Results 61 to 70 of about 22,824 (262)

Alterações no metabolismo lipídico em pacientes HIV soropositivos [PDF]

, 2007
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em FarmáciaO HIV infecta e depleta os linfócitos T CD4, resultando em imunodeficiência e progressão da doença. Os pacientes infectados
Daminelli, Elaine Nunes
core  

Antioxidant properties of HDL

Frontiers in Pharmacology, 2015
High-density lipoprotein (HDL) provides a pathway for the passage of lipid peroxides and lysophospholipids to the liver via hepatic scavenger receptors. Perhaps more importantly, HDL actually metabolises lipid hydroperoxides preventing their accumulation
Handrean eSoran, Handrean eSoran, Jonathan David Schofield, Jonathan David Schofield, Paul N Durrington   +4 more
doaj   +1 more source

Why Should Psychiatrists and Neuroscientists Worry about Paraoxonase 1?

Current Neuropharmacology, 2019
Background: Nitro-oxidative stress (NOS) has been implicated in the pathophysiology of psychiatric disorders. The activity of the polymorphic antioxidant enzyme paraoxonase 1 (PON1) is altered in diseases where NOS is involved.
E. Moreira, Karine Maria Boll, D. Correia, Janaína Favaro Soares, C. Rigobello, M. Maes   +5 more
semanticscholar   +1 more source

Chronic, Environmentally Relevant PM2.5 Exposure Exacerbates Metabolic Dysfunction‐Associated Steatotic Liver Disease and Early‐Stage Renal Dysfunction in a Rodent Model

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT While epidemiological studies link fine particulate matter (PM2.5) exposure to metabolic dysfunction‐associated steatotic liver disease (MASLD) and renal dysfunction, a translational gap exists, as most animal models utilize acute, high‐dose exposures that poorly reflect chronic, moderate‐level human scenarios.
Yi‐Siao Chen, Hugo You‐Hsien Lin, Chien‐Tzu Lin, Si‐Hua Huang, Ming‐Lun Yeh, Ming‐Lung Yu, Jin‐Ching Lee, Yao‐Chi Chung, Wei‐Ming Li, Ching‐Chia Li, Shiu‐Feng Huang, Chia‐Hung Yen   +11 more
wiley   +1 more source

Efeito da erva-mate (Ilex paraguariensis, St. Hill.) na modulação gênica e na atividade da enzima paroxonase: estudos in vitro e in vivo [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-graduação em Nutrição, Florianópolis, 2011A erva-mate (Ilex paraguariensis) espécie vegetal usada no preparo de bebidas como o chimarrão, o ...
Fernandes, Elenise Stuker
core  

Sepsis in Dogs and Cats—Consensus Definition and Clinical Criteria

Journal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Sepsis is the clinical syndrome that results from the host response to severe or widespread infection and is a frequent cause of death in veterinary critical care settings. Rapid diagnosis aids early treatment initiation, and hence, how sepsis is defined and identified clinically has implications for patient outcomes.
Robert Goggs, Stefano Cortellini, Amy E. DeClue, Massimo Giunti, Kate Hopper, Julie M. Menard, Rodrigo C. Rabelo, Elizabeth A. Rozanski, Claire R. Sharp, Deborah C. Silverstein, Virginia Sinnott‐Stutzman, Giacomo Stanzani, John Bourgeois, Erik Fausak   +13 more
wiley   +1 more source

Paraoxonase 1 polymorphisms and survival [PDF]

European Journal of Human Genetics, 2004
The antioxidant enzyme paraoxonase 1 (PON1) has previously been suggested to confer protection against coronary heart disease (CHD), one of the main causes of death in the Western world. Two coding polymorphisms, 55M/L and 192Q/R, and a promoter variant, -107C/T, has been extensively studied with respect to susceptibility to CHD. In this study, we have
Christiansen, Lene, Bathum, Lise, Frederiksen, Henrik, Christensen, Kaare   +3 more
openaire   +2 more sources

Paraoxonase 3: Structure and Its Role in Pathophysiology of Coronary Artery Disease

Biomolecules, 2019
Spanning three decades in research, Paraoxonases (PON1) carried potential of dealing with neurotoxicity of organophosphates entering the circulation and preventing cholinergic crisis.
K. Priyanka, Surjit Singh, K. Gill
semanticscholar   +1 more source

Environmental Pesticide Exposure in the Etiology of Pediatric Brain Tumors and Leukemia: A Scoping Review of Epidemiological Studies

International Journal of Cancer, Volume 159, Issue 6, Page 1360-1384, 15 September 2026.
ABSTRACT Pediatric cancer is a significant cause of morbidity and mortality in children. The etiologies of pediatric cancer are largely unknown, but environmental pesticide exposures are likely to contribute. Chronic low‐dose exposure to pesticide mixtures through drinking water is a growing concern in agricultural communities.
Grace N. VanDeSteeg, Alyssa R. Russum, Matthew R. Sandbulte, Eleanor G. Rogan, Martha G. Rhoades   +4 more
wiley   +1 more source

The paraoxonase 1, paraoxonase 2 and paraoxonase 3 in humans

Biochemia medica, 2011
The paraoxonase gene family in humans includes three members: pon1, pon2 and pon3. The products of those three genes are the following enzymes: paraoxonase 1 (PON1), paraoxonase 2 (PON2) and paraoxonase 3 (PON3). PON1 is mainly associated with a high density lipoprotein (HDL). A small amount of this enzyme is also bound to very low-density lipoprotein (
Rumora, Lada, Barišić, Karmela, Grdić Rajković, Marija   +2 more
openaire   +1 more source