Results 81 to 90 of about 11,113 (225)
Alzheimer's &Dementia, Volume 21, Issue S5, December 2025.Abstract Background Magnetic resonance spectroscopy (MRS) offers a non‐invasive modality to explore metabolic changes associated with Alzheimer’s disease (AD) pathogenesis and treatment efficacy. Studies in both humans and animal models have observed elevated choline in AD which may suggest an increase in cell membrane breakdown by phospholipase A2 ...
Emily Hiles +6 more
wiley +1 more source
Acta Societatis Botanicorum Poloniae, 2014 The effect of inhibitors of plasma membrane oxidoreductases (quinacrine and dicumarol) and H+-ATPase (dicyclohexylcarbodiimide and orthovanadate) on ammonium uptake by Pisum arvense seedlings and the activities of H+-ATPase and NADH-ferricyanide ...
Genowefa Kubik-Dobosz +4 more
doaj +1 more source
The Role and Therapeutic Potential of the cGAS‐STING Signaling Pathway in Alzheimer's Disease
Brain and Behavior, Volume 15, Issue 12, December 2025.This work reveals the relationship between the cGAS‐STING signaling pathway and the pathological mechanisms of Alzheimer's disease.The role of the cGAS‐STING signaling pathway in AD pathology. AD leads to the production of neutrophil extracellular traps (NETs), endoplasmic reticulum (ER) stress, and the release of mitochondrial DNA (mtDNA) and nuclear ...
Xue Li, Wei Gao, Qiuyan Ye, Honglin Li
wiley +1 more source
The multifocal pattern electroretinogram in chloroquine retinopathy [PDF]
, 2004 Purpose: Optimal screening for ocular toxicity caused by chloroquine and hydroxychloroquine is still controversial. With the multifocal pattern electroretinogram (mfPERG), a new electrophysiological technique has recently become available to detect early
Arden, G. B. +4 more
core +1 more source
Zhongguo aizheng zazhi, 2019 Background and purpose: With the clinical application of sequential L-asparaginase-containing chemotherapy and radiotherapy as well as immune checkpoint inhibitors, both rates of response and progression-free survival of patients with extranodal natural ...
YANG Xue +6 more
doaj
Ovine recombinant PrP as an inhibitor of ruminant prion propagation in vitro [PDF]
, 2017 Prion diseases are fatal and incurable neurodegenerative diseases of humans and animals. Despite years of research, no therapeutic agents have been developed that can effectively manage or reverse disease progression. Recently it has been identified that
Gough, Kevin C. +2 more
core +1 more source
Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1965 La coccidiose intestinale du mouton est signalée au Sénégal pour la 1re fois, à Sébikotane, près de Thiès. Cinq espèces sont en cause: E. ninakohlyakimovae, E. ahsata, E. arloingi, E. parva et E. faurei. De simples mesures d'hygiène et un traitement à la
Georges Vassiliades
doaj +1 more source
Cell wall perturbation sensitizes fungi to the antimalarial drug chloroquine. [PDF]
, 2013 Journal ArticleResearch Support, Non-U.S. Gov'tCopyright © 2015 by the American Society for Microbiology.Post print version deposited in accordance with SHERPA RoMEO guidelines.Chloroquine (CQ) has been a mainstay of antimalarial drug treatment for ...
Avery, SV +5 more
core +5 more sources
Clofazimine Induced Suicidal Death of Human Erythrocytes
Cellular Physiology and Biochemistry, 2015 Background/Aims: The antimycobacterial riminophenazine clofazimine has previously been shown to up-regulate cellular phospholipase A2 and to induce apoptosis.
Arbace Officioso +3 more
doaj +1 more source
The Evaluation of Mefloquine Drug Repurposing on Acute Myeloid Leukemia [PDF]
, 2018 The aim of this study is to observe cell proliferation, cell viability, apoptosis, and autophagy on acute myeloid leukemia (AML) cell lines, NB4 and U937, with the drug repurposing of mefloquine (MQ).
Corey, Seth +3 more
core +1 more source