Results 41 to 50 of about 56,658 (237)

Analyses of Adverse Drug Reactions to Fluoroquinolones in Spontaneous Reports Before and After the Referral and in Clinical Routine Cases

Drugs in R&D
Introduction In November 2018, the European Medicines Agency (EMA) restricted the use of fluoroquinolones (used by mouth, injections or inhalation) in the context of a referral due to long-lasting and potentially irreversible adverse drug reactions (ADRs)
Diana Dubrall, Julia Wicherski, Maike Below, Jan Görtzen-Patin, Matthias Schmid, Sven Zenker, Britta Haenisch, Bernhardt Sachs   +7 more
doaj   +1 more source

Fecal Microbiota Transplantation and Microbiota‐Based Therapeutics in Allogeneic Hematopoietic Stem Cell Transplantation: Current Evidence and Future Directions

Clinical Pharmacology &Therapeutics, EarlyView.
The intestinal microbiome is a key regulator of immune homeostasis, metabolism, and epithelial barrier integrity. In patients with malignant hematological diseases, particularly those undergoing hematopoietic stem cell transplantation, microbiome perturbations by reduced diversity, pathobiont expansion, and loss of beneficial metabolites are common as ...
Bálint Gergely Szabó, Dorina Korózs, Michal Bator, Krisztina Jeszenszky, Viktor Lakatos, László Gopcsa, Péter Reményi, János Sinkó   +7 more
wiley   +1 more source

Carbon‐Negative Upcycling of Sewage Sludge into Superiorly Stable Gel Via Liquid‐Phase Utilization Strategy for Water‐Remediation

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
This work developed a low‐temperature sludge hydrothermal coupled with gel crosslinking strategy which could upgrade the waste liquid generated from sewage sludge hydrothermal treatment into the hydrothermal‐liquid‐gel. The inventive hydrothermal‐liquid‐gel exhibited the enhanced pollutant removal capability, high synthetic stability, and superior ...
Zifan Liu, Sunxinyi Wang, Lingxiao Lu, Weiguo Zhang, Qiang Zheng, Cailiang Yue, Huimin Chang, Xiaohui Lu, Ming Xu, Zhi Qian, Qing Zhou, Fuqiang Liu, Baoshan Xing   +12 more
wiley   +1 more source

Enhanced Photocatalytic Antibiotic Micropollutants Removal Resulting From a Synergism Between Cu Single Atoms and Carbon Vacancies on Graphitic Carbon Nitride

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Scheme of the synergistic degradation for antibiotic micropollutants in the Cu/ag‐C3N4 system. Photocatalytic processes driven by visible‐light irradiation offer a sustainable means of micropollutants removal from aquatic environments without the addition of reagents.
Xiaozhe Song, Cong Yan, Qinghua Yan, Congzhe Ren, Xin Liu, Ruiyan Zhang, Lei Chen, Chongqing Xu, Zhouyang Long, Wenyu Wang, Mingming Song, Xiaoguo Shi, Hui Wang   +12 more
wiley   +1 more source

The use of fluoroquinolones in the treatment of community-acquired pneumonia and their cardiotoxic effects [PDF]

Клиническая микробиология и антимикробная химиотерапия
Fluoroquinolones (FQ) are widely used in the treatment of community-acquired pneumonia (CAP) in certain cases specified in Russian clinical guidelines. However, FQ are known to have cardiotoxic effects. There have been reports on proarrhythmogenic effect
Gamayunov D.Yu., Kalyagin A.N., Orlova G.M., Balabina N.M., Sinkova G.M., Sinkov A.V.   +5 more
doaj   +1 more source

Fluoroquinolone Antimicrobial Agents [PDF]

New England Journal of Medicine, 1989
The fluoroquinolones, a new class of potent orally absorbed antimicrobial agents, are reviewed, considering structure, mechanisms of action and resistance, spectrum, variables affecting activity in vitro, pharmacokinetic properties, clinical efficacy, emergence of resistance, and tolerability. The primary bacterial target is the enzyme deoxyribonucleic
D C, Hooper, J S, Wolfson
openaire   +3 more sources

Tracheal wash culture is not associated with bronchial infection, remodelling or inflammation in horses with asthma

Equine Veterinary Journal, EarlyView.
Abstract Background Antimicrobials are commonly prescribed for the treatment of equine asthma, despite limited evidence supporting their use. Tracheal wash (TW) bacterial culture results are known to influence antimicrobial prescription decisions. Objectives To determine whether a positive TW bacterial culture in horses with asthma is associated with ...
Laurence Leduc, Guillaume St‐Jean, Jean‐Pierre Lavoie   +2 more
wiley   +1 more source

Genomic Insights Into Spatiotemporal Dynamics of Acquired Azithromycin Resistance Genes in Salmonella Strains Worldwide

Food Safety and Health, EarlyView.
ABSTRACT Azithromycin has been used for clinical invasive infections caused by fluoroquinolone‐ and third‐generation cephalosporin‐resistant Salmonella, and mass drug administration with azithromycin has been used to reduce under‐5 mortality in children in some countries.
Yuhang Pei, Mengqi Qu, Ziru Yang, Xuebin Xu, Yanan Wang   +4 more
wiley   +1 more source

Rapid evolution of fluoroquinolone-resistant Escherichia coli in Nigeria is temporally associated with fluoroquinolone use

BMC Infectious Diseases, 2011
Background Antibiotic resistance has necessitated fluoroquinolone use but little is known about the selective forces and resistance trajectory in malaria-endemic settings, where selection from the antimalarial chloroquine for fluoroquinolone-resistant ...
Lamikanra Adebayo, Crowe Jennifer L, Lijek Rebeccah S, Odetoyin Babatunde W, Wain John, Aboderin A Oladipo, Okeke Iruka N   +6 more
doaj   +1 more source

Efficiency of danofloxacin in treatment of pig colibacteriosis

Біологія тварин, 2020
The article presents the study results of the third-generation fluoroquinolone antibiotic danofloxacin efficacy and safeness in the treatment of pig colibacillosis.
T. I. Stetsko
doaj   +1 more source