Anti‐Tubercular Drug‐Induced Liver Injury: Current Understanding and Emerging Directions
ABSTRACT Most common adverse effect causing cessation of anti‐tubercular treatment (ATT) is drug‐induced liver injury (DILI) which is unpredictable due to its idiosyncratic nature. ATT is the most common cause of DILI and drug‐induced acute liver failure (ALF) in South East Asia.
Shubham Prasad +3 more
wiley +1 more source
Antimicrobial activity of BMS 284756, a novel des-fluoro (6) quinolone and seven fluoroquinolones against Streptococcus pneumoniae [PDF]
Louis D. Saravolatz +3 more
openalex +1 more source
Divergent Evolution and Local Establishment of Multidrug‐Resistant Shigella sonnei in China
• Evolutionary history and local establishment of Chinese Shigella sonnei are unclear. • Chinese S. sonnei developed into four clades and ONPG‐negative variants. • The antimicrobial resistance phenotype of Clade I was due to an IncB/O/K/Z plasmid. • Antimicrobial resistance of Clade II was due to IncFII and IncB/O/K/Z plasmids.
Kangkang Liu +26 more
wiley +1 more source
Modulators of Diacylglycerol Kinase Activity: A Review of Advances and Challenges
ABSTRACT Catalyzing the conversion of diacylglycerol (DAG) in phosphatidic acid (PA), diacylglycerol kinases (DGKs) play a pivotal role in all the physiological processes modulated by these two bioactive lipids, such as lipid metabolism and immune regulation.
Luisa Racca +2 more
wiley +1 more source
Benzo[b]thiophene‐1,3,4‐oxadizole and 1,2,4‐oxadiazole hybrids 9a–9l were tested against both antibacterial and anticancer, revealing interesting structure‐activity relationships. density functional theory calculations (DFTs) at the B3LYP/6–311++G (d,p).
Ravikumar Gupta Miriyala +5 more
wiley +1 more source
Mutations ingyrAandparCGenes and Plasmid-Mediated Quinolone Resistance in Non-typhoidSalmonellaIsolated from Pediatric Patients with Diarrhea in Seoul [PDF]
Young-Hee Jin +6 more
openalex +1 more source
Infected diabetic foot ulcer endangers patients with high amputation, disability, mortality risks, and heavy medical burdens. This review analyzes its pathogenic factors, the limitations of current treatments, the breakthroughs of responsive antimicrobial biomaterials, and the challenge of multifunctional biomaterial innovations for further developing ...
Yaqi Yao +8 more
wiley +1 more source
Discovery of N -quinazolinone-4-hydroxy-2-quinolone-3-carboxamides as DNA gyrase B-targeted antibacterial agents [PDF]
Wenjie Xue +11 more
openalex +1 more source
Antimicrobial resistance in various infectious agents poses a public health threat. Therefore, this study aimed to determine the antibiotic resistance profiles, biofilm formation abilities and molecular characterisation of colistin‐resistant Escherichia coli O157:H7 from cattle carcasses.
Mukaddes Barel +7 more
wiley +1 more source
DETERMINATION OF SOME ANTIBIOTICS OF QUINOLONE AND TETRACYCLINE GROUPS USING TLC
T. D. Smirnova +2 more
openalex +1 more source

