Separation and quantitative recovery of mouse serum arylesterase and carboxylesterase activity
Paraoxonase-1 (PON1) is known to be associated with high density lipoproteins. We optimized buffer conditions to obtain quantitative recovery of PON1 (arylesterase) activity and analyzed the distribution of PON1 in mice using a combination of size ...
Philip W. Connelly +2 more
doaj +1 more source
Extraction and characterization of Arylesterase enzyme from (peel and pulp) of Annona muricata fruit. [PDF]
The extraction of arylesterase from the aqueous extract of (peel and pulp) of Annona muricata fruit was conducted using different biochemical techniques.
Firdaws A. Almashhdani +2 more
doaj +1 more source
Noncatalytic Functions Are Required for MPO and PON1 in Modulating the Involvement of Monocytes and Endothelial Cells in Atherosclerosis. [PDF]
High‐density lipoproteins (HDLs) are deeply implicated in atherosclerosis. HDL, myeloperoxidase (MPO), and paraoxonase‐1 (PON1) form a functional ternary complex where PON1 partially inhibits the MPO activity, and MPO in turn partially inactivates PON1.
Li Y, Liu Y, Cheng Y.
europepmc +2 more sources
Paraoxonase and arylesterase activity in bladder cancer [PDF]
Abstract Objective: Oxidative stress is the main pathogenetic mechanism in bladder cancer among many other causes. We aimed to investigate whether a potential relationship exists between bladder cancer and the activities of paraoxonase (PON1) and arylesterase (ARE) enzymes.
Utangac, Mehmet Mazhar +6 more
openaire +3 more sources
Relationship of Serum Paraoxonase Enzyme Activity and Thermal Burn Injury
Objective: This study investigated changes in serum oxidative stress parameters in burn cases compared to healthy controls. Materials and Methods: This study was performed in 41 burn patients with mild to severe thermal burn injuries and 38 healthy ...
Serap Yildirim +5 more
doaj +1 more source
Oxidative stress and peri-implantitis: The role of oxidants and antioxidants [PDF]
Background: Peri-implantitis is the main cause of implant failure and is associated with augmented oxidative stress or tissue destruction. In this study, it was aimed to investigate the oxidant-antioxidant balance parameters in individuals with peri ...
Gülbahar Ustaoğlu +2 more
doaj +1 more source
Functional, Structural and Genetic Modulation in Plasma and Renal Antioxidant Systems by Quercetin, Catechin and Genistein in Cisplatin-Induced Acute Nephrotoxicity in Wistar Rats. [PDF]
Cisplatin administration increases production of reactive oxygen species (ROS) as indicated by increased plasma renal biomarkers (KIM‐1, Cys‐C, BUN, CR), cellular damage indicators (MDA, AOPP, 8‐OHdG) and histopathology of kidney. Co‐exposure along with quercetin, catechin and genistein restored the renal functions which may be due to direct ROS ...
Verma PK +8 more
europepmc +2 more sources
Distribution of Paraoxonase 1 polymorphisms and activities in obese patients
Obiectivul studiului a fost de investigarea fenotipului şi genotipului PON1 la pacienţii români cu obezitate abdominală. Material şi metodă. Loturile din studiu au constat din 88 de pacienţi cu obezitate abdominală şi 46 subiecţi cu circumferinţă ...
Ciumărnean Lorena +6 more
doaj +1 more source
Paraoxonase 1 Activity and its Polymorphism in Type 2 Diabetic Nephropathy
Objective: This study aims to investigate the role of paraoxonase 1 activity and Q192R polymorphism in the development of nephropathy in patients with Type 2 diabetes mellitus.
Mukund R. MOGAREKAR +2 more
doaj +1 more source
Paraoxonase 1 (PON1) is a serum enzyme associated with high density lipoprotein (HDL) regulation through its paraoxonase and arylesterase activity. PON1 inhibits the oxidation of HDL and low density lipoprotein (LDL), and is involved in the pathogenesis ...
Muhammad Idrees +7 more
doaj +1 more source

