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A biocatalytic platform for the production of substituted 2-quinolones and (thio)coumarins
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Medical Clinics of North America, 1995
Fluoroquinolones represent a major advance in antimicrobial chemotherapy. Currently, there are five fluoroquinolones approved by the FDA, and many more quinolones are expected to become available in years to come. Although their clinical utility is constantly expanding, they have been best studied in complicated urinary tract infections, chronic ...
B, Suh, B, Lorber
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Fluoroquinolones represent a major advance in antimicrobial chemotherapy. Currently, there are five fluoroquinolones approved by the FDA, and many more quinolones are expected to become available in years to come. Although their clinical utility is constantly expanding, they have been best studied in complicated urinary tract infections, chronic ...
B, Suh, B, Lorber
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Molecular mechanisms associated with quinolone resistance in Enterobacteriaceae: review and update.
Transactions of the Royal Society of Tropical Medicine and Hygiene, 2020BACKGROUND Quinolones are broad-spectrum antibiotics, which are used for the treatment of different infectious diseases associated with Enterobacteriaceae.
R. Azargun+7 more
semanticscholar +1 more source
Clinics in Dermatology, 2003
T he quinolones are an important class of broad-spectrum antimicrobials in common use today. Multiple quinolones are currently available in the United States (Table 1) with broader spectrums and longer half-lives than older quinolones, such as nalidixic acid (Fig 1A).
David Sable, George J. Murakawa
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T he quinolones are an important class of broad-spectrum antimicrobials in common use today. Multiple quinolones are currently available in the United States (Table 1) with broader spectrums and longer half-lives than older quinolones, such as nalidixic acid (Fig 1A).
David Sable, George J. Murakawa
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Drugs, 1999
Reactions of the gastrointestinal tract, the CNS and the skin are the most often observed adverse effects during therapy with fluoroquinolones. At least for some of the newer fluoroquinolones a steep dose-response relationship of adverse effects seems to exist. Pathogenesis of the neurotoxic effects of fluoroquinolones is still unknown. Among the newer
Ralf Stahlmann, Hartmut Lode
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Reactions of the gastrointestinal tract, the CNS and the skin are the most often observed adverse effects during therapy with fluoroquinolones. At least for some of the newer fluoroquinolones a steep dose-response relationship of adverse effects seems to exist. Pathogenesis of the neurotoxic effects of fluoroquinolones is still unknown. Among the newer
Ralf Stahlmann, Hartmut Lode
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Quinolones in the Elderly [PDF]
Aging results in a number of physiological changes that can affect drug disposition; these include reduced gastric acidity, decreased intestinal motility, lower lean body mass, and reduction in renal function. The age-related decline in renal function is the most important of these factors when administering quinolones to elderly patients.
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