Results 11 to 20 of about 66,971 (207)

Fluoroquinolones and Biofilm: A Narrative Review [PDF]

Pharmaceuticals
Background: Biofilm-associated infections frequently span multiple body sites and represent a significant clinical challenge, often requiring a multidisciplinary approach involving surgery and antimicrobial therapy.
Luzzati, Roberto, Toc, Dan-Alexandru, Di Bella, Stefano, Stroffolini, Giacomo, Stefano Di Bella, Luigi Principe, Saverio Giuseppe Parisi, Federico Giovagnorio, Andrea De Vito, Parisi, Saverio Giuseppe, Giacomo Stroffolini, De Vito, Andrea, Dan-Alexandru Toc, Roberto Luzzati, Colpani, Agnese, Botan, Alexandru, Madeddu, Giordano, Nicholas Geremia, Alexandru Botan, Zerbato, Verena, Geremia, Nicholas, Agnese Colpani, Giovagnorio, Federico, Giordano Madeddu, Verena Zerbato, Principe, Luigi   +25 more
core   +3 more sources

Repositioning of Fluoroquinolones: A New Approach in Antitumor Therapy. [PDF]

Biology (Basel)
Fluoroquinolones are known for their antibacterial properties, but recent research has revealed their potential to inhibit the growth and proliferation of cancer cells.
da Silva JR, de Souza JB, de Oliveira LL, de Almeida Campos LA, Cavalcanti IMF.   +4 more
europepmc   +2 more sources

Fluoroquinolone Mannich bases as promising biologically beneficial molecules [PDF]

Minia Journal of Medical Research, 2021
Mannich bases, a structurally heterogeneous aminomethyl functionality, found numerous applicationsin medicinal chemistry field. Fluoroquinolones-Mannich bases here is discussed, with prominence onthe correlation between structure and biological activity ...
Mohamed Abdel-Aziz, Gamal El-Din Abuo-Rahma, Alaa Hayallah, Islam Abdel-Rahman   +3 more
doaj   +1 more source

Prevalence, risk factors and treatment outcomes of fluoroquinolones-associated tendinopathy in tuberculosis patients at university hospital, Thailand

Heliyon, 2023
Background: Tuberculosis (TB) is an epidemic disease in Thailand. Fluoroquinolones are used to treat TB and have a lengthy treatment course. Therefore, many patients may have adverse effects from these medications.
Jirarat Chongboonwatana, Varalee Terbsiri, Gompol Suwanpimolkul   +2 more
doaj   +1 more source

Recent Strategies in Design of Antitumor and Antibacterial Fluoroquinolones [PDF]

Journal of Advanced Biomedical and Pharmaceutical Sciences, 2021
Fluoroquinolones are known widely used synthetic antibacterial agents. Generally, there were some obstacles associated with their therapeutic use.
Mohamed Samir, Mohammed Ramadan, Mostafa Hamed, Mohamed Osman, Gamal Abou=Rahma   +4 more
doaj   +1 more source

Association Between Aortic Aneurysm and Aortic Dissection With Fluoroquinolones Use in Patients With Urinary Tract Infections: A Population‐Based Cohort Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Fluoroquinolones are first‐line antibiotics recommended for the treatment of complicated urinary tract infections (UTIs), with frequent reports of adverse effects of aortic aneurysm (AA) and aortic dissection (AD).
Yin‐Yang Chen, Shun‐Fa Yang, Han‐Wei Yeh, Ying‐Tung Yeh, Jing‐Yang Huang, Shao‐Lun Tsao, Chao‐Bin Yeh   +6 more
doaj   +1 more source

Fluoroquinolones’ Biological Activities against Laboratory Microbes and Cancer Cell Lines

Molecules, 2022
Development of novel derivatives to rein in and fight bacteria have never been more demanding, as microbial resistance strains are alarmingly increasing.
Ghadeer A. R. Y. Suaifan, Aya A. M. Mohammed, Bayan A. Alkhawaja   +2 more
doaj   +1 more source

The Resistance Mechanism of Mycoplasma bovis From Yaks in Tibet to Fluoroquinolones and Aminoglycosides

Frontiers in Veterinary Science, 2022
Mycoplasma bovis (M. bovis) is one of the important pathogens for yaks. Aminoglycosides and fluoroquinolones are frequently used medications for the treatment of M. bovis. Drug-resistant strains were inevitable with the abuse of antibiotics.
Jiaqiang Niu, Mingshuai Yan, Jinhua Xu, Yefen Xu, Zhenyu Chang, Suolang Sizhu   +5 more
doaj   +1 more source

Transporter and metabolizer gene polymorphisms affect fluoroquinolone pharmacokinetic parameters

Frontiers in Pharmacology, 2022
Tuberculosis (TB) is an infectious disease that occurs globally. Treatment of TB has been hindered by problems with multidrug-resistant strains (MDR-TB). Fluoroquinolones are one of the main drugs used for the treatment of MDR-TB.
Nurul Annisa, Nurul Annisa, Melisa I. Barliana, Melisa I. Barliana, Prayudi Santoso, Rovina Ruslami   +5 more
doaj   +1 more source

The incidence of collagen-associated adverse events in pediatric population with the use of fluoroquinolones: a nationwide cohort study in Taiwan

BMC Pediatrics, 2020
Background To evaluate the safety of using fluoroquinolones in pediatric population in Taiwan. Methods Patients aged 0~18 years old with fluoroquinolones prescriptions ≥5 consecutive days during year 2000 to 2013 were selected from the National Health ...
Pei-Han Yu, Chih-Fen Hu, Jen-Wei Liu, Chi-Hsiang Chung, Yong-Chen Chen, Chien-An Sun, Wu-Chien Chien   +6 more
doaj   +1 more source