Results 41 to 50 of about 22,824 (262)

Paraoxonase 1 Activity and its Polymorphism in Type 2 Diabetic Nephropathy

Endocrinology Research and Practice, 2018
Objective: This study aims to investigate the role of paraoxonase 1 activity and Q192R polymorphism in the development of nephropathy in patients with Type 2 diabetes mellitus.
Mukund R. MOGAREKAR, Mahendrakumar G. DHABE, Mayuri M. PALMATE   +2 more
doaj   +1 more source

Pioglitazone activates paraoxonase-2 in the brain: a novel neuroprotective mechanism

Experimental Neurology, 2020
Paraoxonase-2 regulates reactive oxygen species production in mitochondria. Stimulating its expression has therapeutic potential for diseases where oxidative stress plays a significant role in the pathology.
Jennifer K. Blackburn, D. Curry, Anna N Thomsen, R. Roth, J. Elsworth   +4 more
semanticscholar   +1 more source

Lower paraoxonase 1 activity in Tunisian bipolar I patients

Annals of General Psychiatry, 2010
Background The purpose of this study was to investigate the variations of paraoxonase activity and lipid profile in bipolar I patients, and the association of this activity with the sociodemographic, clinical and therapeutic characteristics of this ...
Araoud Manel, Mechri Anwar, Mouhamed Dhouha, Ezzaher Asma, Neffati Fadoua, Douki Wahiba, Gaha Lotfi, Najjar Mohamed   +7 more
doaj   +1 more source

Serum paraoxonase levels of schizophrenia patients treated with typical, atypical and combined antipsychotics

Psychiatry and Clinical Psychopharmacology, 2021
Objective: Schizophrenia is a devastating disorder, starting in early adulthood and continuing with relapses and remissions. Prevalence of schizophrenia is 1% and the life expectancy of these patients is reduced.
Mehmet Akif Camkurt, Mehmet Gunes, Süleyman Demir, Aslihan İbiloglu, Mehmet Cemal Kaya, Mahmut Bulut, Abdullah Atli   +6 more
doaj  

Effect of Exercise Repetitions on Arylesterase Activity of PON1 in Plasma of Average-Trained Men—The Dissociation between Activity and Concentration

Antioxidants, 2023
Exercise may increase the antioxidant capacity of plasma by stimulating antioxidant enzymes. The study aimed to measure the effect of three repetitions of acute exercise on arylesterase (ARE) activity of the paraoxonase 1 (PON1) enzyme.
Aneta Otocka-Kmiecik, Monika Orłowska-Majdak, Robert Stawski, Urszula Szkudlarek, Gianluca Padula, Szymon Gałczyński, Dariusz Nowak   +6 more
doaj   +1 more source

Homocysteinethiolactone and Paraoxonase [PDF]

Diabetes Care, 2010
OBJECTIVE Paraoxonase (PON) exhibits esterase activity (PON-AREase) and lactonase activity (PON-HCTLase), which prevent LDL oxidation and detoxify homocysteine thiolactone (HCTL). The role of HCTL and PON-HCTLase as a risk factor for the microvascular complication in diabetic retinopathy at the level of vitreous has
Subramaniam Barathi, Narayanasamy Angayarkanni, Aarthi Pasupathi, Sulochana Konerirajapuram Natarajan, Rishi Pukraj, Maneesh Dhupper, Thirumurthy Velpandian, Charanya Muralidharan, Muthukumaran Sivashanmugham   +8 more
openaire   +1 more source

Low Serum Paraoxonase-1 Lactonase and Arylesterase Activities in Obese Children and Adolescents

Romanian Journal of Laboratory Medicine, 2015
Serum paraoxonase-1 (PON1) binds mainly to high density lipoproteins (HDLs) and protects low density lipoproteins (LDLs) against oxidation. While paraoxonase and arylesterase activities are traditionally assayed, lactonase activity, accounting for ...
Sandor Raluca, Leucuta Daniel, Dronca Eleonora, Niculae Alexandru, Cret Victoria, Silaghi Ciprian, Suciu Soimita   +6 more
doaj   +1 more source

The effect of homocysteine thiolactone on paraoxonase and aryl esterase activity of human serum purified paraoxonase 1 in vitro experiments [PDF]

, 2022
BACKGROUND: The important role of lipoproteins, particularly low-density lipoprotein (LDL) and high-density lipoprotein (HDL), has been highly regarded among the known causes of cardiovascular disease (CVD).
Moshtaghie, A. A., Nayeri, H., Moshtaghie, E., Asgary, S.   +3 more
core   +1 more source

Serum Oxidative Stress Levels in Patients with Nasal Septal Deviation

Turkish Archives of Otorhinolaryngology, 2017
Objective:Comparison of the total oxidant status (TOS), total antioxidant status (TAS) and paraoxonase (PON1) serum levels in patients with nasal septum deviation (NSD) and healthy subjects.Methods:The TAS, TOS, and PON1 serum levels of 47 patients with ...
Adnan Ekinci, Duran Karataş, Abdurrahman Yetiş, Emre Demir, Müge Özcan   +4 more
doaj   +1 more source

Elevation of plasma phospholipid transfer protein increases the risk of atherosclerosis despite lower apolipoprotein B-containing lipoproteins

Journal of Lipid Research, 2004
Plasma phospholipid transfer protein (PLTP) transfers phospholipids between lipoproteins and mediates HDL conversion. PLTP-overexpressing mice have increased atherosclerosis.
Jessica Lie, Rini de Crom, Teus van Gent, Rien van Haperen, Leo Scheek, Farah Sadeghi-Niaraki, Arie van Tol   +6 more
doaj   +1 more source