PREPARATION AND EVALUATION OF QUETIAPINE FUMARATE MICROEMULSIONS: A NOVEL DELIVERY SYSTEM [PDF]
Objective: In the present study, the main objective is to improve solubility and bioavailability of Quetiapine fumarate by formulation into micro emulsion.
Parvathi, M. +3 more
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Therapeutic and toxic blood concentrations of nearly 1,000 drugs and other xenobiotics [PDF]
Introduction: In order to assess the significance of drug levels measured in intensive care medicine, clinical and forensic toxicology, as well as for therapeutic drug monitoring, it is essential that a comprehensive collection of data is readily ...
Andresen, Hilke +3 more
core +1 more source
The frequency of epileptic seizures during therapy with antipsychotics and placebo within randomized-controlled trials [PDF]
Die vorliegende Arbeit untersucht die Auftretenshäufigkeit epileptischer Anfälle als schwere unerwünschte Wirkung („serious adverse events“) während der Therapie mit Antipsychotika der zweiten Generation im Rahmen randomisierter placebo-kontrollierter ...
Reichelt, Leonie Isabelle
core
Development and Validation of a Stability Indicating RP-UPLC Method for Determination of Quetiapine in Pharmaceutical Dosage Form [PDF]
The present work reports a stability indicating reversed phase ultra performance liquid chromatography (RP-UPLC) method for the quantitative determination of quetiapine in pharmaceutical dosage form.
Patel, Mukesh C. +1 more
core +2 more sources
Faktor yang Berhubungan dengan Kasus Skizofrenia pada Pasien Rawat Inap Rumah Sakit Khusus Jiwa Soeprapto Provinsi Bengkulu [PDF]
The purpose of this study was to determine the factors associated with the incidence of schizophrenia in patients in the Inpatient Room of Soeprapto Special Base Hospital of Bengkulu Province.The method used is descriptive research design with cross ...
Harahap, R. M. (Resnia) +1 more
core +2 more sources
Alcohol use disorders: harmful drinking and alcohol dependence now available. [PDF]
A summary of selected new evidence relevant to NICE clinical guideline 115 ‘Alcohol use disorders: diagnosis, assessment and management of harmful drinking and alcohol dependence’ (2011)
core
Background: Adverse drug reactions (ADRs) are a major cause of hospital admissions, prolonged hospital stays, morbidity, and drug-related mortality. In this study, we sought to identify the most frequently reported medications and associated side effects
Andy R. Eugene, Beata Eugene
doaj +1 more source
Extended-release quetiapine fumarate in the treatment of bipolar disorder
The management of bipolar disorder presents challenges for the clinician who is often required to prescribe a variety of medication regimes for the different phases of the illness. With a range of pharmacological actions, quetiapine fumarate is a useful option in such circumstances.
Rajiv Weerasundera, David J Castle
openaire +1 more source
PREPARATION AND SOLID STATE CHARACTERIZATION OF NANOCRYSTALS FOR SOLUBILITY ENHANCEMENT OF QUETIAPINE FUMARATE [PDF]
Objective: Quetiapine fumarate (QF) has poor water solubility and its oral bioavailability is observed to be 9% [1]. The objective of the present work is to prepare QF nanoparticles by wet media milling (WMM) and explore on the improvement in solubility ...
Arutla, Srinivas +2 more
core +1 more source
Quetiapine N-oxide–fumaric acid (2/1)
The title compound (systematic name: 2-{2-[4-(dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl 1-oxide]ethoxy}ethanol–fumaric acid (2/1)), C21H25N3O3S·0.5C4H4O4, is one of the oxidation products of quetiapine hemifumaric acid. In the tricyclic fragment, the central thiazepine ring displays a boat conformation and the benzene rings are
Jin Shen +4 more
openaire +1 more source

