Results 71 to 80 of about 24,735 (283)

Star-triangle type relations from 2d N $$ \mathcal{N} $$ = (0, 2) USp(2N) dualities

Journal of High Energy Physics, 2021
Inspired by the gauge/YBE correspondence this paper derives some star-triangle type relations from dualities in 2d N $$ \mathcal{N} $$ = (0, 2) USp(2N) supersymmetric quiver gauge theories. To be precise, we study two cases.
J. de-la-Cruz-Moreno, H. García-Compeán   +1 more
doaj   +1 more source

Quiver grassmannians, quiver varieties and the preprojective algebra

, 2014
Quivers play an important role in the representation theory of algebras, with a key ingredient being the path algebra and the preprojective algebra. Quiver grassmannians are varieties of submodules of a fixed module of the path or preprojective algebra ...
Alistair Savage, Anderson, Auslander, Deng, Geiss, Hartshorne, Jategaonkar, Lam, McConnell, Nakajima, Peter Tingley, Reiten, Ringel, Savage, Shipman   +14 more
core   +1 more source

Recovering Quivers from Derived Quiver Representations [PDF]

Communications in Algebra, 2013
We compute Balmer's prime spectrum for the derived category of quiver representations for a finite ordered quiver with the vertex-wise tensor product and show that it does not recover the quiver. We then associate an algebra to every k-linear triangulated tensor category and show that the path algebra can be recovered in this way.
Sierra, Susan, Liu, Yu-Han
openaire   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

BPS Wilson loop in N $$ \mathcal{N} $$ = 2 superconformal SU(N) “orientifold” gauge theory and weak-strong coupling interpolation

Journal of High Energy Physics, 2021
We consider the expectation value W $$ \left\langle \mathcal{W}\right\rangle $$ of the circular BPS Wilson loop in N $$ \mathcal{N} $$ = 2 superconformal SU(N) gauge theory containing a vector multiplet coupled to two hypermultiplets in rank-2 symmetric ...
M. Beccaria, G. V. Dunne, A. A. Tseytlin
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Wall-crossing effects on quiver BPS algebras

Journal of High Energy Physics
BPS states in supersymmetric theories can admit additional algebro-geometric structures in their spectra, described as quiver Yangian algebras. Equivariant fixed points on the quiver variety are interpreted as vectors populating a representation module ...
Dmitry Galakhov, Alexei Morozov, Nikita Tselousov   +2 more
doaj   +1 more source

Nekrasov and Argyres–Douglas theories in spherical Hecke algebra representation

Nuclear Physics B, 2017
AGT conjecture connects Nekrasov instanton partition function of 4D quiver gauge theory with 2D Liouville conformal blocks. We re-investigate this connection using the central extension of spherical Hecke algebra in q-coordinate representation, q being ...
Chaiho Rim, Hong Zhang
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source