Results 11 to 20 of about 20,745 (266)

PON1 and Mediterranean Diet [PDF]

open access: yesNutrients, 2015
The Mediterranean diet has been proven to be highly effective in the prevention of cardiovascular diseases. Paraoxonase 1 (PON1) has been implicated in the development of those conditions, especially atherosclerosis.
J. M. Lou-Bonafonte   +3 more
semanticscholar   +5 more sources

Serum paraoxonase 1 (PON1) measurement: an update [PDF]

open access: yesBMC Veterinary Research, 2014
Paraoxonase 1 (PON1) is a widely studied enzyme based on its protective role against poisoning by organophosphate (OP) metabolites of specific OP insecticides and in vascular disease, as well as its use as biomarker of diseases involving oxidative stress,
J. Cerón   +2 more
semanticscholar   +3 more sources

Quantifying PON1 on HDL with nanoparticle-gated electrokinetic membrane sensor for accurate cardiovascular risk assessment

open access: yesNature Communications, 2023
Cardiovascular disease-related deaths (one-third of global deaths) can be reduced with a simple screening test for better biomarkers than the current lipid and lipoprotein profiles.
Sonu Kumar   +4 more
semanticscholar   +1 more source

Evaluation of a Gene–Environment Interaction of PON1 and Low-Level Nerve Agent Exposure with Gulf War Illness: A Prevalence Case–Control Study Drawn from the U.S. Military Health Survey’s National Population Sample

open access: yesEnvironmental Health Perspectives, 2022
Background: Consensus on the etiology of 1991 Gulf War illness (GWI) has been limited by lack of objective individual-level environmental exposure information and assumed recall bias.
R. Haley   +4 more
semanticscholar   +1 more source

The Antioxidant Enzyme PON1: A Potential Prognostic Predictor of Acute Ischemic Stroke

open access: yesOxidative Medicine and Cellular Longevity, 2021
Objective Paraoxonase 1 (PON1) is an antioxidant enzyme, which has been proved to be involved in the pathophysiological process of oxidative stress and various neurological diseases in recent years.
Yuzhen Xu   +4 more
semanticscholar   +1 more source

Serum PON1 as a biomarker for the estimation of microvascular invasion in hepatocellular carcinoma

open access: yesAnnals of Translational Medicine, 2020
Background Microvascular invasion (MVI) is considered as one of the most powerful prognostic factors in hepatocellular carcinoma (HCC). Currently, it could only be diagnosed by post-operative histological examination.
Guangyu Ding   +8 more
semanticscholar   +1 more source

Role of Paraoxonase-1 (Q192R) Gene Polymorphism in Coronary Artery Disease in Saudi Arabian Population [PDF]

open access: yesJLUMHS, 2019
OBJECTIVES: To assess the prevalence and dissemination of PON1 Q192R polymorphism and PON1 activities in CAD patients and controls. METHODOLOGY: A case control study, conducted from October 2016 to December 2017.
Samir Abdulkarim Alharbi   +2 more
doaj   +1 more source

Paraoxonase 1 gene polymorphisms in lipid oxidation and atherosclerosis development

open access: yesFrontiers in Genetics, 2022
Paraoxonase 1 (PON1) is calcium-dependent aryldialkylphosphatase, thought to possess; anti-oxidant, anti-adhesion, anti-inflammatory, anti-thrombosis and anti-apoptosis effects, as well as lipid-modifying properties.
Marija Vavlukis   +4 more
doaj   +1 more source

A Multi-Omics Analysis of PON1 Lactonase Activity in Relation to Human Health and Disease

open access: yesOmics, 2020
Paraoxonase 1 (PON1) enzyme has antioxidative properties and is present in mammalian blood and several other body fluids. In blood, PON1 is usually integrated into the high-density lipoprotein (HDL) cholesterol.
Boštjan Petrič, T. Kunej, A. Bavec
semanticscholar   +1 more source

Do PON1–Q192R and PON1–L55M polymorphisms modify the effects of hypoxic training on paraoxonase and arylesterase activity?

open access: yesJournal of Sport and Health Science, 2023
Background: Low levels of antioxidant paraoxonase 1 (PON1) enzyme activity, PON1–Q192R polymorphism (a glutamine (Q) to arginine (R) substitution at position 192), PON1–L55M polymorphism (a leucine (L) to methionine (M) substitution at position 55), and ...
Oya Yigittürk   +4 more
doaj   +1 more source

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