Results 21 to 30 of about 72,300 (203)
Transporter and metabolizer gene polymorphisms affect fluoroquinolone pharmacokinetic parameters
Tuberculosis (TB) is an infectious disease that occurs globally. Treatment of TB has been hindered by problems with multidrug-resistant strains (MDR-TB). Fluoroquinolones are one of the main drugs used for the treatment of MDR-TB.
Nurul Annisa +5 more
doaj +1 more source
Pharmacodynamics of Fluoroquinolones [PDF]
Fluoroquinolone antimicrobial agents are highly active against aerobic or facultative gram-negative bacilli. The fluoroquinolones have been shown to be very concentration dependent in their rates of killing and also have a postantibiotic effect against most gram-negative pathogens.
H, Lode, K, Borner, P, Koeppe
openaire +2 more sources
Background To evaluate the safety of using fluoroquinolones in pediatric population in Taiwan. Methods Patients aged 0~18 years old with fluoroquinolones prescriptions ≥5 consecutive days during year 2000 to 2013 were selected from the National Health ...
Pei-Han Yu +6 more
doaj +1 more source
Fluoroquinolones (FQs) are one of the most commonly prescribed classes of antibiotics. Although they were initially well tolerated in randomized clinical trials, subsequent epidemiological studies have reported an increased risk of threatening, severe, long-lasting, disabling and irreversible adverse effects (AEs), related to neurotoxicity and collagen
José Barberán +6 more
openaire +2 more sources
Systemic use of fluoroquinolone in children [PDF]
Fluoroquinolones are an important class of antibiotics that are widely used in adult patients because of their broad spectrum of activity, good tissue penetration, and oral bioavailability.
Soo-Han Choi +2 more
doaj +1 more source
A comparison of fluoroquinolones versus other antibiotics for treating enteric fever: meta-analysis. [PDF]
OBJECTIVES: To review evidence supporting use of fluoroquinolones as first line agents over other antibiotics for treating typhoid and paratyphoid fever (enteric fever). DESIGN: Meta-analysis of randomised controlled trials.
Thaver, D +11 more
core +1 more source
Streptococcus pneumoniae (S. pneumoniae) is a bacterial species often associated with the occurrence of community-acquired pneumonia (CAP). CAP refers to a specific kind of pneumonia that occurs in individuals who acquire the infection outside of a ...
Nurul Izzaty Najwa Zahari +14 more
doaj +1 more source
Background: Extremely low concentrations of ciprofloxacin may select for antimicrobial resistance. A recent global survey found that ciprofloxacin concentrations exceeded safe levels at 64 sites. In this study, I assessed if national median ciprofloxacin
Chris Kenyon
doaj +1 more source
Comparative Studies of Fluoroquinolones in the Treatment of Urinary Tract Infections [PDF]
The results of comparative trials of fluoroquinolones for the treatment of uncomplicated and complicated urinary tract infections (UTI) were reviewed. Severalrandomized, comparative trials showedthat in uncomplicatedUTI norfloxacin, ciprofloxacin, and ...
Glauser, M. P. +4 more
core +2 more sources
Biotransformation of the Fluoroquinolone, Levofloxacin, by the White-Rot Fungus Coriolopsis gallica
The wastewater from hospitals, pharmaceutical industries and more generally human and animal dejections leads to environmental releases of antibiotics that cause severe problems for all living organisms.
Amal Ben Ayed +17 more
doaj +1 more source

