Results 51 to 60 of about 16,692 (213)
Antioxidants, 2023 Although AMD is a complex disease, oxidative stress is a crucial contributor to its development, especially in view of the higher oxygen demand of the retina. Paraoxonase 2 (PON2) is a ubiquitously and constitutively expressed antioxidant protein that is
Parameswaran Gangadharan Sreekumar +8 more
doaj +1 more source
Seminal Extracellular Vesicles as Molecular Modulators of Male Reproductive Function
Reproduction in Domestic Animals, Volume 61, Issue S3, October 2026.ABSTRACT Extracellular vesicles (sEVs) contained in seminal plasma (SP) maintain, in concert with free SP‐components (proteins, hormones, cytokines, metabolites and antioxidants) under an endocrine umbrella the functional in vivo homeostasis of ejaculated spermatozoa. The sEVs define a generic mixture of nanovesicles delivered by male epithelial cells,
Heriberto Rodriguez‐Martinez +3 more
wiley +1 more source
The paraoxonase 1, paraoxonase 2 and paraoxonase 3 in humans
Biochemia medica, 2011 The paraoxonase gene family in humans includes three members: pon1, pon2 and pon3. The products of those three genes are the following enzymes: paraoxonase 1 (PON1), paraoxonase 2 (PON2) and paraoxonase 3 (PON3). PON1 is mainly associated with a high density lipoprotein (HDL). A small amount of this enzyme is also bound to very low-density lipoprotein (
Rumora, Lada +2 more
openaire +1 more source
Effect of Andrographolide on Paraoxonase 2 Expression in Male Wistar Rats
Journal of Mazandaran University of Medical Sciences, 2018 Background and purpose: The paraoxonase 2 is one of the paraoxonase family enzymes, which, unlike the paraoxonase 1 and 3, is an intracellular antioxidant system expressed in many cells. Andrographophyllide is a plant that has recently received attention
Reza Alipanah Moghadam +8 more
doaj
International Journal of Cancer, Volume 159, Issue 6, Page 1360-1384, 15 September 2026.ABSTRACT Pediatric cancer is a significant cause of morbidity and mortality in children. The etiologies of pediatric cancer are largely unknown, but environmental pesticide exposures are likely to contribute. Chronic low‐dose exposure to pesticide mixtures through drinking water is a growing concern in agricultural communities.
Grace N. VanDeSteeg +4 more
wiley +1 more source
European Journal of Breast HealthObjective: Among women, breast cancer (BC) is the most prevalent form of cancer. Many molecular targets have been discovered for BC prognosis and treatment.
Durmuş Ayan +3 more
doaj +1 more source
The relationship between serum ferritin levels and serum lipids and HDL function with respect to age and gender [PDF]
The Ukrainian Biochemical Journal, 2016 Elevated serum ferritin (SFer) levels have been associated with chronic diseases such as coronary heart disease and diabetes mellitus type 2. The aim of this study was to examine the relationship between SFer levels and serum lipid parameters, and how ...
Hamit Yasar Ellidag +5 more
doaj +1 more source
Paraoxonases at the Heart of Neurological Disorders
International Journal of Molecular Sciences, 2023 Paraoxonase enzymes serve as an important physiological redox system that participates in the protection against cellular injury caused by oxidative stress. The PON enzymes family consists of three members (PON-1, PON-2, and PON-3) that share a similar structure and location as a cluster on human chromosome 7.
Fatimah K. Khalaf +11 more
openaire +2 more sources
Paraoxonase and Arylesterase Activities in Patients with Preeclampsia
Eurasian Journal of Medicine, 2019 Objective: Paraoxonase is a high density lipoprotein-associated antioxidant enzyme. The aim of this study was to investigate the serum paraoxonase and arylesterase activities and associations between these enzymes and lipid hydroperoxide (LOOH) in ...
Ayse Nur Aksoy +3 more
doaj
Cardiovascular disease incidence and cancer risk in two large European prospective cohorts
International Journal of Cancer, Volume 159, Issue 5, Page 1139-1152, 1 September 2026.What's new? Cardiovascular disease (CVD) and cancer share risk factors and biological mechanisms, raising questions about potential associations between the two, particularly regarding CVD duration and cancer onset. Whether CVD influences subsequent cancer risk, however, remains inconclusive.
Emma Fontvieille +25 more
wiley +1 more source