Results 11 to 20 of about 6,713 (180)
Marked Long-Term Improvement in Lung Function in Melanoma Differentiation-Associated Protein 5 Antibody-Positive Dermatomyositis Patients: Experience of a Single-Center Longitudinal Cohort in North America. [PDF]
Arthritis Care Res (Hoboken)Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Cheah JX +8 more
europepmc +2 more sources
Viruses, 2022 Paraoxonase-1 (PON1), an esterase with specifically paraoxonase activity, has been proven to be involved in inflammation and infection. Porcine reproductive and respiratory syndrome virus (PRRSV) is still a major concern in pigs and causes severe ...
Lin Zhang +11 more
doaj +1 more source
Role of Paraoxonase-1 (Q192R) Gene Polymorphism in Coronary Artery Disease in Saudi Arabian Population [PDF]
JLUMHS, 2019 OBJECTIVES: To assess the prevalence and dissemination of PON1 Q192R polymorphism and PON1 activities in CAD patients and controls. METHODOLOGY: A case control study, conducted from October 2016 to December 2017.
Samir Abdulkarim Alharbi +2 more
doaj +1 more source
Antioxidants, 2020 High-density lipoprotein (HDL), in addition to promoting reverse cholesterol transport, possesses anti-inflammatory, antioxidative, and antithrombotic activities.
Marta Sikora +5 more
doaj +1 more source
Paraoxonase 1 gene polymorphisms in lipid oxidation and atherosclerosis development
Frontiers in Genetics, 2022 Paraoxonase 1 (PON1) is calcium-dependent aryldialkylphosphatase, thought to possess; anti-oxidant, anti-adhesion, anti-inflammatory, anti-thrombosis and anti-apoptosis effects, as well as lipid-modifying properties.
Marija Vavlukis +4 more
doaj +1 more source
Journal of Sport and Health Science, 2023 Background: Low levels of antioxidant paraoxonase 1 (PON1) enzyme activity, PON1–Q192R polymorphism (a glutamine (Q) to arginine (R) substitution at position 192), PON1–L55M polymorphism (a leucine (L) to methionine (M) substitution at position 55), and ...
Oya Yigittürk +4 more
doaj +1 more source
Effect of PON1 on dichlorvos toxicokinetics [PDF]
Emergency Medicine Journal, 2010 To provide toxicokinetic and clinical evidence of the hydrolytic effect of paraoxonase-1 (PON1) on acute organophosphate poisoning in rats.40 male Wistar rats were randomised into four equal groups. Dichlorvos administration group (A group) underwent dichlorvos injection (dissolved in corn oil) using intraperitoneal (ip) dose of 10 mg/kg.
Wang, Na-Na +4 more
openaire +2 more sources
Journal of Lipid Research, 2006 Paraoxonase 1 (PON1) activity is consistently predictive of vascular disease, although the genotype at four functional PON1 polymorphisms is not. To address this inconsistency, we investigated the role of all common PON1 genetic variability, as measured ...
Christopher S. Carlson +13 more
doaj +1 more source
Antioxidant status in hypertensive disorders of pregnancy
Hypertension in Pregnancy, 2022 Objective Pregnancy can be associated with maternal hypertension leading to possible complications in pregnancy outcome. Antioxidant status may be proned to changes during pregnancy with hypertension.
Jasmina Ivanišević +11 more
doaj +1 more source
Cells, 2023 Paraoxonase 1 (PON1), a homocysteine (Hcy)-thiolactone detoxifying enzyme, has been associated with Alzheimer’s disease (AD), suggesting that PON1 plays an important protective role in the brain.
Łukasz Witucki, Hieronim Jakubowski
doaj +1 more source