Results 101 to 110 of about 60,375 (278)

Quinolones and their N-oxides as inhibitors of mitochondrial complexes I and III [PDF]

, 1997
4(1H)-quinolones (2-alkyl- (1), 2-alkyl-3-methyl- (2), 2-methyl-3-alkyl- (3), 1-hydroxy-2-methyl-3-alkyl- (4) and 1-hydroxy-2-alkyl- (5)) with n-alkyl side chains varying from C5 to C17 have been synthesized and tested for biological activity in ...
Draber, Wilfried, Höfle, Gerhard, Oettmeier, Walter, Reil, Ellen   +3 more
core   +1 more source

Mitochondrial dynamics in autoimmune diseases

Rheumatology &Autoimmunity, EarlyView.
Roles of mitochondrial dynamic imbalance in autoimmune diseases. The imbalance of mitochondrial fusion and fission is involved in the occurrence and development of autoimmune diseases, including systemic lupus erythematosus, Sjogren's syndrome, rheumatoid arthritis, multiple sclerosis, myasthenia gravis, type 1 diabetes, psoriasis, and autoimmune ...
Ruicong Ma, Cheng Zhang, Jiaqing Liu, Jinyi Ren, Xia Li, Ying Zhao   +5 more
wiley   +1 more source

Forging a New Frontier: Antimicrobial Peptides and Nanotechnology Converging to Conquer Gastrointestinal Pathogens

Small, EarlyView.
This review explores the potential of antimicrobial peptides (AMPs) and nanotechnology for the treatment of gastrointestinal infections. It analyzes bacterial resistance mechanisms, the antimicrobial actions of AMPs, and advances in nanocarriers, such as lipid‐based, polymeric, metallic, and mesoporous silica systems, that enhance peptide protection ...
Christian Shleider Carnero Canales, Cesar Augusto Roque‐Borda, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Uner Josseph Pinto Apaza, Vanderson de Jesus Silva, Laura Maria Duran Gleriani Primo, Maura Jennifer Martínez‐Morales, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +10 more
wiley   +1 more source

Fluorescent Antibiotics: Bridging Diagnostic and Therapy in the Fight against Bacterial Infections

Small Science, EarlyView.
This review critically evaluates fluorescent antibiotics as promising agents combining diagnostic precision with therapeutic efficacy. It highlights advances in probe design, chemical conjugation strategies, real‐time imaging applications, selective pathogen detection, and targeted therapy. The potential to combat antimicrobial resistance is discussed,
Tan Phuoc Ton, Richard Bright, Vi Khanh Truong, Krasimir Vasilev   +3 more
wiley   +1 more source

Synthesis and Physico-Chemical Characterization of the Cu(II), Pd(II) and Ru(III) Complexes with Difloxacin

Proceedings, 2019
The growing interest in metal-quinolone complexes is sustained by a large number of compounds obtained and tested for antibacterial [1], antitumoral [1,2], antifungal [1], and antiparasitic [3] properties. [...]
Ana-Mădălina Măciucă, Mihaela Badea, Rodica Olar, Alexandra Cristina Munteanu, Valentina Uivarosi   +4 more
doaj   +1 more source

Complexation of norfloxacin with DNA in the presence of caffeine [PDF]

, 2006
1H NMR spectroscopy (500 MHz) has been used to quantify the complexation of the antibacterial antibiotic Norfloxacin (NOR) with DNA in the presence of Caffeine (CAF). Separate studies have been made for the self-association of NOR, its hetero-association
Davies, David B., Evstigneev, M.P., Rybakova, K.A.   +2 more
core   +1 more source

Analysis and Study of Covalent Organic Frameworks in Electrochemical Sensors for Water Environment Pollutant Detection

Small Structures, EarlyView.
This summary highlights covalent organic framework (COF)‐based electrochemical sensors for detecting water pollutants like antibiotics, heavy metals, pesticides, bisphenols, and toxins. It covers diverse COF synthesis methods, including solvothermal, ionothermal, and microwave‐assisted techniques.
Bo Long, Qi Liu, Qian Zhang, Qiongqiong Xing, Liying Deng, Fangfang Qu, Liwei Wang, Dapeng Ye, Zhanhui Yuan   +8 more
wiley   +1 more source

Spread of Antibiotic Resistance in Aquatic Environments: E. coli as a Case Study

Proceedings, 2018
The aim of this study was to gather information on the spread of antibiotic resistance in Escherichia coli isolates from wells, boreholes and untreated drinking water in islands of Greece. We analyzed for antibiotic resistance 235 E.
Maria Adamantia Efstratiou, Marina Bountouni, Efthimios Kefalas   +2 more
doaj   +1 more source

Exposure to Systemic Antimicrobials During Pregnancy and Risk of Miscarriage: A Population‐Based Registry Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To estimate miscarriage risk following gestational antimicrobial exposure while addressing biases that have affected previous studies. Design Population‐based cohort study. Setting Linkage of four nationwide registries: Medical Birth Registry of Norway (MBRN), Norwegian Prescribed Drug Registry (NorPD), Norwegian Patient Registry ...
Thomas Boissiere‐O'Neill, Marleen M. H. J. van Gelder, Hilde M. Engjom, Hedvig M. E. Nordeng   +3 more
wiley   +1 more source

Drug-resistant Escherichia coli, Rural Idaho

Emerging Infectious Diseases, 2005
Stool carriage of drug-resistant Escherichia coli in home-living residents of a rural community was examined. Carriage of nalidixic acid–resistant E. coli was associated with recent use of antimicrobial agents in the household.
Elizabeth L. Hannah, Frederick J. Angulo, James R. Johnson, Bassam Haddadin, Jacquelyn Williamson, Matthew H. Samore   +5 more
doaj   +1 more source