Results 11 to 20 of about 16,258 (219)

Do PON1–Q192R and PON1–L55M polymorphisms modify the effects of hypoxic training on paraoxonase and arylesterase activity?

Journal of Sport and Health Science, 2023
Background: Low levels of antioxidant paraoxonase 1 (PON1) enzyme activity, PON1–Q192R polymorphism (a glutamine (Q) to arginine (R) substitution at position 192), PON1–L55M polymorphism (a leucine (L) to methionine (M) substitution at position 55), and ...
Oya Yigittürk, Faruk Turgay, Servet Kızıldağ, Dua Özsoylu, Görkem Aybars Balcı   +4 more
doaj   +2 more sources

PON1 and Mediterranean Diet [PDF]

Nutrients, 2015
The Mediterranean diet has been proven to be highly effective in the prevention of cardiovascular diseases. Paraoxonase 1 (PON1) has been implicated in the development of those conditions, especially atherosclerosis.
J. M. Lou-Bonafonte, C. Gabás-Rivera, M. Navarro, J. Osada   +3 more
semanticscholar   +2 more sources

Evaluation of a Gene–Environment Interaction of PON1 and Low-Level Nerve Agent Exposure with Gulf War Illness: A Prevalence Case–Control Study Drawn from the U.S. Military Health Survey’s National Population Sample

Environmental Health Perspectives, 2022
Background: Consensus on the etiology of 1991 Gulf War illness (GWI) has been limited by lack of objective individual-level environmental exposure information and assumed recall bias.
R. Haley, Gerald Kramer, Jun-Hui Xiao, Jill A. Dever, J. Teiber   +4 more
semanticscholar   +1 more source

The Antioxidant Enzyme PON1: A Potential Prognostic Predictor of Acute Ischemic Stroke

Oxidative Medicine and Cellular Longevity, 2021
Objective Paraoxonase 1 (PON1) is an antioxidant enzyme, which has been proved to be involved in the pathophysiological process of oxidative stress and various neurological diseases in recent years.
Yu-Zhen Xu, Kai Wang, Qian Wang, Yi-Hong Ma, Xue-Yuan Liu   +4 more
semanticscholar   +1 more source

Comparison of DNA methylation measurements from EPIC BeadChip and SeqCap targeted bisulphite sequencing in PON1 and nine additional candidate genes

Epigenetics, 2022
Epigenome-wide association studies (EWAS) are widely implemented in epidemiology, and the Illumina HumanMethylationEPIC BeadChip (EPIC) DNA microarray is the most-used technology. Recently, next-generation sequencing (NGS)-based methods, which assess DNA
Dennis Khodasevich, Anna R. Smith, Karen Huen, Brenda Eskenazi, Andres Cardenas, Nina Holland   +5 more
doaj   +1 more source

Vutiglabridin Modulates Paraoxonase 1 and Ameliorates Diet-Induced Obesity in Hyperlipidemic Mice

Biomolecules, 2023
Vutiglabridin is a clinical-stage synthetic small molecule that is being developed for the treatment of obesity and its target proteins have not been fully identified.
Dawoud Sulaiman, Leo Sungwong Choi, Hyeong Min Lee, Jaejin Shin, Dong Hwan Kim, Keun Woo Lee, Pierre Eftekhari, Angélique Quartier, Hyung Soon Park, Srinivasa T. Reddy   +9 more
doaj   +1 more source

Associations between PON1 enzyme activities in human ovarian follicular fluid and serum specimens. [PDF]

PLoS ONE, 2017
The importance of high-density lipoprotein (HDL) particle components to reproduction is increasingly recognized, including the constituent paraoxonase 1 (PON1).
Keewan Kim, Michael S Bloom, Victor Y Fujimoto, Richard W Browne   +3 more
doaj   +1 more source

Paraoxonase-1 Facilitates PRRSV Replication by Interacting with Viral Nonstructural Protein-9 and Inhibiting Type I Interferon Pathway

Viruses, 2022
Paraoxonase-1 (PON1), an esterase with specifically paraoxonase activity, has been proven to be involved in inflammation and infection. Porcine reproductive and respiratory syndrome virus (PRRSV) is still a major concern in pigs and causes severe ...
Lin Zhang, Yu Pan, Yunfei Xu, Wenli Zhang, Wenjie Ma, Yassein M. Ibrahim, Gebremeskel Mamu Werid, He Zhang, Changyou Xia, Ping Wei, Hongyan Chen, Yue Wang   +11 more
doaj   +1 more source

Role of Paraoxonase-1 (Q192R) Gene Polymorphism in Coronary Artery Disease in Saudi Arabian Population [PDF]

JLUMHS, 2019
OBJECTIVES: To assess the prevalence and dissemination of PON1 Q192R polymorphism and PON1 activities in CAD patients and controls. METHODOLOGY: A case control study, conducted from October 2016 to December 2017.
Samir Abdulkarim Alharbi , Ramprasad Nagarajrao, Abdullah Habbab Alharbi   +2 more
doaj   +1 more source

Serum PON1 as a biomarker for the estimation of microvascular invasion in hepatocellular carcinoma

Annals of Translational Medicine, 2020
Background Microvascular invasion (MVI) is considered as one of the most powerful prognostic factors in hepatocellular carcinoma (HCC). Currently, it could only be diagnosed by post-operative histological examination.
Guang-Yu Ding, Xiao-Dong Zhu, Yuan Ji, G. Shi, Ying-Hao Shen, Jian Zhou, Jia Fan, Hui-Chuan Sun, Cheng Huang   +8 more
semanticscholar   +1 more source