Results 221 to 230 of about 37,897 (253)

A failed 6-week,randomized, double-blind, placebo-controlled study of once-daily extended release quetiapine fumarate in patients with acute schizophrenia: lessons learned.

Psychopharmacology bulletin
OBJECTIVE To demonstrate the efficacy of once-daily extended release quetiapine fumarate (quetiapine XR) versus placebo in adults with acute exacerbation of schizophrenia. METHODS A 6-week, double-blind, randomized, placebo-controlled study. In- or out-
A. Cutler, T. Tran-Johnson, A. Kalali, M. Åström, M. Brecher, D. Meulien   +5 more
semanticscholar   +1 more source

Severe quetiapine voluntary overdose successfully treated with a new hemoperfusion sorbent

International Journal of Artificial Organs, 2019
Quetiapine overdose, although rare, is mainly linked with tachycardia, QTc-interval prolongation, somnolence, coma, hyperglycemia, and eventually hepatotoxicity and myocarditis.
L. Giuntoli, V. Dalmastri, N. Cilloni, C. Orsi, Lucia Stalteri, Valentina Demelas, G. Giuliani, G. Gordini, F. De Ponti, G. La Manna   +9 more
semanticscholar   +1 more source

Quetiapine

Reactions Weekly, 2023
  +6 more sources

Impact of Quetiapine Therapy on QTc Prolongation in Critically Ill Patients

The Annals of Pharmacotherapy, 2019
Background: Quetiapine is an atypical antipsychotic commonly utilized for the management of delirium in critically ill patients. The impact of quetiapine on QTc in the critically ill population is largely unknown. Objective: The purpose of this study was
S. Lee, Amanda A. Morris, Sarah Kim, Fanny Li, Laura Baumgartner   +4 more
semanticscholar   +1 more source

Quetiapine protects the blood-brain barrier in traumatic brain injury

Journal of Trauma and Acute Care Surgery, 2018
BACKGROUND The integrity of the blood-brain barrier (BBB) is paramount in limiting vasogenic edema following traumatic brain injury (TBI). The purpose of this study was to ascertain if quetiapine, an atypical antipsychotic commonly used in trauma ...
B. Robinson, C. Isbell, Chinchusha Anasooya Shaji, S. Kurek, Justin L Regner, B. Tharakan   +5 more
semanticscholar   +1 more source

Solid Lipid Nanoparticles Approach for Lymphatic Targeting Through Intraduodenal Delivery of Quetiapine Fumarate.

Current Drug Delivery, 2017
BACKGROUND Lymphatic route is one of the prominent routes for improving the poor bioavailability of the drugs which undergo extensive hepatic first pass metabolism. Nanocarriers (solid lipid nanoparticles) offer a new drug delivery system that could hold
Mohd Yasir, P. Gaur, Dinesh Puri, Preeti Shehkar, Shanmugam Sadish Kumar   +4 more
semanticscholar   +1 more source

Quetiapine

Reactions Weekly, 2010
  +6 more sources

A Pilot Study of the Effectiveness of Lithium Versus Quetiapine Immediate Release Monotherapy in Patients With Bipolar Spectrum Disorders

Journal of Clinical Psychopharmacology, 2018
Objective The aim of this study was to compare the effectiveness of lithium versus quetiapine immediate release (IR) monotherapy in patients with bipolar I, II, or subthreshold bipolar disorder at any phase.
K. Gao, Toyomi Goto, C. Yuan, Brittany Brownrigg, Carla M Conroy, Philip K. Chan, Mary Beth Serrano, S. Ganocy, F. Fang, J. Calabrese   +9 more
semanticscholar   +1 more source

Chronic administration of quetiapine attenuates the phencyclidine-induced recognition memory impairment and hippocampal oxidative stress in rats

NeuroReport, 2018
The underlying mechanism of atypical antipsychotics in treating cognitive impairment in schizophrenia is unclear. The aim of the present study was to evaluate the effects of quetiapine, an atypical antipsychotic drug, on object recognition memory and ...
Jue He, Fan Liu, Q. Zu, Zhizhong Xu, Hui-Fei Zheng, Xinmin Li, Wenqiang Wang   +6 more
semanticscholar   +1 more source

Quetiapine

Reactions Weekly, 2017
  +5 more sources