Results 181 to 190 of about 91,095 (298)

Acute Modafinil Exposure Induces Neurobehavioral Alterations in Zebrafish: Implications for Off‐Label Cognitive Enhancement

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Modafinil (2‐(benzhydrylsulfinyl)acetamide) is a psychostimulant commonly prescribed for sleep disorders such as narcolepsy, excessive daytime sleepiness, and obstructive sleep apnea. Recently, its use has extended beyond clinical indications, with neurotypical individuals adopting it as a smart drug to enhance alertness and cognitive ...
Luciane Dellazari da Silva do Prado   +9 more
wiley   +1 more source

Biological Effects of Selenium‐Containing Ionic Liquids: Cytotoxicity, Mercury Interaction, and Antiproliferative Activity in Glioblastoma Cells

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Selenium (Se) is an essential micronutrient that participates in redox regulation and cellular homeostasis. Selenium‐containing ionic liquids (ILsSe) have emerged as hybrid compounds combining the properties of organoselenium molecules with the tunable features of ionic liquids.
Guilherme Schmitt Rieder   +17 more
wiley   +1 more source

Cardiac Histomorphometric Implications Resulting From Chronic Nandrolone Decanoate Treatment in Rats Subjected to Resistance Training

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT The effects of anabolic steroid abuse on the cardiac tissue of resistance training practitioners are poorly understood. Herein, we present the histomorphometric implications of resistance training in rats treated with nandrolone decanoate, an androgenic anabolic steroid. Eighteen‐week‐old male Wistar rats (N = 32) were divided into two groups (
Lucas D. Ferreira   +6 more
wiley   +1 more source

Production of recombinant human granulocyte‐macrophage colony‐stimulating factor in thermoinducible E. coli: Tuning inclusion body architecture and protein yield via dissolved oxygen control

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Recombinant protein expression in Escherichia coli frequently results in the formation of inclusion bodies (IBs), which provide high protein accumulation but often require additional steps to recover functional protein. Although culture conditions strongly influence IB physicochemical and structural characteristics, the impact of ...
Ximena Gómez‐Gil   +7 more
wiley   +1 more source

A pd‐Catalyzed Three‐Component Approach for the Synthesis of Monomeric and Dimeric Tetrahydro‐4H‐Furo[2,3‐b]Chromene Steroids

open access: yesJournal of Heterocyclic Chemistry, EarlyView.
The three‐component reaction of a steroid bearing a dihydrofuran ring, with methyl orthoformate and salicylaldehyde produced chromanketals. ABSTRACT The three‐component reaction of a steroid bearing a dihydrofuran ring, with methyl orthoformate and salicylaldehyde produced chromanketals through a [4 + 2] inverse electron demand cycloaddition ...
Juan E. Hernández‐Martínez   +5 more
wiley   +1 more source

Optimizing germination and cultivation of edible halophytes using effluents from an IMTA system

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Halophytes offer nature‐based solutions to food insecurity and soil degradation, while their integration into integrated multi‐trophic aquaculture (IMTA) systems promotes circular economy practices. This study aimed to optimize the germination and cultivation of edible halophytic species, namely Limbarda crithmoides, Suaeda vera and
Viana Castañeda‐Loaiza   +5 more
wiley   +1 more source

Composition and functionalities of peanut protein concentrates using ethanol as a defatted solvent and a precipitating agent

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Defatted solids (DSs) from vegetable oil extraction represent valuable feedstocks for producing protein concentrates with tailored functional properties. In the present study, using peanut protein concentrates obtained from press cakes defatted with ethanol (DSEt) or hexane (DSHx), we aimed to evaluate ethanol as a green solvent for
Paloma Jamily Cristina Magalhães   +8 more
wiley   +1 more source

Use of predictive tools for the analysis of bioactive compounds in Crocus sativus L. flowers

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Crocus sativus L. (saffron) flowers have high bioactive potential because of their content of crocins, safranal and phenolic compounds. The development of predictive models based on near‐infrared (NIR) spectroscopy and partial least squares regression to estimate the antioxidant capacity of saffron flower, evaluated using oxygen ...
Manuel Piqueras‐García   +4 more
wiley   +1 more source

Antimicrobial bilayer starch film containing zein electrospun fibers encapsulating thyme essential oil for cherry tomato packaging

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Background This study evaluated the antimicrobial activity of thyme essential oil (TEO) encapsulated in electrospun zein fibers for use in bilayer films as active packaging for cherry tomatoes. The antimicrobial activity of TEO and bilayer films with 20%, 40%, and 60% TEO was assessed with agar diffusion and microatmosphere assays.
Jéssica Silveira Vitoria   +7 more
wiley   +1 more source

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