Low Serum Paraoxonase-1 Lactonase and Arylesterase Activities in Obese Children and Adolescents [PDF]
Serum paraoxonase-1 (PON1) binds mainly to high density lipoproteins (HDLs) and protects low density lipoproteins (LDLs) against oxidation. While paraoxonase and arylesterase activities are traditionally assayed, lactonase activity, accounting for ...
Sandor Raluca +6 more
doaj +2 more sources
Arylesterase activity of paraoxonase 1 and intensity of oxidative processes in the blood of dialysis patients [PDF]
This study aimed to investigate the arylesterase activity of paraoxonase 1 (PON-1) in patients with end-stage renal disease (ESRD) and its relationship with oxidative stress markers. Methods.
L. Korol +2 more
doaj +3 more sources
Serum Paraoxonase, Arylesterase, and Glutathione-S-Transferase Activities and Oxidative Stress Levels in Patients with Mushroom Poisoning [PDF]
OBJECTIVES: Consumption of toxic species of mushrooms may have detrimental effects and increase oxidative stress. Paraoxonase, arylesterase and glutathione-S-transferase are antioxidants that resist oxidative stress.
Sevki Hakan Eren +4 more
doaj +2 more sources
Gut Bacterium Lysinibacillus Sphaericus Exacerbates Aspirin-induced Intestinal Injury by Production of Carboxylesterase EstB. [PDF]
Schematic overview illustrating the detrimental role of gut microbiota in aspirin‐induced intestinal injury. L. sphaericus and its secreted carboxylesterase EstB are identified as key drivers that catalyze aspirin hydrolysis into salicylic acid, thereby exacerbating intestinal injury. Inhibition of EstB by the dietary compound flavanomarein effectively
Zhao Z +13 more
europepmc +2 more sources
Oestrogen receptor phosphorylation profiles and in silico PAM50 subtyping reflect sexual dimorphism in breast cancer. [PDF]
Abstract Breast cancer (BC) is most prevalent in females but also accounts for <1% of male cancer cases and 0.2% of male cancer‐related deaths. Distribution of histological subtypes, receptor status, and age of diagnosis varies based on sex, and a growing body of evidence supports sex‐specific molecular differences in BC.
Chatterji S +11 more
europepmc +2 more sources
Noncatalytic Functions Are Required for MPO and PON1 in Modulating the Involvement of Monocytes and Endothelial Cells in Atherosclerosis. [PDF]
High‐density lipoproteins (HDLs) are deeply implicated in atherosclerosis. HDL, myeloperoxidase (MPO), and paraoxonase‐1 (PON1) form a functional ternary complex where PON1 partially inhibits the MPO activity, and MPO in turn partially inactivates PON1.
Li Y, Liu Y, Cheng Y.
europepmc +2 more sources
Paraoxonase-1 (PON-1) Arylesterase Activity Levels in Patients with Coronary Artery Disease: A Meta-Analysis [PDF]
Aim: To review and compare the PON-1 arylesterase activity between coronary artery disease (CAD) and non-CAD patients. Methods: Data were obtained by searching MEDLINE and Scopus for all investigations published between January 1, 2000 and March 1, 2021 ...
Zuin M. +9 more
core +1 more source
Functional, Structural and Genetic Modulation in Plasma and Renal Antioxidant Systems by Quercetin, Catechin and Genistein in Cisplatin-Induced Acute Nephrotoxicity in Wistar Rats. [PDF]
Cisplatin administration increases production of reactive oxygen species (ROS) as indicated by increased plasma renal biomarkers (KIM‐1, Cys‐C, BUN, CR), cellular damage indicators (MDA, AOPP, 8‐OHdG) and histopathology of kidney. Co‐exposure along with quercetin, catechin and genistein restored the renal functions which may be due to direct ROS ...
Verma PK +8 more
europepmc +2 more sources
Separation and quantitative recovery of mouse serum arylesterase and carboxylesterase activity
Paraoxonase-1 (PON1) is known to be associated with high density lipoproteins. We optimized buffer conditions to obtain quantitative recovery of PON1 (arylesterase) activity and analyzed the distribution of PON1 in mice using a combination of size ...
Philip W. Connelly +2 more
doaj +1 more source
Arylesterase activity in trace element contaminated soils [PDF]
Arylesterase activity was measured along with microbial biomass C (BC) and respiration, and H2O-soluble and NH4NO3-exchangeable trace elements (TE), in contaminated soils (TECS) from three long-term field trials.
Mench M. +14 more
core +1 more source

