Results 1 to 10 of about 6,201 (226)

High yield expression of an AHL-lactonase from Bacillus sp. B546 in Pichia pastoris and its application to reduce Aeromonas hydrophila mortality in aquaculture [PDF]

Microbial Cell Factories, 2010
Background Aeromonas hydrophila is a serious pathogen and can cause hemorrhagic septicemia in fish. To control this disease, antibiotics and chemicals are widely used which can consequently result in "superbugs" and chemical accumulation in the food ...
Bai Yingguo, Cao Yanan, Zhou Zhigang, Chen Ruidong, Yao Bin   +4 more
doaj   +4 more sources

Effects of combined oral contraceptives and metformin on paraoxonase 1 lactonase activity and status in patients with polycystic ovary syndrome and insulin resistance [PDF]

Frontiers in Endocrinology
ObjectiveTo investigate the effects of combined oral contraceptives (COCs) and metformin treatment on the lactonase activity and status of paraoxonase 1 (PON1), and oxidative stress levels in patients with polycystic ovary syndrome (PCOS) and insulin ...
Jiagui Liang, Jiagui Liang, Qiuyi Wang, Qiuyi Wang, Dong Liu, Dong Liu, Lukanxuan Wu, Lukanxuan Wu, Xinyu Qiao, Xinyu Qiao, Ruiying Wang, Ruiying Wang, Yuchan Zhong, Yuchan Zhong, Wenjie Bo, Wenjie Bo, Huiqiao Lai, Huiqiao Lai, Ping Fan, Wei Huang, Wei Huang   +20 more
doaj   +2 more sources

Quorum quenching by endophytic Bacillus cereus AL1: a lactonase-based anti-virulence strategy against Pseudomonas aeruginosa [PDF]

BMC Microbiology
Background Pseudomonas aeruginosa infections are often challenging to treat due to multiple drug resistance, besides the development of biofilms and a plethora of virulence factors regulated by quorum sensing.
Alaa A. Fawzy, Marwa M. Raafat, R. Mahmoud, Omneya M. Helmy   +3 more
doaj   +2 more sources

Plasma levels of adhesion molecules are elevated in dermatomyositis-interstitial lung disease and associated with low paraoxonase-1 activity [PDF]

Arthritis Research & Therapy
Objective To evaluate circulating levels of intercellular cell adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) in patients with dermatomyositis (DM) and DM associated interstitial lung disease (DM-ILD).
Sangmee Sharon Bae, Ani Shahbazian, Jennifer Wang, Daniela Markovic, Tiffany De Leon, Yuna Lee, Srinivasa T. Reddy, Christina Charles-Schoeman   +7 more
doaj   +2 more sources

In Silico Identification of Potential Biomarker-Binding Proteins for Noninvasive Diagnosis of Buruli Ulcer Disease [PDF]

Bioinformatics and Biology Insights
Buruli ulcer (BU) is a necrotizing skin disease caused by Mycobacterium ulcerans that produces a virulent lipid toxin, mycolactone, which is detectable in urine.
Erica A Akanko, Clement Agoni, George Hanson, Henrietta Esi Mensah-Brown, Kwabena Kan-Dapaah, Claude Fiifi Hayford, Cletus Fiifi Adams, Lydia Mosi, Samuel K Kwofie   +8 more
doaj   +2 more sources

Sensitive Assay for the Lactonase Activity of Serum Paraoxonase 1 (PON1) by Harnessing the Fluorescence Turn-On Characteristics of Bioorthogonally Synthesized and Geometrically Controlled Chemical Probes

Molecules, 2022
The lactonase activity of paraoxonase 1 (PON1) has a crucial antiatherogenic function, and also serves as an important biochemical marker in human blood because the aberrant lactonase activity of PON1 is a key indicator for a number of diverse human ...
Bo-Kai Fang, Chia-Yen Dai, Scott Severance, Chi-Ching Hwang, Chien-Hui Huang, Sin-Yu Hou, Bao-Lin Yeh, Ming-Mao Gong, Yun-Hao Chou, Jeh-Jeng Wang, Tzu-Pin Wang   +10 more
doaj   +1 more source

DJ-1 interacts with and regulates paraoxonase-2, an enzyme critical for neuronal survival in response to oxidative stress. [PDF]

, 2014
Loss-of-function mutations in DJ-1 (PARK7) gene account for about 1% of all familial Parkinson's disease (PD). While its physiological function(s) are not completely clear, DJ-1 protects neurons against oxidative stress in both in vitro and in vivo ...
Aleyasin, Hossein, Bourquard, Noam, Callaghan, Steve, Figeys, Daniel, Huang, En, Irrcher, Isabella, Kim, Raymond H, Mak, Tak W, Park, David S, Parsanejad, Mohammad, Qu, Dianbo, Reddy, Srinivasa T, Rousseaux, Maxime WC, Slack, Ruth S, Vaillant, Dominique C, Zhang, Yi   +15 more
core   +6 more sources

Longitudinal changes of oxidative stress and PON1 lactonase activity and status in older pregnant women undergoing assisted reproductive technology: a prospective nested case-control study

Reproductive Biology and Endocrinology, 2023
Background Childbearing in women with advanced maternal age (AMA) has increased the need for artificial reproductive technology (ART). ART and oxidative stress are associated with many pregnancy complications.
Chenyu Jiang, Meng Chen, Yujie Wu, Huai Bai, Xinghui Liu, Ping Fan   +5 more
doaj   +1 more source

Serum Arylesterase, Paraoxonase, and Lactonase Activities and Paraoxonase-1 Concentrations in Morbidly Obese Patients and Their Relationship with Non-Alcoholic Steatohepatitis

Antioxidants, 2023
Paraoxonase-1 (PON1) is an antioxidant enzyme associated with high-density lipoproteins (HDL). Reduced serum PON1 activity is found in diseases marked by oxidative stress and inflammation, but its role in obesity remains unclear.
Helena Castañé, Andrea Jiménez-Franco, Cristian Martínez-Navidad, Cristina Placed-Gallego, Vicente Cambra-Cortés, Adelina-Miruna Perta, Marta París, Daniel del Castillo, Meritxell Arenas, Jordi Camps, Jorge Joven   +10 more
doaj   +1 more source

Use of Quorum Sensing Inhibition Strategies to Control Microfouling

Marine Drugs, 2021
Interfering with the quorum sensing bacterial communication systems has been proposed as a promising strategy to control bacterial biofilm formation, a key process in biofouling development. Appropriate in vitro biofilm-forming bacteria models are needed
Andrea Muras, Ana Parga, Celia Mayer, Ana Otero   +3 more
doaj   +1 more source