Results 21 to 30 of about 20,745 (266)

PON1 status does not influence cholinesterase activity in Egyptian agricultural workers exposed to chlorpyrifos. [PDF]

, 2012
Animal studies have shown that paraoxonase 1 (PON1) genotype can influence susceptibility to the organophosphorus pesticide chlorpyrifos (CPF). However, Monte Carlo analysis suggests that PON1 genotype may not affect CPF-related toxicity at low exposure ...
Bonner, Matthew R, Browne, Richard W, Crane, Alice L, Ellison, Corie A, Knaak, James B, Lein, Pamela J, Olson, James R   +6 more
core   +1 more source

TagSNP analyses of the PON gene cluster: effects on PON1 activity, LDL oxidative susceptibility, and vascular disease

Journal of Lipid Research, 2006
Paraoxonase 1 (PON1) activity is consistently predictive of vascular disease, although the genotype at four functional PON1 polymorphisms is not. To address this inconsistency, we investigated the role of all common PON1 genetic variability, as measured ...
Christopher S. Carlson, Patrick J. Heagerty, Thomas S. Hatsukami, Rebecca J. Richter, Jane Ranchalis, Julieann Lewis, Tamara J. Bacus, Laura A. McKinstry, Gerard D. Schellenberg, Mark Rieder, Deborah Nickerson, Clement E. Furlong, Alan Chait, Gail P. Jarvik   +13 more
doaj   +1 more source

Genetic Attenuation of Paraoxonase 1 Activity Induces Proatherogenic Changes in Plasma Proteomes of Mice and Humans

Antioxidants, 2020
High-density lipoprotein (HDL), in addition to promoting reverse cholesterol transport, possesses anti-inflammatory, antioxidative, and antithrombotic activities.
Marta Sikora, Ewa Bretes, Joanna Perła-Kaján, Izabela Lewandowska, Łukasz Marczak, Hieronim Jakubowski   +5 more
doaj   +1 more source

Antioxidant status in hypertensive disorders of pregnancy

Hypertension in Pregnancy, 2022
Objective Pregnancy can be associated with maternal hypertension leading to possible complications in pregnancy outcome. Antioxidant status may be proned to changes during pregnancy with hypertension.
Jasmina Ivanišević, Daniela Ardalić, Gorica Banjac, Jelena Janać, Petar Cabunac, Jelena Vekić, Aleksandra Zeljković, Vesna Spasojević- Kalimanovska, Nataša Karadžov Orlić, Vesna Mandić Marković, Željko Miković, Aleksandra Stefanović   +11 more
doaj   +1 more source

Serum biomarkers of oxidative stress in dogs with idiopathic inflammatory bowel disease [PDF]

, 2017
© 2017 Elsevier Ltd. This document is the published version of a published work that appeared in final form in Veterinary Journal. To access the final edited and published work see: https://doi.org/10.1016/j.tvjl.2017.02.003The objective of this ...
Allenspach, K, Cerón, J J, Hernández-Ruiz, J, Martínez-Subiela, S, Rubio, C P, Tvarijonaviciute, A   +5 more
core   +2 more sources

The Increase in Paraoxonase 1 Is Associated With Decrease in Left Ventricular Volume in Kidney Transplant Recipients

Frontiers in Cardiovascular Medicine, 2021
Background: Patients on dialysis have impaired cardiac function, in part due to increased fluid volume and ventricular stress. Restored kidney function through transplantation reduces left ventricular volume in both systole and diastole.
Philip W. Connelly, Philip W. Connelly, Philip W. Connelly, Andrew T. Yan, Michelle M. Nash, Rachel M. Wald, Charmaine Lok, Lakshman Gunaratnam, Anish Kirpalani, G. V. Ramesh Prasad   +9 more
doaj   +1 more source

Extended-release niacin increases anti-apolipoprotein A-I antibodies that block the antioxidant effect of high-density lipoprotein-cholesterol: the EXPLORE clinical trial. [PDF]

, 2017
Extended-release niacin (ERN) is the most effective agent for increasing high-density lipoprotein-cholesterol (HDL-C). Having previously identified anti-HDL antibodies, we investigated whether ERN affected the antioxidant capacity of HDL and whether ERN ...
Alves, JD, Amaral, M, Ames, P, Batuca, J, Favas, C, Papoila, A, Paula, F   +6 more
core   +1 more source

Lactonase Activity, Status, and Genetic Variations of Paraoxonase 1 in Women with Gestational Diabetes Mellitus

Journal of Diabetes Research, 2020
Background. Paraoxonase 1 (PON1) is a calcium-dependent multifunctional enzyme that binds to high-density lipoproteins. The physiological function of PON1 is related to its lactonase activity.
Mi Zhou, Xing-Hui Liu, Qing-Qing Liu, Meng Chen, Huai Bai, Lin-Bo Guan, Ping Fan   +6 more
doaj   +1 more source

Oral chondroitin sulfate and prebiotics for the treatment of canine Inflammatory Bowel Disease: a randomized, controlled clinical trial [PDF]

, 2016
BACKGROUND Canine inflammatory bowel disease (IBD) is a chronic enteropathy of unknown etiology, although microbiome dysbiosis, genetic susceptibility, and dietary and/or environmental factors are hypothesized to be involved in its pathogenesis. Since
A Ghiselli, A Tvarijonaviciute, A Wächtershäuser, ABC Samuelsen, AE Jergens, AE Jergens, AJ Schottelius, Alberto Muñoz-Prieto, Alfonso Velasco, Antonio Rodríguez-Bertos, CG Fraga, CS Brennan, D Boehm, D Martínez-Puig, Daniel Martínez-Puig, E Gisbert, Fernando Rodríguez-Franco, G Rossi, G Rossi, IE Koutroubakis, JE Fogle, JJ Ceron, José Cerón, JS Suchodolski, JS Suchodolski, K Allenspach, K Allenspach, Karin Allenspach, KS Swanson, KW Simpson, L Kaufman, M Castillo, M García-Sancho, M Krzystek-Korpacka, M Nofrarías, M Roca, M Volkmann, MA Murphy, Marta Cerdà-Cuéllar, MT Collins, N Luckschander, O Erel, P Souich du, PG Xenoulis, RJ Washabau, S Martinez-Subiela, Sergi Segarra, Silvia Martínez-Subiela, TM McCann, VL Cabral, Y Minamoto, Y You   +51 more
core   +6 more sources

Resveratrol exhibits an effect on attenuating retina inflammatory condition and damage of diabetic retinopathy via PON1

Experimental Eye Research, 2019
Diabetic retinopathy (DR), an obstacle of the visual microvascular system, is a serious complication of diabetic patients. Paraoxonase 1 (PON1) has been extensively evaluated as a genetic candidate for diabetic microvascular complications, and PON1 is ...
Yuhua Chen, Jiao Meng, Hua Li, Hong Wei, Fangfang Bi, Shi Liu, K. Tang, Haiyu Guo, Wei Liu   +8 more
semanticscholar   +1 more source