Results 101 to 110 of about 38,240 (235)

Novel pH‐Responsive Structural Rearrangement of Myristic Acid‐Conjugated Quetiapine Nanosuspension for Enhanced Long‐Acting Delivery Performance

Advanced Science, Volume 11, Issue 40, October 28, 2024.
This study investigates in vitro and in vivo performance of a pH‐responsive nanosuspension of quetiapine myristate (QMN) as a novel long‐acting injectable. QMN offers simple formulation design and innovative release mechanism that can address challenges associated with polymeric systems, providing high drug content, high stability, low toxicity, and ...
Hy Dinh Nguyen, Hai Van Ngo, Beom‐Jin Lee   +2 more
wiley   +1 more source

Consensus on the pharmacological treatment of acute stress disorder in Chinese pilots: a Delphi study

BMC Psychiatry, 2023
Background Appropriate medication is very important for pilots with acute stress disorder. Improper medication can not only affect the physical and mental health of the pilots but can also endanger flight safety.
Xing Gao, Zhenzhen Wang, Li Guo, Yanan Gu, Lei Song, Zhongying Wu, Fengzhan Li, Yinchuan Jin, Qun Yang   +8 more
doaj   +1 more source

Efficacy and Safety of Transcranial Direct Current Stimulation as an Add‐On Trial Treatment for Acute Bipolar Depression Patients With Suicidal Ideation

CNS Neuroscience &Therapeutics, Volume 30, Issue 10, October 2024.
Active tDCS was superior than sham control in decreasing BSSI score, and this rapid antisuicide effect of active tDCS was revealed within 3‐day time window. ABSTRACT Aims Bipolar depression poses an overwhelming suicide risk. We aimed to examine the efficacy and safety of transcranial direct current stimulation (tDCS) combined with quetiapine in ...
Dandan Wang, Xiaonan Guo, Qi Huang, Zhong Wang, Jingkai Chen, Shaohua Hu   +5 more
wiley   +1 more source

Quetiapine versus Haloperidol in Controlling Conversion Disorder Symptoms; a Randomized Clinical Trial

Emergency, 2017
Introduction: About 5% of visits to emergency departments are made up of conversion disorder cases. This study was designed with the aim of comparing the effectiveness of quetiapine and haloperidol in controlling conversion disorder symptoms.
Saeed Reza Ghanbarizadeh, Hossein Dinpanah, Reza Ghasemi, Yaser Salahshour, Samaneh Sardashti, Mostafa Kamali, Seyed Reza Khatibi   +6 more
doaj   +1 more source

High-flow continuous hemodiafiltration successfully decreased blood pregabalin levels in a patient with severe pregabalin intoxication: a case report

Renal Replacement Therapy, 2022
Background Severe pregabalin intoxication may cause serious symptoms, such as coma. Since pregabalin is a small molecule with no protein binding sites and has low volume of distribution, hemodialysis can be effective in eliminating pregabalin from the ...
Takashi Shimazui, Nobuya Kitamura, Kuniyuki Kako, Shinya Iwase, Toshinao Suzuki, Shota Hoshino, Hiromi Futagami, Kazuhiko Kibayashi, Ken-ichiro Nakao   +8 more
doaj   +1 more source

Clinical pharmacology considerations and drug–drug interactions with long‐acting cabotegravir and rilpivirine relevant to sub‐Saharan Africa

British Journal of Clinical Pharmacology, Volume 90, Issue 9, Page 2079-2091, September 2024.
Long‐acting injectable (LAI) cabotegravir and rilpivirine for HIV treatment and LAI cabotegravir for pre‐exposure HIV prophylaxis are being rolled out in a multitude of countries worldwide. Due to the prolonged exposure, it can be challenging to undertake ‘traditional’ pharmacokinetic studies and current guidance is derived from their oral equivalents ...
Adrian Steulet, Bonniface Obura, Catriona Waitt, Eva Laker, Melanie R. Nicol, Fiona V. Cresswell   +5 more
wiley   +1 more source

Design and Evaluation of a Novel Gas Formation-Based Multiple-Unit Gastro-Retentive Floating Drug Delivery System for Quetiapine Fumarate [PDF]

, 2014
Purpose: To develop a gastro-retentive formulation of quetiapine fumarate in the form of floating minitablets.Methods: The system consisted of core units prepared by direct  compression process, which were coated with three successive layers, namely, an ...
Katakam, VK, Panakanti, PK, Reddy, S, Yamsani, MR   +3 more
core   +2 more sources

Effects of once-daily extended release quetiapine fumarate on patient-reported outcomes in patients with generalized anxiety disorder

Neuropsychiatric Disease and Treatment, 2012
Jean Endicott,1 Henrik Svedsäter,2 Julie C Locklear21Department of Psychiatry, Columbia University, New York, NY; 2AstraZeneca Pharmaceuticals, Wilmington, DE, USABackground: We evaluated the effects of once-daily extended-release quetiapine ...
Endicott J, Svedsäter H, Locklear JC   +2 more
doaj  

TITRIMETRIC AND SENSITIVE SPECTRO-PHOTOMETRIC METHODS FOR THE ASSAY OF QUETIAPINE FUMARATE IN PHARMACEUTICAL FORMULATIONS [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2011
Quetiapine fumarate (QTF) is a selective monoaminergic antagonist with high affinity for the serotonin Type 2 (5HT2), and dopamine type 2 (D2) receptors.
Nagaraju Rajendraprasad, Pavagada Jagannathamurthy Ramesh, Hosakere Oddarevanna Revanasiddappa, Kanakapura Basavaiah Vinay   +3 more
doaj  

Toxicological and ecotoxicological risk‐based prioritization of pharmaceuticals in the natural environment [PDF]

, 2016
Approximately 1500 active pharmaceutical ingredients are currently in use; however, the environmental occurrence and impacts of only a small proportion of these have been investigated.
Agerstrand, Ashton, Boxall, Boxall, Capleton, Carter, Cooper, Crane, Dong, Drillia, Escher, Fick, Franco, Fu, Halling-Sorensen, Hirsch, Kidd, Kim, Kolpin, Kostich, Lahnsteiner, Laville, Monteiro, Niemuth, Ramirez, Roberts, Rocco, Roos, Sanderson, Santos, Schwab, Schwaiger, Sinclair, Triebskorn, Triebskorn, Wang, Webb, Zha   +37 more
core   +1 more source