El objetivo del presente estudio fue evaluar la respuesta histológica tumoral luego de quimioterapia neoadyuvante (QNA) en adenocarcinoma gástrico avanzado. Se realizó un estudio analítico observacional de corte transversal en base a datos registrados en las historias clínicas de pacientes con diagnóstico de adenocarcinoma gástrico avanzado tratados ...
Ana K. Zegarra-Castillo +3 more
openaire +2 more sources
Quimioterapia neoadyuvante en cáncer de mama, localmente avanzado
Introducción: el cáncer de mama es actualmente el tumor maligno más frecuente en la mujer y la quimioterapia constituye una de las principales armas terapéuticas en este padecimiento. Objetivo: caracterizar el comportamiento de los enfermos con cáncer de mama localmente avanzado, que recibieron tratamiento con quimioterapia neoadyuvante.
Alexander Portelles Cruz +4 more
openaire +2 more sources
Supervivencia de cáncer de mama tratado con quimioterapia neoadyuvante.
Objetivo: evaluar la sobrevida global y libre de enfermedad en mujeres con cáncer de mama que reciben tratamiento de quimioterapia neoadyuvante en la clínica Oncocare durante el período de 2005 a 2014. Métodos: este estudio involucró el análisis de información en el período comprendido entre el 1º de enero de 2005 y el 31 diciembre de 2014.
Pedro Luis Ramos Guette +4 more
openaire +3 more sources
Propensity score regression analysis of oesophageal adenocarcinoma treatment with surgery alone or neoadjuvant chemotherapy [PDF]
Following propensity adjustment for stage, age and sex, neoadjuvant therapy was not associated with survival. Tumour regression is a powerful prognostic indicator, and future research should focus on identifying patients who will derive the most benefit from neoadjuvant chemotherapy.
A. G. M. T. Powell +5 more
wiley +2 more sources
Multicentre study of prepectoral breast reconstruction using acellular dermal matrix [PDF]
A UK multicentre audit of direct‐to‐implant prepectoral breast reconstructions using acellular dermal matrix was conducted for all patients operated on from January 2015 to December 2017 across 18 centres. In a median follow‐up of 9·7 months, the major complication rate was 15·3 per cent and the 90‐day implant removal rate 4·9 per cent.
M. Chandarana +24 more
wiley +2 more sources
Multicentre study of perioperative versus adjuvant chemotherapy for resectable colorectal liver metastases [PDF]
This study aimed to estimate the effect of neoadjuvant FOLFOX in patients undergoing upfront resectable colorectal liver metastases. After adjustment, no significant impact of FOLFOX was detected, suggesting that upfront surgery may be acceptable in patients with limited disease.
M.‐A. Allard +16 more
wiley +2 more sources
Prediction of a positive circumferential resection margin at surgery following neoadjuvant chemotherapy for adenocarcinoma of the oesophagus [PDF]
A positive circumferential resection margin (CRM) has been shown to be an adverse prognostic indicator after oesophagectomy for adenocarcinoma. Clinical tumour status, tumour volume, poor differentiation, lack of response following chemotherapy and radiological assessment of invasion can be used to predict CRM positivity in oesophageal adenocarcinoma ...
W. R. C. Knight +30 more
wiley +2 more sources
Consenso de expertos basado en la evidencia: perfilamiento y manejo del carcinoma epitelial de ovario de alto grado avanzado [PDF]
Introducción y objetivo: el abordaje de pacientes con cáncer epitelial de ovario (CEO) de alto grado avanzado o metastásico ha ido evolucionando a través del tiempo con el advenimiento de nuevas terapias y estrategias multimodales.
Marc E Pierre +11 more
doaj +2 more sources
Objective: The aim of this study is to determine the hospital’s efficiency as regards neoadjuvant chemotherapy for the resection of initially unresectable metastases for patients with metastatic primary colorectal cancer and to describe the chemotherapy used. Methods: Descriptive, retrospective study of patients with colorectal cancer from 2004 to 2007.
S. Redondo Capafons +3 more
exaly +2 more sources
Prognostic impact of Ki‐67 proliferative index in resectable pancreatic ductal adenocarcinoma [PDF]
The aim of this retrospective cohort study was to analyse the role of Ki‐67 as a prognostic factor in a cohort of patients with resected pancreatic ductal adenocarcinoma. Ki‐67 index was identified as an independent predictor of poor disease‐specific and disease‐free survival.
I. Pergolini +9 more
wiley +2 more sources

