Results 91 to 100 of about 11,113 (225)
Dimeric quinacrines as chemical tools to identify PPT1, a new regulator of autophagy in cancer cells
Molecular & Cellular Oncology, 2018 DQ661 is a novel dimeric quinacrine that affects multiple lysosomal functions (autophagy and macropinocytosis) and mTORC1 (mechanistic target of rapamycin) activity by specifically targeting protein-palmitoyl thioesterase 1 (PPT1).
Michael C. Nicastri +3 more
doaj +1 more source
Determination of sex from tooth pulp tissue
Libyan Journal of Medicine, 2010 Objective: This study was carried out to determine the reliability of sex determination from teeth pulp tissue. Patients and methods: This study was carried on 60 maxillary and mandibular premolars and permanent molars (30 male teeth and 30 female teeth)
Gajendra Veeraraghavan +5 more
doaj +1 more source
Biological Research, 2002 In this study, we showed the effect of the betamethasone, sulindac and quinacrine alone or combined, on the inflammatory angiogenesis promoted by polyurethane sponge on mice.
JULIO ILLANES +6 more
doaj
Journal of Experimental & Clinical Cancer Research, 2019 Background Glioblastoma multiforme (GBM), due to its location, aggressiveness, heterogeneity and infiltrative growth, is characterized by an exceptionally dismal clinical outcome.
Silvia Matteoni +14 more
doaj +1 more source
Frontiers in Pharmacology, 2017 Adenosine triphosphate (ATP) is an important extracellular neurotransmitter that participates in several critical processes like cell differentiation, neuroprotection or axon guidance.
Aida Menéndez-Méndez +17 more
doaj +1 more source
What's the most effective treatment for giardiasis? [PDF]
, 2008 A single 2-g dose of tinidazole is the best treatment (strength of recommendation [SOR]: A, based on meta-analysis). Other drugs, such as nitazoxanide, metronidazole, mebendazole, and albendazole, can also be used (SOR: A, based on randomized controlled ...
Kiser, Jeffrey D. +1 more
core
A survey of chromosome anomalies in Malta [PDF]
, 1989 433 individuals referred for chromosome analysis between 1983 and 1987 were included in the survey. Among individuals with dysmorphic features or congenital anomalies 42% of babies referred in the neonatal period and 12 to 30% of individuals in older age
Cuschieri, Alfred, Gauci, Sandra
core
Heterogeneity of endothelial dysfunction in hypertension [PDF]
, 2017 The endothelium may play a role as a target and mediator of hypertension. Due to its anatomical position, it is very exposed to mechanical forces; as a source of vasoactive material it may participate in increasing peripheral vascular resistance and in ...
Lüscher, T. F.
core
Altered urothelial ATP signaling in a major subset of human overactive bladder patients with pyuria [PDF]
, 2016 Overactive Bladder (OAB) is an idiopathic condition, characterized by urgency, urinary frequency, and urgency incontinence, in the absence of routinely traceable urinary infection.
Balachandran, AA +14 more
core
A comprehensive revision on the use of quinoline antimalarial drugs as leishmanicidal agents
Frontiers in ChemistryAntimalarial drugs based on quinolines have been widely used as leishmanicidal agents for either cutaneous or visceral leishmaniasis models. Herein, we showed the leishmanicidal response against in vitro models of different Leishmania spp. and against in
Romina E. Avanzo +3 more
doaj +1 more source