Results 41 to 50 of about 37,897 (253)

Inappropriate quetiapine use at a large academic medical center: frequency of misuse and associated costs of adverse effects

open access: yesTherapeutic Advances in Drug Safety, 2023
Background: Quetiapine is an antipsychotic with dose-related receptor affinity, which is commonly prescribed by specialties outside of psychiatry. Quetiapine can have adverse effects including weight gain, hyperglycemia, and falls.
Winter Roth   +2 more
doaj   +1 more source

The atypical antipsychotic quetiapine induces hyperlipidemia by activating intestinal PXR signaling.

open access: yesJCI Insight, 2019
Quetiapine, one of the most prescribed atypical antipsychotics, has been associated with hyperlipidemia and an increased risk for cardiovascular disease in patients, but the underlying mechanisms remain unknown. Here, we identified quetiapine as a potent
Zhaojie Meng   +5 more
semanticscholar   +1 more source

Effect of Peer Comparison Letters for High-Volume Primary Care Prescribers of Quetiapine in Older and Disabled Adults: A Randomized Clinical Trial

open access: yesJAMA psychiatry, 2018
Importance Antipsychotic agents, such as quetiapine fumarate, are frequently overprescribed for indications not supported by clinical evidence, potentially causing harm.
Adam Sacarny   +5 more
semanticscholar   +1 more source

Electrocardiographic changes and clinical outcomes in quetiapine poisoning: a retrospective cohort study

open access: yesToxicology Communications
Introduction Quetiapine has a three-ringed chemical structure similar to that of tricyclic antidepressants (TCA). Several electrocardiogram (ECG) findings, including prolonged QRS intervals, high R wave amplitude (tall RaVR), large R-wave/S-wave ratio ...
Fumiya Inoue   +5 more
doaj   +1 more source

Lurasidone versus Quetiapine for Cognitive Impairments in Young Patients with Bipolar Depression: A Randomized, Controlled Study

open access: yesPharmaceuticals, 2022
The clinical efficacy of lurasidone and quetiapine, two commonly prescribed atypical antipsychotics for bipolar depression, has been inadequately studied in young patients. In this randomized and controlled study, we aimed to compare the effects of these
Xiangyuan Diao   +9 more
doaj   +1 more source

Psychoactive prescription drug use and misuse in patients on opioid agonist treatment

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims To identify the patterns and trends in prescription drug use and misuse in patients on opioid agonist treatment. Methods We used data from the OPPIDUM programme, which collects data from patients attending substance abuse treatment facilities. Data collected include use of psychoactive prescription drugs in the past week.
Thomas Soeiro   +5 more
wiley   +1 more source

Clinical pharmacology consultations and their implementation in clinical decision making

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims One of the key roles of clinical pharmacologists is to work as consultants for other medical specialties. We wanted to investigate the characteristics of clinical pharmacology consultations, compare the types of consultations from different specialties, and evaluate how well the recommendations given were followed.
Mirjam Kauppila   +2 more
wiley   +1 more source

Intensive Care Management of a Case of Cardiac Arrest Following Ketiapine Use

open access: yesTürk Yoğun Bakim Derneği Dergisi, 2012
Quetiapine is an antipsychotic commonly used in treatment of depression, bipolar disorders and schizophrenia. Quetiapine interacts with several receptors present in the central nervous system and therefore may cause diverse side effects like somnolence ...
Ahmet Şen   +3 more
doaj   +1 more source

Systematic Literature Review of Quetiapine for the Treatment of Psychosis in Patients With Parkinsonism.

open access: yesThe Journal of Neuropsychiatry and Clinical Neurosciences, 2019
OBJECTIVE: The purpose of this article was to determine the efficacy and tolerability of quetiapine compared with placebo or other interventions for psychosis in parkinsonism.
Jack J. Chen   +6 more
semanticscholar   +1 more source

Drug poisonings following bariatric surgery: Case series report

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Bariatric surgery alters gastrointestinal anatomy and physiology, which likely impacts upon oral medication absorption. Drug‐ and alcohol‐related deaths in this population are being increasingly reported; however, toxicological detail is lacking. Using data reported to the National Programme on Substance Use Mortality, we identified 18 deaths in people
Eman Mshari   +3 more
wiley   +1 more source

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