Results 141 to 150 of about 246,131 (378)

Enhancing Sensitivity across Scales with Highly Sensitive Hall Effect‐Based Auxetic Tactile Sensors

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Herein, a tactile sensor based on hall‐effect sensors with an auxetic structure, called Hall effect‐based auxetic tactile sensor (HEATS), is proposed. The change in magnetism resulting from the deformation of the auxetic structure is utilized for sensing.
Youngheon Yun   +6 more
wiley   +1 more source

Struktureller Mechanismus eines Aktivitäts‐Photoschalters am β2‐adrenergen Rezeptor

open access: yesAngewandte Chemie, EarlyView.
Zeitaufgelöste Strukturen aus Messungen an Röntgen‐Freie‐Elektronen‐Lasern in Kombination mit zellulären Assays zeigen, wie der photoschaltbare β‐Blocker Photoazolol‐1 als Wirksamkeits‐Photoschalter der Funktion des β2‐adrenergen Rezeptor wirkt. Die lichtinduzierte Neupositionierung des Liganden verschiebt die Aktivität von inversem Agonistimus hin zu ...
Robin Stipp   +29 more
wiley   +1 more source

Proteinvermittelte Kupfer‐Redoxregulation: Rolle von Disulfidbrücken und allosterischer Modulation

open access: yesAngewandte Chemie, EarlyView.
Copper binding triggers structural changes that expose a reactive disulphide bridge, enabling intrinsic Cu(II) reduction in folded proteins. SAXS, XAS, and QM/MM simulations reveal how globular proteins such as HSA and SOD1 employ disulphide‐mediated dynamics to modulate site accessibility and control copper redox chemistry.
Rebecca Sternke‐Hoffmann   +9 more
wiley   +1 more source

The Sugarcane genome sequencing effort: An overview of the strategy, goals and existing data : [Abstract W538] [PDF]

open access: yes, 2010
Sugarcane is a major feedstock used for biofuel production worldwide. Sugarcane cultivars (Saccharum spp) are derived from interspecific hybridization obtained a century ago by crossing Saccharum officinarum (2n=8x=80) and S.
D'Hont, Angélique   +5 more
core  

CLINICAL PHARMACY, PHARMACEUTICAL CARE: CONCEPTS, PHILOSOPHY, PROFESSIONAL PRACTICE AND ITS APPLICATION TO THE COLOMBIAN CONTEXT

open access: yesVitae, 2012
Pharmaceutical care is a healthcare practice that has been implemented recently worldwide. Its aim is the rational medication use and the achievement of desired therapeutic goals that improve the patient quality of life.
Andrea SALAZAR-OSPINA   +3 more
doaj  

Foliar Architecture and caulinar morpho-anatomy of Zuccagnia Punctata (Fabaceae). Histolocalization of bioactive compounds [PDF]

open access: yes, 2013
Zuccagnia punctata Cav. (Fabaceae, Caesalpinioideae), comúnmente denominada jarilla macho, es una especie endémica de Argentina, característica de la flora xerófila de la Provincia Biogeográfica del Monte.
Cuello, Ana Soledad   +6 more
core  

PARFOR QUIMICA

open access: yes, 2018
O presente trabalho buscou identificar e discutir alguns aspectos explorados nas aulas de Libras e suas implicações para o ensino e a aprendizagem de Química haja vista o material digital produzido por Benassi e Duarte (2016). Assim optou-se pela abordagem qualitativa, alinhada à técnica de Análise de Conteúdo, tendo como base os estudos de Silveira ...
openaire   +1 more source

Structural Mechanism of an Efficacy Photoswitch Targeting the β2‐adrenergic Receptor

open access: yesAngewandte Chemie International Edition, EarlyView.
Time‐resolved structures from x‐ray free‐electron laser measurements combined with cellular assays demonstrate how the photoswitchable β‐blocker photoazolol‐1 acts as an efficacy switch of β2‐adrenergic receptor function. Light‐induced ligand repositioning shifts activity from inverse agonism toward neutral antagonism by altering local helical ...
Robin Stipp   +29 more
wiley   +1 more source

Protein‐Driven Copper Redox Regulation: Uncovering the Role of Disulphide Bonds and Allosteric Modulation

open access: yesAngewandte Chemie International Edition, EarlyView.
Copper binding triggers structural changes that expose a reactive disulphide bridge, enabling intrinsic Cu(II) reduction in folded proteins. SAXS, XAS, and QM/MM simulations reveal how globular proteins such as HSA and SOD1 employ disulphide‐mediated dynamics to modulate site accessibility and control copper redox chemistry.
Rebecca Sternke‐Hoffmann   +9 more
wiley   +1 more source

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