond Queneau : le cas des jeunes filles

, 2006
Rioux, Dominique
openalex   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Insincere Questions: How to Deceive With Interrogatives

Studia Semiotyczne
This paper investigates how interrogative sentences, typically not regarded as a means of lying, can nonetheless be used to deceive and mislead. While most definitions of lying restrict it to assertions, questions can subtly lead listeners to adopt ...
Tomasz Puczyłowski
doaj  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Frequently Asked Questions: Stem Cells

, 2010
Kirstin Matthews, fellow in science and technology, answers questions regarding the biology, practical uses and ethical dilemmas surrounding stem ...
Matthews, Kirstin R.W.
core  

Public, non-public : questions de méthodologie

, 2017
Centre de recherche sur les médiations Communication, langue, art, culture (EA 3476, Université de Lorraine, France) ¿ Interrogations ?, 24, 2017 Public, non-public : questions de ...
Angeliki Koukoutsaki-Monnier
core   +1 more source