Results 1 to 10 of about 72,300 (203)

Assessment of Knowledge Regarding Safety Profile, Use, and Boxed Warnings of Fluoroquinolones Among Healthcare Professionals in Saudi Arabia: A Potential Implication for Drug Regulatory Authorities

Frontiers in Medicine, 2022
BackgroundDespite a series of “boxed warnings” (BWs) issued by the US Food and Drug Administration (FDA), fluoroquinolones (FQs) are among the most prescribed antibiotics across the world.
Tauqeer Hussain Mallhi, Abdullah Salah Alanazi, Abdullah Salah Alanazi, Yusra Habib Khan, Nasser Hadal Alotaibi, Muhammad Salman, Abdulaziz Ibrahim Alzarea, Salah-Ud-Din Khan, Nabil K. Alruwaili, Alaa Salah Alenazi, Ahmed D. Alatawi, Zafar Iqbal, Muhammad Hammad Butt, Muhammad Shahid Iqbal   +13 more
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Fluoroquinolonas Fluoroquinolones

Iatreia, 1990
<p class="MsoNormal"><span style="font-size: 10pt; font-family: Arial">En este artículo se resumen aspectos históricos, químicos y farmacocinéticos de las fluoroquinolonas así como su mecanismo de acción, su espectro antibacteriano, las ...
Jesualdo Fuentes
doaj  

Analyses of Adverse Drug Reactions to Fluoroquinolones in Spontaneous Reports Before and After the Referral and in Clinical Routine Cases

Drugs in R&D
Introduction In November 2018, the European Medicines Agency (EMA) restricted the use of fluoroquinolones (used by mouth, injections or inhalation) in the context of a referral due to long-lasting and potentially irreversible adverse drug reactions (ADRs)
Diana Dubrall, Julia Wicherski, Maike Below, Jan Görtzen-Patin, Matthias Schmid, Sven Zenker, Britta Haenisch, Bernhardt Sachs   +7 more
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Fluoroquinolone Antimicrobial Agents [PDF]

New England Journal of Medicine, 1989
The fluoroquinolones, a new class of potent orally absorbed antimicrobial agents, are reviewed, considering structure, mechanisms of action and resistance, spectrum, variables affecting activity in vitro, pharmacokinetic properties, clinical efficacy, emergence of resistance, and tolerability. The primary bacterial target is the enzyme deoxyribonucleic
D C, Hooper, J S, Wolfson
openaire   +3 more sources

The use of fluoroquinolones in the treatment of community-acquired pneumonia and their cardiotoxic effects [PDF]

Клиническая микробиология и антимикробная химиотерапия
Fluoroquinolones (FQ) are widely used in the treatment of community-acquired pneumonia (CAP) in certain cases specified in Russian clinical guidelines. However, FQ are known to have cardiotoxic effects. There have been reports on proarrhythmogenic effect
Gamayunov D.Yu., Kalyagin A.N., Orlova G.M., Balabina N.M., Sinkova G.M., Sinkov A.V.   +5 more
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The future of fluoroquinolones

Annals of Medicine, 2000
The mutant prevention concentration (MPC) is a new measure of antibiotic potency above which a microbe must attain two concurrent resistance mutations for growth. For some C-8-methoxy fluoroquinolone-pathogen combinations, the value of MPC is below human serum drug concentration achieved with standard doses.
openaire   +2 more sources

Rapid evolution of fluoroquinolone-resistant Escherichia coli in Nigeria is temporally associated with fluoroquinolone use

BMC Infectious Diseases, 2011
Background Antibiotic resistance has necessitated fluoroquinolone use but little is known about the selective forces and resistance trajectory in malaria-endemic settings, where selection from the antimalarial chloroquine for fluoroquinolone-resistant ...
Lamikanra Adebayo, Crowe Jennifer L, Lijek Rebeccah S, Odetoyin Babatunde W, Wain John, Aboderin A Oladipo, Okeke Iruka N   +6 more
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Efficiency of danofloxacin in treatment of pig colibacteriosis

Біологія тварин, 2020
The article presents the study results of the third-generation fluoroquinolone antibiotic danofloxacin efficacy and safeness in the treatment of pig colibacillosis.
T. I. Stetsko
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To compare the in vitro activity of 3 popular fluoroquinolones against common respiratory and middle ear pathogens

Bengal Journal of Otolaryngology and Head Neck Surgery, 2013
Antibiotic resistance among respiratory tract pathogens is increasing worldwide. Beta-lactam-resistant as well as macrolide and fluoroquinolone-resistant strains of the commonest pathogens  are being isolated with increasing frequency in manycountries .
Soma Sarkar, Manideepa Sengupta, Puranjay Saha, Soumyabrata Nag   +3 more
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Determination of 20 fluoroquinolones in milk based on magnetic molecularly imprinted microsphere and aggregation induced emission luminongen

Food Chemistry: X
The residues of fluoroquinolones in foods of animal origin posed many threats to the consumer's health. The aim of this study was to developed a magnetic molecularly imprinted microsphere and aggregation induced emission luminogen based semi-homogeneous ...
Su Han Wang, Jian Ping Wang, Cheng Feng
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