Results 61 to 70 of about 35,652 (256)

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

Conformational Snapshots of CydDC in a Native Lipid Bilayer Coupling Heme Transport to Antibiotic Resistance

Advanced Science, EarlyView.
Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang, Changbin Zhang, Mengyuan Lyu, Yongbo Luo, Jierou Zhang, Yujiao Chen, Lintao Luo, Wen Qiao, Xiangyangpeng Li, Yu Zhou, Zhongling Wei, Yuling Xiao, Qian Niu, Juan Zhou, Guanglin He, Binwu Ying, Zhaoming Su, Hao Chen, Xiaodi Tang, Haohao Dong   +19 more
wiley   +1 more source

Furfuryl Alcohol‐Driven Proton Supply Enables Efficient Photocatalytic H2O2 Production Beyond Water‐Based Systems

Advanced Science, EarlyView.
A ZnIn2S4–carbon dot heterojunction enables photocatalytic H2O2 production coupled with furfuryl alcohol oxidation. In this redox system, furfuryl alcohol acts as both the electron donor and oxidation substrate, producing furoic acid with 100% selectivity and 98% conversion while supporting efficient H2O2 generation with a solar‐to‐chemical conversion (
Pengfei Bai, Ning Li, Quan Zhou, Bin Liu, Xiangqian Fan, Lei Liu, Jingkai Lin, Weijie Ren, Shengliang Hu, Huayang Zhang   +9 more
wiley   +1 more source

Alternative strategies for eliminating hydrogen sulfide and methanethiol from wine: results and learnings

OENO One
Six different remediation procedures for removing hydrogen sulfide (H2S) and methanethiol (MeSH) from a small selection of wines have been studied.
Diego Sánchez-Gimeno, Eduardo Vela, Vicente Ferreira, Ignacio Ontañón   +3 more
doaj   +1 more source

Spatiotemporal Targeting Randle Cycle and Immune Checkpoint for Potent Antitumor Therapy

Advanced Science, EarlyView.
A glucose oxidase‐based nanogel (GOX‐NG) system using catechol‐functionalized alginate, exhibits enhanced tumor penetration, prolonged retention, and sustained glucose depletion in the tumor microenvironment. When combined with a fatty acid oxidation inhibitor, it implements dual metabolic suppression, thereby enhancing ROS‐induced immunogenic cell ...
Yuan Gao, Zijian Gong, Yixuan Fu, Jianan Zheng, Xiao Sang, Binglin Chen, Qinzhi Su, Weiping Gao, Fei Duan, Jinqi Wei, Xuliang Deng, Xinyu Liu   +11 more
wiley   +1 more source

Interfacial Water Coordination on Ruthenium Oxide Nanoparticles Confined Within Covalent Organic Framework and Its Effect on Electrochemical Nitrate Reduction

Advanced Science, EarlyView.
We demonstrate how oxygen‐deficient ruthenium oxide (RuOx) nanoparticles confined within covalent organic framework achieve highly efficient nitrate‐to‐ammonia conversion. Strong interaction between RuOx nanoparticles and COF results in modified interfacial hydrogen‐bond water network and adsorption of nitrogenous intermediates.
Yun Li, Xin Zhao, Arsenii S. Portniagin, Yuxuan Wu, Desui Chen, Haochen Liu, Andrey L. Rogach   +6 more
wiley   +1 more source

Design and synthesis of propellane derivatives and oxa-bowls via ring-rearrangement metathesis as a key step

Beilstein Journal of Organic Chemistry, 2015
Various intricate propellane derivatives and oxa-bowls have been synthesized via a ring-rearrangement metathesis (RRM) as a key step starting from readily accessible starting materials such as p-benzoquinone, 1,4-naphthoquinone and 1,4-anthraquinone.
Sambasivarao Kotha, Rama Gunta
doaj   +1 more source

Nano‐Backpack Engineered Probiotics with Reactive Oxygen Species–Responsive Tungsten Release for Synergistic Therapy of Inflammatory Bowel Disease

Advanced Science, EarlyView.
An integrated probiotic system is engineered to execute a programmed therapeutic cascade against inflammatory bowel disease. Upon pathological signals, the system sequentially performs ROS scavenging, tungsten release, and selective pathogen suppression, thereby breaking the oxidative stress–dysbiosis cycle to remodel gut microbiota and reinforce ...
Yang Yang, Liucan Wang, Guoqing Chen, Yuanling Zhang, Jiarui Shi, Wenzhe Fan, Min Yu, Jixi Zhang, Hua Yang   +8 more
wiley   +1 more source

Unveiling Activation Process of C═N Cathode for High‐Performing Zinc‐Organic Batteries

Advanced Science, EarlyView.
A high‐performance organic cathode of DPPT has been designed for aqueous zinc‐ion batteries (ZIBs), showing ultralong cycle life of 45 000 cycles. Besides, flexible DPPT ZIBs with stable capacity are applied in wearable NH3 sensors. Notably, the activation mechanism of the transformation of DPPT‐eight proton into DPPT is proposed and proved which ...
Xiaodong Geng, Zhangyu Wang, Weiyao Bi, Qian Zhao, Hongting Ma, Kai Yang, Ying Liu, Zhiqian Li, Qinghua Deng, Dan Zhao, Yuqian Jiang, Nan Zhu   +11 more
wiley   +1 more source

RATE CONSTANTS FUR THE ELECTRODE REACTIONS OF QUINONES IN CHLOROFORM: THE DEPENDENCE ON ELECTRODE MAmRIAL,S AND APPARENT STANDARD POENTIALS [PDF]

Journal of Sciences, Islamic Republic of Iran, 1996
The reduction process for some quinones has been studid by cyclic voltammeby, rotating disk electrode voltammetry and chronopotentiometry in chloroform at platinum, gold and glassy carbon electrodes using tetrabutylmonium perchlorate (TB AP) as ...
doaj