Results 61 to 70 of about 11,113 (225)
Glioma, 2018 Background: The alkylating agent temozolomide (TMZ) is widely used in glioblastoma multiforme (GBM) therapy. Unfortunately, TMZ-resistance frequently occurs in recurrent GBM and is the major cause of treatment failure.
Pingde Zhang +6 more
doaj +1 more source
Food Frontiers, Volume 7, Issue 3, May 2026.Garcinone C (Gar. C), a xanthone derived from mangosteen (Garcinia mangostana), suppresses triple‐negative breast cancer growth and stemness by inducing mitochondrial‐mediated apoptosis and inhibiting the Wnt/β‐catenin pathway, highlighting its potential as a natural compound for the prevention and treatment TNBC.
Danhong Zheng +4 more
wiley +1 more source
Dose-dependent ATP depletion and cancer cell death following calcium electroporation, relative effect of calcium concentration and electric field strength. [PDF]
PLoS ONE, 2015 Electroporation, a method for increasing the permeability of membranes to ions and small molecules, is used in the clinic with chemotherapeutic drugs for cancer treatment (electrochemotherapy).
Emilie Louise Hansen +5 more
doaj +1 more source
Tripartite phase separation of two signal effectors with vesicles priming B cell responsiveness. [PDF]
, 2020 Antibody-mediated immune responses rely on antigen recognition by the B cell antigen receptor (BCR) and the proper engagement of its intracellular signal effector proteins.
Becker, S. +10 more
core +2 more sources
Chromaffin Versus Platelet Granules: What We Have Learned From Chromaffin Cells for Human Studies
Journal of Neurochemistry, Volume 170, Issue 5, May 2026.Chromaffin cells and platelets both utilize exocytosis to release biogenic amines stored within large dense‐core vesicles—specifically chromaffin granules (epinephrine) and δ‐granules (serotonin). While the chromaffin cell is the foundational model for studying the secretory pathway, platelets offer a highly accessible human cell source for clinical ...
Ricardo Borges
wiley +1 more source
Journal of Research in Medical Sciences, 2002 Introduction. Cimetidine and quinacrine have protective effect on gastroduodenal lesions. In this study we compared efficacy of cimetidine and quinacrine for prevention of stress and aspirin Induced Peptic Ulcer. Methods.
L BORJIAN, A.R RAHMANI
doaj
The effect of Quinacrine on MMP1 Gene Expression in MDA-MB 231 and MCF7 cell lines of breast cancer
Fiyz̤, 2020 Background: Breast cancer is the most frequent malignancy in women worldwide and occurs when cells in the breast begin to grow out of control. Matrix metalloproteinases (MMP), including MMP1 protein, are important in the progression of various types of ...
Ganjkhanlou Z +3 more
doaj
薬剤誘発性リン脂質症のバイオマーカーとしての血漿中馬尿酸とフェニルアセチルグリシンに関する研究 [PDF]
, 2018 筑波大学 (University of Tsukuba ...
Kamiguchi hidenori, 上口 英則
core +1 more source
Constant Transmission Properties of Variant Creutzfeldt-Jakob Disease in 5 Countries [PDF]
, 2012 Variant Creutzfeldt-Jakob disease (vCJD) has been reported in 12 countries. We hypothesized that a common strain of agent is responsible for all vCJD cases, regardless of geographic origin.
Abigail B. Diack +26 more
core +5 more sources
Hydroxychloroquine Patch Test Positivity in a Patient With Systemic Lupus Erythematosus
Contact Dermatitis, EarlyView.
Alexa G. Ries +3 more
wiley +1 more source