Results 51 to 60 of about 23,747 (229)
Psychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.We performed longitudinal evaluation using magnetic resonance imaging (MRI) and dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) in a case of organophosphate‐induced toxic parkinsonism. Fluid‐attenuated inversion recovery (FLAIR) images showed bilateral striatal hyperintensity in the acute phase, followed by reduction of ...
Shuhei Nakao +6 more
wiley +1 more source
Paraoxonase 1 and Non-Alcoholic Fatty Liver Disease: A Meta-Analysis
Molecules, 2021 Oxidative stress is involved in the pathophysiology of nonalcoholic fatty liver disease (NAFLD). However, reliable biomarkers of NAFLD in relation to oxidative stress are not available.
Kazuhiko Kotani +3 more
doaj +1 more source
Protein glycosylation in lung cancer from a mass spectrometry perspective
Mass Spectrometry Reviews, Volume 45, Issue 3, Page 455-475, May/June 2026.ABSTRACT Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi +2 more
wiley +1 more source
Antioxidants, 2023 Although AMD is a complex disease, oxidative stress is a crucial contributor to its development, especially in view of the higher oxygen demand of the retina. Paraoxonase 2 (PON2) is a ubiquitously and constitutively expressed antioxidant protein that is
Parameswaran Gangadharan Sreekumar +8 more
doaj +1 more source
Paraoxonase (PON1 and PON3) Polymorphisms: Impact on Liver Expression and Atorvastatin-Lactone Hydrolysis [PDF]
, 2011 Atorvastatin δ-lactone, a major, pharmacologically inactive metabolite, has been associated with toxicity. In a previous study we showed that polymorphisms of UGT1A3 influence atorvastatin δ-lactone formation.
Stephan eRiedmaier +7 more
core +2 more sources
Aging Cell, Volume 25, Issue 5, May 2026.We revealed the pathophysiological significance and therapeutic potential of adipocyte mitochondrial NAD transporter, namely solute carrier family 25 member 51 (SLC25A51), in age‐associated metabolic diseases, particularly adipose tissue mitochondrial function, obesity, and insulin resistance, by analyzing adipocyte‐specific Slc25a51 knockout (ASKO ...
Daiki Kojima +19 more
wiley +1 more source
Paraoxonases Activities and Polymorphisms in Elderly and Old-Age Diseases: An Overview
Antioxidants, 2019 Aging is defined as the accumulation of progressive organ dysfunction. There is much evidence linking the involvement of oxidative stress in the pathogenesis of aging.
Débora Levy +2 more
doaj +1 more source
Advanced Science, Volume 13, Issue 22, 17 April 2026.In this study, a highly robust N‐glycoproteomics (HRN) platform with a newly developed match‐between‐run scheme is used for biomarker discovery. This study proposes a protein‐centric strategy to prioritize proteins susceptible to aberrant glycosylation.
Lei Liu +15 more
wiley +1 more source
Effect of Andrographolide on Paraoxonase 2 Expression in Male Wistar Rats
Journal of Mazandaran University of Medical Sciences, 2018 Background and purpose: The paraoxonase 2 is one of the paraoxonase family enzymes, which, unlike the paraoxonase 1 and 3, is an intracellular antioxidant system expressed in many cells. Andrographophyllide is a plant that has recently received attention
Reza Alipanah Moghadam +8 more
doaj
The relationship between serum ferritin levels and serum lipids and HDL function with respect to age and gender [PDF]
The Ukrainian Biochemical Journal, 2016 Elevated serum ferritin (SFer) levels have been associated with chronic diseases such as coronary heart disease and diabetes mellitus type 2. The aim of this study was to examine the relationship between SFer levels and serum lipid parameters, and how ...
Hamit Yasar Ellidag +5 more
doaj +1 more source