Results 1 to 10 of about 37,897 (253)
Variants in COMT, CYP3A5, CYP2B6, and ABCG2 Alter Quetiapine Pharmacokinetics
Pharmaceutics, 2021 Quetiapine is an atypical antipsychotic widely used for the treatment of schizophrenia and the depressive episodes of bipolar disorder. The aim of this work was to investigate the effect of variants in relevant pharmacogenes in the pharmacokinetics of ...
Pablo Zubiaur +8 more
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Association of Low-Dose Quetiapine and Diabetes [PDF]
JAMA Network Open, 2021 Key Points Question Is the use of quetiapine in low doses associated with increased risk of diabetes? Findings In this nationwide cohort study that included 57 701 new users of quetiapine in low doses and without severe mental illness, the incidence of ...
Mikkel Højlund +4 more
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Post‐therapy plasma concentrations of quetiapine in Taiwanese patients [PDF]
Neuropsychopharmacology Reports, 2023 Aims Quetiapine is widely used to treat psychiatric disorders such as major depression, generalized anxiety disorder, dysthymic disorder, and insomnia other than schizophrenia and bipolar disorder.
Cho‐Yin Huang +3 more
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Quetiapine and other antipsychotics combined with opioids in legal autopsy cases: A random finding or cause of fatal outcome? [PDF]
Basic & Clinical Pharmacology & Toxicology, 2020 Opioid poisoning is a frequent cause of death in drug addicts and occurs with opioid treatment. Quetiapine is often found in forensic autopsies and may increase the risk of fatal opioid poisoning by enhancing sedation, respiratory depression, hypotension
Freja Drost Andersen +2 more
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Evaluation the inhibitory effect of nicardipine on the metabolism of quetiapine [PDF]
Frontiers in PharmacologyThe aim of this study was to investigate the impact of calcium channel blockers (CCBs) and antihypertensive traditional Chinese medicine (TCM) on the metabolism of quetiapine. In vitro, two incubation systems of rat liver microsomes (RLM) and human liver
Jinzhao Yang +5 more
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Substance Abuse: Research and Treatment, 2019 Background: Second-generation antipsychotics (SGAs) are assumed to have little abuse potential. However, reports of quetiapine abuse have emerged as prescribing has increased in recent years.
Kirk E Evoy +6 more
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Frontiers in Psychiatry, 2020 Epigenetic alterations and impaired oligodendroglial myelination in the prefrontal cortex have been shown to correlate with behavioral and cognitive dysfunctions in social deprivation.
Xianjun Chen +10 more
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Quetiapine misuse and abuse: Is it an atypical paradigm of drug seeking behavior?
Journal of Research in Pharmacy Practice, 2017 Recent case reports in medical literatures suggest that more and more second-generation atypical antipsychotics (AAs) have been prescribed for off-label use; quetiapine (Brand name: Seroquel®) showed increase in its trend for off-label use.
Sean Kim +4 more
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Indian Journal of Ophthalmology, 2019 A 30-year-old insomniac, an off-label user of quetiapine, presented with blurring of central vision, eventually diagnosed as central serous chorioretinopathy.
Manish Jain
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Química Nova, 2015 Quetiapine is an atypical antipsychotic used to treat schizophrenia. However, despite great interest for its chronic therapeutic use, quetiapine has some important side effects such as weight gain induction.
Fernando Carreño +4 more
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