Results 71 to 80 of about 34,906 (202)

The Mycobacterium tuberculosis Rv0132c Gene Product Mtb‐FGD2 Can Act as an F420‐Dependent Glucose Dehydrogenase

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 9, Page 1610-1627, September 2026.
ABSTRACT The role of the cell envelope‐associated Rv0132c/FGD2 from Mycobacterium tuberculosis has long been a subject of debate. Importantly, FGD2 is found only in pathogenic mycobacteria, making it a potential drug target. While some suggest it functions as a glucose‐6‐phosphate dehydrogenase, others propose it acts instead as an F420‐dependent ...
Adewale V. Aderemi, Matthew Snee, Richard B. Tunnicliffe, Linus O. Johanissen, Matthew J. Cliff, Colin W. Levy, Derren J. Heyes, Marina Golovanova, Thomas A. Jowitt, Sam Hay, Andrew W. Munro, Jonathan P. Waltho, David Leys   +12 more
wiley   +1 more source

Prevalence and Characteristics of Salmonella spp. by Production Stage in Integrated Broiler Operations in Korea

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Vertically integrated broiler production systems may facilitate the dissemination of Salmonella throughout the production chain. This study demonstrates that Salmonella persists and spreads across all stages of integrated broiler production, highlighting the need for rigorous biosecurity, hygiene and continuous monitoring throughout the entire ...
Hyeong Jeong Choi, Young Ju Lee
wiley   +1 more source

Synergistic Mechanism Between Ir–Phosphinito Catalyst and HFIP Enables Asymmetric Hydrogenation of Ketones Under Acidic Conditions

Advanced Synthesis &Catalysis, Volume 368, Issue 15, 1 August 2026.
A cooperative mechanism between a phosphinito Ir complex and HFIP provides a low‐energy pathway for hydrogen activation. This allowed the development of a highly efficient catalytic system for the hydrogenation of ketones that operates under acidic conditions, enabling the reduction of substrates containing phenols and carboxylic acids with no added ...
Martí Sidro, Agustí Lledós, María Vicent‐Morales, Jordi Benet‐Buchholz, Giuseppe Sciortino, Antoni Riera, Xavier Verdaguer   +6 more
wiley   +1 more source

Quinolone-resistant Campylobacter Infections in Denmark: Risk Factors and Clinical Consequences

Emerging Infectious Diseases, 2004
We integrated data on quinolone and macrolide susceptibility patterns with epidemiologic and typing data from Campylobacter jejuni and C. coli infections in two Danish counties.
Jørgen Engberg, Jakob Neimann, Eva Møller Nielsen, Frank Møller Aarestrup, Vivian Fussing   +4 more
doaj   +1 more source

Synthesis of 3-Carboxy-6-sulfamoylquinolones and Mefloquine-Based Compounds as Panx1 Blockers: Molecular Docking, Electrophysiological and Cell Culture Studies

Molecules
The membrane channel protein Panx1 is a promising therapeutic target since its involvement was demonstrated in a variety of pathologies such as neuropathic pain, ischemic stroke and cancer.
Letizia Crocetti, Maria Paola Giovannoni, Tengis S. Pavlov, Veniamin Ivanov, Fabrizio Melani, Gabriella Guerrini   +5 more
doaj   +1 more source

Detection of fluoroquinolone residues in milk using Yersinia spp. strains: towards better sensitivity for flumequine determination

Journal of Veterinary Research, 2017
Introduction: Plate diffusion methods play an important role in the monitoring system for antimicrobial agents in raw materials and foodstuffs of animal origin. The aim of this work was to select a Yersinia spp.
Navrátilová Pavlína, Vyhnálková Jana, Vorlová Lenka   +2 more
doaj   +1 more source

Drug-resistant Escherichia coli, Rural Idaho

Emerging Infectious Diseases, 2005
Stool carriage of drug-resistant Escherichia coli in home-living residents of a rural community was examined. Carriage of nalidixic acid–resistant E. coli was associated with recent use of antimicrobial agents in the household.
Elizabeth L. Hannah, Frederick J. Angulo, James R. Johnson, Bassam Haddadin, Jacquelyn Williamson, Matthew H. Samore   +5 more
doaj   +1 more source

Endogenous melatonin partial metabolic clearance as a potential endogenous marker of CYP1A2 activity

British Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2899-2908, August 2026.
Aims Cytochrome P450 1A2 (CYP1A2) exhibits substantial interindividual variability, necessitating appropriate phenotyping strategies for personalized pharmacotherapy. This study evaluated endogenous melatonin partial metabolic clearance (CLm(MEL)), calculated from urinary 6‐hydroxymelatonin (6‐O‐MEL) excretion and plasma melatonin (MEL) exposure, as a ...
Akitomo Yokokawa, Hayato Shimazaki, Shunji Igarashi, Yoshiki Tagawa, Naoki Hisada, Hiromi Shibasaki   +5 more
wiley   +1 more source

Two Novel 1,4‐Naphthoquinone Derivatives as Potent Agents Against Multidrug‐Resistant Staphylococcus aureus and Pathogenic Gram‐Positive Bacteria

Drug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT Drug‐resistant bacteria such as Methicillin‐resistant Staphylococcus aureus (MRSA) and Quinolone‐resistant S. aureus (QRSA), are a growing problem, creating a need for the development of novel antimicrobial agents. In this study, we designed and synthesized two novel 1,4‐naphthoquinone derivatives, LHN‐1034 and LHN‐1035, and evaluated their ...
HyunChan Song, Haena Lee, Ji‐Hyun Yoon, Hyunkyung Choi, Hakwon Kim, Ki‐Young Kim   +5 more
wiley   +1 more source

The Impact of Oral‐Gut Microbiota Structure and Its Manipulation on RA Development and Management

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
(A) Schematic representation of oral–gut microbiota composition in health and rheumatoid arthritis (RA), highlighting the enrichment of beneficial microorganisms (green) under healthy conditions and the expansion of pathogenic microorganisms (orange) in RA‐associated dysbiosis.
Parisa Ahmadi, Mahmoud Mahmoudi, Sina Mozaffari‐Jovin, Ramiar Kamal Kheder, Tola Abdulsattar Faraj, Samaneh Mollazadeh, Jafar Hajavi, Hanieh Kolahdooz, Seyed‐Alireza Esmaeili   +8 more
wiley   +1 more source