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Generation of Quorum Quenching Antibodies
2010The exchange of information within and among bacterial populations using small diffusible molecules has been termed "quorum sensing" (QS). Due to the extracellular distribution of the QS autoinducer molecules and the evolutionary highly conserved nature of signaling components, microbial QS systems represent an excellent target for anti-infective ...
Gunnar F, Kaufmann +4 more
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Towards quorum-quenching catalytic antibodies
Chem. Commun., 2009The development of a novel method to attenuate bacterial virulence is reported, which is based upon the use of designed transition-state analogues to select human catalytic antibodies capable of degrading bacterial quorum-sensing molecules.
Prashant B, Kapadnis +5 more
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Quorum‐sensing quenching by rhizobacterial volatiles
Environmental Microbiology Reports, 2011Summary We show that volatile organic compounds (VOCs) produced by rhizospheric strains Pseudomonas fluorescens B‐4117 and Serratia plymuthica IC1270 may act as inhibitors of the cell–cell communication quorum‐sensing (QS) network ...
Leonid, Chernin +6 more
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Quorum Sensing and Quorum Quenching: The Yin and Yang of Bacterial Communication
ChemBioChem, 2009Vibrio fischeri is a remarkable Gram-negative marine bacterium. First, it emits light when it colonizes the fish or squid organs dedicated to this purpose. Second, it turns this light on when entering these organs and switches it off when leaving them. In V.
Stéphane, Uroz +2 more
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Role of quorum sensing and quorum quenching in anaerobic digestion: A scoping review
Environmental Research, 2023Anaerobic digestion (AD) is a biological process that employs anaerobic microorganisms to degrade organic material, yielding biogas and biofertilizers. Understanding quorum sensing (QS) signaling in mixed microbial systems provides valuable insights into microbial behavior and functions. This review aims to examine recent studies on the roles of QS and
Parthiban Anburajan +7 more
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Quorum Quenching for Sustainable Environment
2021Quorum quenching is the process that prevents quorum sensing through the disruption of signalling cascade and bacterial communication among themselves mediated by the degradation of the signalling molecules. Therefore, quorum quenching has a considerable contribution in the negative regulation of threatening diseases and eventually increasing soil ...
Sumira Malik +6 more
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Quorum Sensing and Quorum Quenching Facebook of Microbial World
International Journal of Scientific Research, 2012Dental Plaque is an example of biofilm leading to periodontal disease and dental caries. Many Gram-positive and Gram-negative bacteria communicate using small diffusible signal molecules called autoinducers. This process, known as quorum sensing, links cell density to the expression of genes as diverse as those associated with virulence fac- tors ...
Dr. Babita Sahu +5 more
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Quorum Sensing and Quorum Quenching in Soil Ecosystems
2010Several bacteria originating from soil ecosystems have evolved the ability to regulate gene expression as a function of their cell density, a phenomenon called quorum sensing (QS). To do so bacteria communicate via the production and sensing of signal molecules. The most common class of signals clusters N-acyl homoserine lactones (AHL) molecules.
Yves Dessaux +2 more
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Current Opinion in Pharmacology, 2013
With the emergence of microbial pathogens increasingly resistant against commonly used antibiotics, new treatment strategies are desperately needed. Bacterial quorum sensing has attracted a lot of attention over the last decade as a potential new target for antimicrobial therapy.
Jie, Zhu, Gunnar F, Kaufmann
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With the emergence of microbial pathogens increasingly resistant against commonly used antibiotics, new treatment strategies are desperately needed. Bacterial quorum sensing has attracted a lot of attention over the last decade as a potential new target for antimicrobial therapy.
Jie, Zhu, Gunnar F, Kaufmann
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Quorum sensing and quorum-quenching enzymes.
Journal of microbiology (Seoul, Korea), 2005To gain maximal benefit in a competitive environment, single-celled bacteria have adopted a community genetic regulatory mechanism, known as quorum sensing (QS). Many bacteria use QS signaling systems to synchronize target gene expression and coordinate biological activities among a local population.
Yi-Hu, Dong, Lian-Hui, Zhang
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