Molecular and Microbial Microenvironments in Chronically Diseased Lungs Associated with Cystic Fibrosis. [PDF]
, 2019 To visualize the personalized distributions of pathogens and chemical environments, including microbial metabolites, pharmaceuticals, and their metabolic products, within and between human lungs afflicted with cystic fibrosis (CF), we generated three ...
Ackermann, Gail +26 more
core +1 more source
Intestinal colonization due to Escherichia coli ST131: Risk factors and prevalence [PDF]
, 2018 Background Escherichia coli sequence type 131 (ST131) is a successful clonal group that has dramatically spread during the last decades and is considered an important driver for the rapid increase of quinolone resistance in E. coli.
A Talaminos +10 more
core +1 more source
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT Objective To estimate miscarriage risk following gestational antimicrobial exposure while addressing biases that have affected previous studies. Design Population‐based cohort study. Setting Linkage of four nationwide registries: Medical Birth Registry of Norway (MBRN), Norwegian Prescribed Drug Registry (NorPD), Norwegian Patient Registry ...
Thomas Boissiere‐O'Neill +3 more
wiley +1 more source
1,2-Dimethyl-4-quinolone and xanthevodine, minor alkaloids from the leaves of Acronychia baueri Schott [PDF]
, 1966 JA Lamberton
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Ciprofloxacin reduces the stimulation of prostaglandin E2 output by interleukin-1 in human tendon-derived cells [PDF]
, 2003 Fluoroquinolone antibiotics such as ciprofloxacin can induce tendon pathology and have various effects on tendon-derived cells in culture. We are investigating whether ciprofloxacin modifies signalling responses in tendon cells.
Corps, AN +5 more
core +1 more source
Alkaloids of the Australian Rutaceae: Lunasia quercifolia. IV. Identification of a minor constituent as 5-Hydroxy-1-methyl-2-phenyl-4-quinolone and the preparation of an angular isomer of ( - )-Lunine [PDF]
, 1968 NK Hart +3 more
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Quinolone signaling in the cell-to-cell communication system of Pseudomonas aeruginosa.
Proceedings of the National Academy of Sciences of the United States of America, 1999 Numerous species of bacteria use an elegant regulatory mechanism known as quorum sensing to control the expression of specific genes in a cell-density dependent manner.
E. Pesci +6 more
semanticscholar +1 more source
Andrology, EarlyView.Abstract Background G protein‐coupled receptors are a large and functionally diverse family of membrane receptors involved in a number of biological processes. Like other proteins, G protein‐coupled receptors need to be properly folded in order to traffic to the plasma membrane and interact with agonist.
Alfredo Ulloa‐Aguirre +5 more
wiley +1 more source
BMC Evolutionary Biology, 2007 BackgroundDistinguishing the recent introduction of quinolone resistant gonococci into a population from diversification of resistant strains already in the population is important for planning effective infection control strategies. We applied molecular
Marcos Pérez-Losada +5 more
semanticscholar +1 more source
Protein tyrosine phosphatases as emerging targets for cancer immunotherapy
British Journal of Pharmacology, EarlyView.Abstract Contemporary strategies in cancer immunotherapy, despite remarkable success, remain constrained by inherent limitations such as suboptimal patient responses, the emergence of drug resistance, and the manifestation of pronounced adverse effects. Consequently, the need for alternative strategies for immunotherapy becomes clear.
Zihan Qu, Jiajun Dong, Zhong‐Yin Zhang
wiley +1 more source