Results 11 to 20 of about 72,300 (203)
Fluoroquinolones and Biofilm: A Narrative Review [PDF]
PharmaceuticalsBackground: Biofilm-associated infections frequently span multiple body sites and represent a significant clinical challenge, often requiring a multidisciplinary approach involving surgery and antimicrobial therapy.
Nicholas Geremia +12 more
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Repositioning of Fluoroquinolones: A New Approach in Antitumor Therapy [PDF]
BiologyFluoroquinolones are known for their antibacterial properties, but recent research has revealed their potential to inhibit the growth and proliferation of cancer cells.
Jeferson Ricardo da Silva +4 more
doaj +2 more sources
Fluoroquinolone Mannich bases as promising biologically beneficial molecules [PDF]
Minia Journal of Medical Research, 2021 Mannich bases, a structurally heterogeneous aminomethyl functionality, found numerous applicationsin medicinal chemistry field. Fluoroquinolones-Mannich bases here is discussed, with prominence onthe correlation between structure and biological activity ...
Mohamed Abdel-Aziz +3 more
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Heliyon, 2023 Background: Tuberculosis (TB) is an epidemic disease in Thailand. Fluoroquinolones are used to treat TB and have a lengthy treatment course. Therefore, many patients may have adverse effects from these medications.
Jirarat Chongboonwatana +2 more
doaj +1 more source
Recent Strategies in Design of Antitumor and Antibacterial Fluoroquinolones [PDF]
Journal of Advanced Biomedical and Pharmaceutical Sciences, 2021 Fluoroquinolones are known widely used synthetic antibacterial agents. Generally, there were some obstacles associated with their therapeutic use.
Mohamed Samir +4 more
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background Fluoroquinolones are first‐line antibiotics recommended for the treatment of complicated urinary tract infections (UTIs), with frequent reports of adverse effects of aortic aneurysm (AA) and aortic dissection (AD).
Yin‐Yang Chen +6 more
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Fluoroquinolones’ Biological Activities against Laboratory Microbes and Cancer Cell Lines
Molecules, 2022 Development of novel derivatives to rein in and fight bacteria have never been more demanding, as microbial resistance strains are alarmingly increasing.
Ghadeer A. R. Y. Suaifan +2 more
doaj +1 more source
Cardiotoxicity of fluoroquinolones [PDF]
Journal of Antimicrobial Chemotherapy, 2002 Currently marketed fluoroquinolones enjoy an admirable safety profile that is not matched by any other antibiotic group. The widespread use of fluoroquinolones in the elderly, who are susceptible to cardiac arrhythmias because of underlying heart diseases, metabolic derangement and use of anti-arrhythmic agents and other medications that prolong the QT
Ethan, Rubinstein, John, Camm
openaire +2 more sources
Frontiers in Veterinary Science, 2022 Mycoplasma bovis (M. bovis) is one of the important pathogens for yaks. Aminoglycosides and fluoroquinolones are frequently used medications for the treatment of M. bovis. Drug-resistant strains were inevitable with the abuse of antibiotics.
Jiaqiang Niu +5 more
doaj +1 more source
Environmental contamination by fluoroquinolones [PDF]
, 2014 Over the past few decades, a high number of pharmaceuticals have been detected in surface, ground and drinking waters. This contamination comes from domestic sewage, livestock, hospitals and chemical-pharmaceutical industries.
Teixeira, Antonio Carlos Silva Costa +7 more
core +2 more sources