Reevaluation of Serum Arylesterase Activity in Neurodevelopmental Disorders [PDF]
Antioxidants, 2021 Organophosphate compounds (OPs) interfere with neurodevelopment and are neurotoxic for humans and animals. They are first biotransformed to the more toxic oxon form, and then hydrolyzed to specific metabolites by the enzyme paraoxonase/arylesterase ...
Ignazio Stefano Piras +11 more
doaj +6 more sources
Antioxidants, 2020 Background: It has been suggested that circulating Paraoxonase-1 (PON1) and apolipoprotein A1 (APOA1), which closely interacts with the antioxidant enzyme, could be implicated in Alzheimer’s disease (AD) and vascular dementia (VaD) development.
Arianna Romani +6 more
doaj +4 more sources
Lipids in Health and Disease, 2021 Background Recent studies focused on modulating factors of paraoxonase-1 (PON1) activity. In some studies the association between pro-inflammatory markers and PON1 activity was examined, but so far no population-based investigations on this issue have ...
Christa Meisinger +3 more
doaj +2 more sources
Paraoxonase/Arylesterase Activity of Serum Paraoxonase-1 and Schizophrenia: A Systematic Review and Meta-Analysis [PDF]
Antioxidants, 2023 The presence of a pro-oxidant state in patients with schizophrenia may account for the increased risk of atherosclerosis and cardiovascular disease in this group and supports the potential utility of circulating biomarkers of oxidative stress for risk ...
Angelo Zinellu +2 more
doaj +2 more sources
Total oxidative stress, paraoxonase and arylesterase levels at patients with pseudoexfoliation syndrome and pseudoexfoliative glaucoma [PDF]
International Journal of Ophthalmology, 2015 AIM:To investigate the oxidative stress status of the aqueous humor and serum of patients with pseudoexfoliation (PEX) syndrome and pseudoexfoliative glaucoma (PEG) and to measure paraoxonase (PON) and arylesterase (ARE) levels.METHODS: A total of 78 ...
Feyza Dursun +7 more
doaj +2 more sources
Evaluation of serum paraoxonase and arylesterase activities in ankylosing spondylitis patients
Clinics, 2010 OBJECTIVES: The aim of this study was to investigate the activities of serum paraoxonase and arylesterase in patients with ankylosing spondylitis with respect to those of healthy controls, to assess whether these enzyme levels are related to disease ...
Fazile Hatipoglu Erdem +3 more
doaj +3 more sources
Associations of PON1 and genetic ancestry with obesity in early childhood. [PDF]
, 2013 Obesity in children has become an epidemic in the U.S. and is particularly prominent in minority populations such as Mexican-Americans. In addition to physical activity and diet, genetics also plays a role in obesity etiology. A few studies in adults and
Beckman, Kenneth +4 more
core +9 more sources
Antioxidants, 2023 Exercise may increase the antioxidant capacity of plasma by stimulating antioxidant enzymes. The study aimed to measure the effect of three repetitions of acute exercise on arylesterase (ARE) activity of the paraoxonase 1 (PON1) enzyme.
Aneta Otocka-Kmiecik +6 more
doaj +1 more source
High-density lipopoprotein antioxidant capacity, subpopulation distribution and paraoxonase-1 activity in patients with systemic lupus erythematosus [PDF]
, 2016 BACKGROUND: The causes of increased cardiovascular risk in systemic lupus erythematosus (SLE) are not understood thoroughly, although presence of traditional cardiovascular risk factors and disease-specific agents were also proposed.
György Paragh +7 more
core +4 more sources
Expression of paraoxonase 1 in HEK293 cells and its effect on lactonase and arylesterase activity in samples containing human serum and/or prooxidant or antioxidant agents - a preliminary study [PDF]
Acta Poloniae Pharmaceutica, 2023 Expression of recombinant paraoxonase 1 (PON1) in the human embryonic kidney (HEK293F) cell line was evaluated. Two recombinant human PON1 proteins were investigated: PON1-Fc, which has an Fc-tag on its C-terminal, and His-PON1-Fc, which has an Fc-tag on
Anna Bizoń, Agnieszka Piwowar
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