Results 101 to 110 of about 24,735 (283)

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Minuscule reverse plane partitions via quiver representations

open access: yes, 2018
A nilpotent endomorphism of a quiver representation induces a linear transformation on the vector space at each vertex. Generically among all nilpotent endomorphisms, there is a well-defined Jordan form for these linear transformations, which is an ...
Garver, Alexander   +2 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Asymptotic degeneration of representations of quivers

open access: yesCommentarii Mathematici Helvetici, 2000
We define asymptotic degeneration of nilpotent representations of an arbitrary finite quiver, using large tensor powers and small direct sums, and characterize this notion by a simple and effective criterion.
openaire   +4 more sources

QUIVER REPRESENTATIONS RESPECTING A QUIVER AUTOMORPHISM: A GENERALISATION OF A THEOREM OF KAC [PDF]

open access: yesJournal of the London Mathematical Society, 2004
We consider quiver representations respecting a quiver automorphism and show that the dimension vectors of the indecomposables are precisely the positive roots of an associated symmetrisable Kac-Moody Lie algebra. Moreover, every such Lie algebra arises in this way. We also discuss the relationship with species of valued quivers over finite fields.
openaire   +3 more sources

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Skyrme and Faddeev models in the low-energy limit of 4d Yang–Mills–Higgs theories

open access: yesNuclear Physics B, 2019
Firstly, we consider U(Nc) Yang–Mills gauge theory on R3,1 with Nf>Nc flavours of scalar fields in the fundamental representation of U(Nc). The moduli space of vacua is the Grassmannian manifold Gr(Nc,Nf).
Olaf Lechtenfeld, Alexander D. Popov
doaj   +1 more source

On the Morita Reduced Versions of Skew Group Algebras of Path Algebras

open access: yes, 2018
Let R be the skew group algebra of a finite group acting on the path algebra of a quiver. This article develops both theoretical and practical methods to do computations in the Morita reduced algebra associated to R.
Meur, Patrick Le
core  

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati   +10 more
wiley   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy