Results 81 to 90 of about 38,240 (235)

Organoid Models to Study Human Infectious Diseases

Cell Proliferation, Volume 58, Issue 11, November 2025.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu, Dan Chen, Xinzhi Yang, Liuliu Yang, Yuling Han   +4 more
wiley   +1 more source

Investigating and Resolving Cardiotoxicity Induced by COVID‐19 Treatments using Human Pluripotent Stem Cell‐Derived Cardiomyocytes and Engineered Heart Tissues

Advanced Science, 2022
Coronavirus disease 2019 continues to spread worldwide. Given the urgent need for effective treatments, many clinical trials are ongoing through repurposing approved drugs.
He Xu, Ge Liu, Jixing Gong, Ying Zhang, Shanshan Gu, Zhongjun Wan, Pengcheng Yang, Yage Nie, Yinghan Wang, Zhan‐peng Huang, Guanzheng Luo, Zhongyan Chen, Donghui Zhang, Nan Cao   +13 more
doaj   +1 more source

Formulation and Evaluation of Immediate-Release Quetiapine Fumarate Tablets Via Twin-Screw Melt Granulation

Journal of Pharmaceutical Innovation
This study aimed to develop immediate-release Quetiapine Fumarate (QTF) tablets using twin-screw melt granulation (TSMG), a solvent-free and efficient granulation method, and compare their dissolution profiles with the marketed product.
Salonee Chavan, S. Munnangi, Nagarjuna Narala, S. Vemula, Michael A. Repka   +4 more
semanticscholar   +1 more source

Recent Advances in Interventions Targeting Remyelination and a Systematic Review of Remyelinating Effects of Approved Disease‐Modifying Treatments for Multiple Sclerosis

European Journal of Neurology, Volume 32, Issue 11, November 2025.
ABSTRACT Background Regenerative strategies in progressive multiple sclerosis (MS) pose a significant unmet need. Combining immunomodulatory treatment with remyelinating interventions to target the complex underlying pathogenesis appeals as the next frontier in MS therapeutic developments.
Anna‐Victoria De Keersmaecker, Eline van Doninck, Inez Wens, Yousra El Ouaamari, Veronica Popescu, Guy Laureys, Melissa Cambron, Miguel D'Haeseleer, Lander Willem, Judith Derdelinckx, Tatjana Reynders, Barbara Willekens   +11 more
wiley   +1 more source

Lurasidone for the treatment of bipolar depression: an evidence-based review [PDF]

, 2015
Bipolar disorder (BD) is a debilitating and difficult-to-treat psychiatric disease that presents a serious burden to patients’ lives as well as health care systems around the world.
Corse, Andrew, Deckersbach, Thilo, Franklin, Rachel, Widge, Alik, Zorowitz, Sam   +4 more
core   +1 more source

Development of determination methods of quetiapine fumarate for forensic-pharmaceutical purposes

ScienceRise: Pharmaceutical Science, 2021
Quetiapine fumarate (an antipsychotic) is part of numerous generic drugs that are in fairly wide demand among the population, therefore, more and more data appear on the counterfeiting and smuggling of funds, as well as non-medical use, which are life ...
O. Bevz, I. Sych, A. Shaposhnyk, I. Sych, O. Kryvanych, S. Taran, L. Perekhoda   +6 more
semanticscholar   +1 more source

Is Hearing Impairment Associated With Specific Behavioural and Psychological Symptoms of Dementia in Japanese Older Adults Attending a Memory Clinic?

Psychogeriatrics, Volume 25, Issue 5, September 2025.
ABSTRACT Background Behavioural and psychological symptoms of dementia (BPSD), encompassing disturbances in perception, thought, mood and behaviour, are prevalent among individuals with dementia and can substantially affect their quality of life. Although prior research has suggested that hearing impairment (HI) may exacerbate BPSD due to communication
Saki Tanaka, Ryo Katayose, Teruaki Kawasaki, Ichiro Akiguchi, Mihoko Ogita   +4 more
wiley   +1 more source

Self-harm, Unintentional Injury, and Suicide in Bipolar Disorder During Maintenance Mood Stabilizer Treatment: A UK Population-Based Electronic Health Records Study [PDF]

, 2016
Importance: Self-harm is a prominent cause of morbidity in patients with bipolar disorder and is strongly associated with suicide. There is evolving evidence that lithium use may reduce suicidal behavior, in addition to concerns that the use of ...
Geddes, JR, Hayes, JF, King, M, Marston, L, Osborn, DP, Pitman, A, Walters, K   +6 more
core  

Trends in resource utilization for new‐onset psychosis hospitalizations at children's hospitals

Journal of Hospital Medicine, Volume 20, Issue 7, Page 710-726, July 2025.
Abstract Background Children with new‐onset psychosis often require hospitalization for medical evaluation. Objectives The goal of this study was to assess variations in the management of children with new‐onset psychosis and characterize trends in resource utilization.
Ankita Gupta, Matt Hall, Benjamin Masserano, Averi Wilson, Katherine Johnson, Clifford Chen, Lasya Challa, Harita Katragadda, Vineeta Mittal   +8 more
wiley   +1 more source

Terapia farmacologica e suicidio: l’esperienza del Gabapentin e della Quetiapina. Considerazioni medico-legali basate su una meta-analisi [PDF]

, 2012
Riassunto Il Gabapentin e la Quetiapina sono due farmaci appartenenti a due categorie farmaceutiche diverse e presentano diverse indicazioni terapeutiche.
Massoni, Francesco, Mastronardi, Vincenzo, Ricci, Serafino, Simeone, Claudio   +3 more
core