Results 91 to 100 of about 64,524 (236)
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT Objective To estimate miscarriage risk following gestational antimicrobial exposure while addressing biases that have affected previous studies. Design Population‐based cohort study. Setting Linkage of four nationwide registries: Medical Birth Registry of Norway (MBRN), Norwegian Prescribed Drug Registry (NorPD), Norwegian Patient Registry ...
Thomas Boissiere‐O'Neill +3 more
wiley +1 more source
Addiction, EarlyView.Abstract Background and aims Tobacco‐cannabis co‐use is associated with increased psychosocial and health harms; however, the treatment literature assessing the impact of co‐use has been mixed and suffers from critical limitations. To date, no prospective studies have evaluated the degree to which cannabis co‐use affects tobacco cessation, nor are ...
Erin A. McClure +6 more
wiley +1 more source
From Erythromycin to Azithromycin and New Potential Ribosome-Binding Antimicrobials
Antibiotics, 2016 Macrolides, as a class of natural or semisynthetic products, express their antibacterial activity primarily by reversible binding to the bacterial 50S ribosomal subunits and by blocking nascent proteins’ progression through their exit tunnel in bacterial
Dubravko Jelić, Roberto Antolović
doaj +1 more source
The effect of combined sewer overflows on the abundance of antibiotic resistance genes and bacteria in the James River [PDF]
, 2017 Antibiotic resistance is a major threat to human health. Clinical situations are the main focus for antibiotic resistance research, but understanding the spread of resistance in the environment is also vital.
Levengood, Enjolie
core +1 more source
Acta Ophthalmologica, EarlyView.Abstract Purpose To report treatment patterns, time‐to‐resolution (TTR) and aetiologies of bacterial keratitis (BK) infections treated in a specialized hospital‐based cornea clinic in Sweden. Methods Retrospective study based on electronic health records screened during the period 2010–2019. The study included only culture‐confirmed cases of BK.
Jenny Roth +5 more
wiley +1 more source
Molecules, 2019 Infection from multidrug resistant bacteria has become a growing health concern worldwide, increasing the need for developing new antibacterial agents. Among the strategies that have been studied, biofilm inhibitors have acquired relevance as a potential
Mariana Paola Espinosa-Valdés +8 more
doaj +1 more source
Estimating the Effects of Global Patent Protection in Pharmaceuticals: A Case Study of Quinolones in India [PDF]
Under the TRIPS agreement, WTO members are required to enforce product patents for pharmaceuticals. The debate about the merits of this requirement has been extremely contentious. Many low income economies claim that patent protection for pharmaceuticals
Panle Jia +2 more
core
Antibiotic Exposure in Early Life and Risk of Type 1 Diabetes: A Meta‐Analysis
Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Background Early‐life antibiotic use may increase the risk of childhood type 1 diabetes (T1D), potentially through gut microbiota dysbiosis and associated effects on immune development. This meta‐analysis evaluated associations between early‐life antibiotic use and T1D.
Sharan Ram +5 more
wiley +1 more source
The FEBS Journal, EarlyView.Quinolones are valuable scaffolds for drug discovery but are rare in nature. Here, we show that two fungal enzymes, AthePKS and FerePKS, can generate 2‐quinolones and two additional heteroaromatic scaffolds. Using AthePKS, we designed an artificial enzymatic cascade towards an antimicrobial quinolone from a simple precursor and implemented it in E ...
Nika Sokolova +5 more
wiley +1 more source
Veterinary Medicine and Science, 2020 Monitoring and surveillance of antimicrobial usage in animals is a public health concern and different methods are currently discussed widely in public, science and politics.
Roswitha Merle, Borris Meyer‐Kühling
doaj +1 more source