Caffeine Increases Apolipoprotein A-1 and Paraoxonase-1 but not Paraoxonase-3 Protein Levels in Human-Derived Liver (HepG2) Cells [PDF]
Background: Apolipoprotein A-1, paraoxonase-1 and paraoxonase-3 are antioxidant and anti-atherosclerotic structural high-density lipoprotein proteins that are mainly synthesized by the liver.
Gülben Sayılan Özgün +5 more
doaj +2 more sources
Bladder Cancer Chemosensitivity Is Affected by Paraoxonase-2 Expression
The goal of the current study was to identify potential roles of paraoxonase-2 in bladder carcinogenesis. T24 bladder cancer cells were transfected with plasmids inducing paraoxonase-2 silencing or overexpression. Upon the selection of clones stably down-
Andrea B Galosi +2 more
exaly +3 more sources
PON1 haplotypes show genotype-dependent associations with dysglycemia and metabolic liver risk beyond paraoxonase activity [PDF]
IntroductionParaoxonase 1 (PON1) is a liver-derived HDL-associated enzyme with key antioxidant functions implicated in cardiometabolic disease.
Laura Batista-Herrera +13 more
doaj +2 more sources
Preferential inhibition of paraoxonase activity of human paraoxonase 1 by negatively charged lipids
To determine the causes responsible for a preferential decrease of paraoxonase activity, which has been observed in the serum of patients with cardiovascular diseases, the inactivation or inhibition of paraoxonase 1 (PON1) by various endogenous factors ...
Dai-Eun Sok, Su Duy Nguyen
exaly +3 more sources
Study the levels of Leptin, and Adiponectin with Paraoxonase in Obese Individuals (male & female)
Obesity is a well-known risk factor of metabolic complications and cardiovascular disease. Associations between anthropometric measurements and fat distribution and risk factors for cardiovascular disease have been demonstrated in several populations.
Entedhar R. Sarhat
doaj +1 more source
Effect of Gluten-Free Diet on Serum Antioxidant Levels in Children with Celiac
Objective: Celiac disease (CD) is an inflammatory condition of the small intestine triggered by the consumption of gluten. A strict gluten-free diet (GFD) is the only treatment that can eliminate CD complications. It was aimed to evaluate the effect of a
Mehmet Ali Gül +5 more
doaj +1 more source
Role of oxidant-antioxidant enzymes in managing the cardiovascular risks in nephrotic syndrome patients [PDF]
Increased reactive oxygen species (ROS) in nephrotic syndrome (NS) are involved in the oxidation of membrane proteins, lipoproteins and several receptor molecules ultimately leading to their functional deficit.
Souparnika Sreelatha +3 more
doaj +1 more source
Current findings aimed to find out camel milk's effects on lipid metabolism, expression of the genes for antioxidant enzymes and paraoxonase-1 (PON-1) activity in rats fed diet-containing cholesterol 1%. Therefore, 30 rats were divided into three groups
Sabry M. El-Bahr +2 more
doaj +1 more source
Evaluation of Oxidative Stress Parameters and Antioxidant Status in Coronary Artery Disease Patients [PDF]
A surge in oxidative stress and weakened antioxidant defense contributes to the initiation and progression of Coronary Artery Diseases (CAD). The resultant burst in free radicals causes oxidation of lipoproteins mainly oxidized low-density lipoprotein ...
S Varadhan +3 more
doaj +1 more source
Evidence of Paraoxonases 1, 2, and 3 Expression in Human Ovarian Granulosa Cells
Increasing evidence suggests that the antioxidant paraoxonase proteins, PON1, PON2, and PON3, have a role in reproduction and may be synthesized by ovarian cells.
Irantzu Pérez-Ruiz +6 more
doaj +1 more source

