Results 21 to 30 of about 9,907 (172)
Abstract Breast cancer (BC) is most prevalent in females but also accounts for <1% of male cancer cases and 0.2% of male cancer‐related deaths. Distribution of histological subtypes, receptor status, and age of diagnosis varies based on sex, and a growing body of evidence supports sex‐specific molecular differences in BC.
Subarnarekha Chatterji +11 more
wiley +1 more source
The Neuroprotective Effect of a Waste Byproduct Obtained From Pomegranate (Punica granatum)
The Effect of a Waste Byproduct Obtained From Pomegranate on Neurodegeneration. ABSTRACT Pomegranate is an exceptional fruit that can have several beneficial effects on human health. The peel of pomegranate, a waste product, should be recovered as it still contains valuable constituents, including phenolic compounds, minerals and fibre. The recovery of
Jessica Maiuolo +11 more
wiley +1 more source
Blood‐based proteomic signature of amyloidosis: identification of novel regulators of amyloid load
Abstract INTRODUCTION Cerebral amyloidosis is a defining feature of Alzheimer's disease (AD), yet the molecular heterogeneity among amyloidbeta‐positive (Aβ+) individuals remains poorly defined. We aimed to map the proteomic correlates of cerebral amyloidosis and link them to clinical variability within Aβ+ individuals.
Yike Chen +18 more
wiley +1 more source
OP-hydrolyzing activity of the rh-PON1 enzymes.
(A) compares the Pxn-hydrolyzing activity of the recombinant enzymes. The Pxn-hydrolyzing activity was determined using direct assay. Equal amounts of the rh-PON1 enzymes were incubated with 1 mM paraoxon in the activity buffer (50 mM Tris-HCl, pH 8.0 ...
Priyanka Bajaj (1786471) +6 more
core +1 more source
Aerial (leaves and flowers) and belowground (bulbs and roots) parts of Galanthus elwesii were extracted using water, 70% ethanol, and 80% methanol. Phytochemical analyses revealed organ‐ and solvent‐dependent variations in total phenolic and flavonoid contents, which were associated with differences in in vitro antioxidant activity determined by DPPH ...
Osman Ertan, Arif Ayar, Ebru Batı Ay
wiley +1 more source
Levels of biochemical parameters of PON1 55 and PON1 192 carriers in the ACS patient group.
The unpaired student’s t-test was used.Levels of biochemical parameters of PON1 55 and PON1 192 carriers in the ACS patient group.
Pamela Camponova (779670) +11 more
core +1 more source
We performed longitudinal evaluation using magnetic resonance imaging (MRI) and dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) in a case of organophosphate‐induced toxic parkinsonism. Fluid‐attenuated inversion recovery (FLAIR) images showed bilateral striatal hyperintensity in the acute phase, followed by reduction of ...
Shuhei Nakao +6 more
wiley +1 more source
The PON1 Q192R genotype was determined by RT-PCR. PON1 paraoxonase activity was determined by measuring paraoxon absorbance at 412 nm.
Pamela Camponova (779670) +11 more
core +1 more source
Current bladder cancer therapies can cause toxicity and bladder dysfunction. Brief intravesical‐like aripiprazole exposure reduced bladder cancer cell viability and was associated with redox stress and caspase‐3 activation, while ex vivo findings suggested preserved bladder structure and function, warranting further investigation as a potential ...
Liam A. O'Callaghan +3 more
wiley +1 more source
Abstract Introduction Type 2 diabetes is a complex condition with a multifactorial pathogenesis. The pathogenesis is considered to be polygenic due to complex interactions between genetic/epigenetic and environmental factors. The aim of this study is to determine the genetic, environmental and lifestyle factors associated with the development of type 2
Sunny Chinenye +18 more
wiley +1 more source

