Results 1 to 10 of about 9,907 (172)
PON1 and Mediterranean Diet [PDF]
Nutrients, 2015 The Mediterranean diet has been proven to be highly effective in the prevention of cardiovascular diseases. Paraoxonase 1 (PON1) has been implicated in the development of those conditions, especially atherosclerosis. The present work describes a systematic review of current evidence supporting the influence of Mediterranean diet and its constituents on
José Manuel Lou-Bonafonte +2 more
exaly +7 more sources
Developmental Changes in PON1 Enzyme Activity in Young Children and Effects of PON1 Polymorphisms [PDF]
Environmental Health Perspectives, 2009 Paraoxonase 1 (PON1) is an enzyme that detoxifies activated organophosphorus pesticides (OPs) and is also involved in oxidative stress pathways.PON1 activity in newborns is lower than in adults, but the ontogeny of PON1 activity is poorly characterized in young children.
Kim Harley +2 more
exaly +6 more sources
Paraoxonase (PON1) Phenotype Is a Better Predictor of Vascular Disease Than Is PON1 192 or PON1 55 Genotype [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2000 Abstract —The paraoxonase (PON1) PON1-Q192R and PON1-L55M polymorphisms have been inconsistently associated with vascular disease. Plasma PON1 activity phenotypes vary markedly within genotypes and were, therefore, expected to add to the informativeness of genotype for predicting ...
G P, Jarvik +6 more
openaire +3 more sources
Effect of anaerobic training on serum paraoxonase 1 (PON1) activity and role of PON1-L55M polymorphism [PDF]
Kinesiologia Slovenica: scientific journal on sportParaoxonase (PON) enzyme family (paraoxonase 1, 2 and 3) has antiatherosclerotic properties. The decreased PON1 enzyme activity (EA), PON1 level and PON1-L55M polymorphism (PON1P) are risk factors for atherosclerosis. Effects of anaerobic training on PON1 levels and the role of PON1P are unclear.
Sevilmis, Ezgi +6 more
core +5 more sources
Effect of PON1 on dichlorvos toxicokinetics [PDF]
Emergency Medicine Journal, 2010 To provide toxicokinetic and clinical evidence of the hydrolytic effect of paraoxonase-1 (PON1) on acute organophosphate poisoning in rats.40 male Wistar rats were randomised into four equal groups. Dichlorvos administration group (A group) underwent dichlorvos injection (dissolved in corn oil) using intraperitoneal (ip) dose of 10 mg/kg.
Wang, Na-Na +4 more
openaire +2 more sources
PON1 multitasks to protect health [PDF]
Proceedings of the National Academy of Sciences, 2008 The enzyme paraoxonase 1 (PON1) is an excellent example of a multitasking protein, displaying at least two very important functions: hydrolysis of organophosphorus (OP) anticholinesterases and prevention of oxidation of low density lipoproteins (LDLs) and high density lipoproteins (HDLs).
openaire +2 more sources
Paraoxonase-1 (PON1) promoter region polymorphisms, serum PON1 status and coronary heart disease
Archives of Medical Science, 2013 Serum paraoxonase-1 (PON1) retards the oxidation of low-density lipoprotein and cell membranes and is atheroprotective. Polymorphisms in the promoter region of the PON1 gene have been shown to affect serum PON1 levels and have been related to the presence of coronary heart disease (CHD) in some studies. However, contradictory results have been reported
Mackness, Bharti +2 more
openaire +2 more sources
Paraoxonase (PON1) and polymorphisms of PON1 gene
The Journal of Japan Atherosclerosis Society, 2000 Tadashi SUEIRO +4 more
openaire +2 more sources
In vivo (Athens, Greece), 2009 Ovarian cancer is the leading cause of death due to gynecological malignancies among women. Oxidative stress is potentially harmful to cells and reactive oxygen species are known to be involved in the initiation and progression of cancer. Paraoxonase (PON1) is an antioxidative enzyme, which eliminates lipid peroxides. PON1 has two common polymorphisms (
Aytaç, Arpaci +4 more
openaire +1 more source