Results 21 to 30 of about 7,599 (254)
Background: A decrease in serum paraoxonase (PON-1) and arylesterase (ARE) activity has been reported in rheumatoid arthritis (RA) patients and linked to chronic inflammation and impaired antioxidant defense.
G. Erre +6 more
semanticscholar +1 more source
The development of inexpensive, fast, and reliable screening tests for COVID-19 is, as yet, an unmet need. The present study was aimed at evaluating the usefulness of serum arylesterase activity of paraoxonase-1 (PON1) measurement as a screening test in ...
X. Gabaldó +17 more
semanticscholar +1 more source
Functional, Structural and Genetic Modulation in Plasma and Renal Antioxidant Systems by Quercetin, Catechin and Genistein in Cisplatin-Induced Acute Nephrotoxicity in Wistar Rats. [PDF]
Cisplatin administration increases production of reactive oxygen species (ROS) as indicated by increased plasma renal biomarkers (KIM‐1, Cys‐C, BUN, CR), cellular damage indicators (MDA, AOPP, 8‐OHdG) and histopathology of kidney. Co‐exposure along with quercetin, catechin and genistein restored the renal functions which may be due to direct ROS ...
Verma PK +8 more
europepmc +2 more sources
Endothelial Lipase Modulates Paraoxonase 1 Content and Arylesterase Activity of HDL
Endothelial lipase (EL) is a strong modulator of the high-density lipoprotein (HDL) structure, composition, and function. Here, we examined the impact of EL on HDL paraoxonase 1 (PON1) content and arylesterase (AE) activity in vitro and in vivo.
I. Schilcher +16 more
semanticscholar +1 more source
Background Controversy exists regarding the role of the subfractions of high-density lipoproteins (HDL2 and HDL3) in cardiovascular disease. The functionality of these particles, and their protective role, is due in part to the paraoxonase 1 (PON1 ...
Sandra Y. Valencia C +5 more
semanticscholar +1 more source
Background: Decreased concentration of both oestrogen hormone and vitamin D in postmenopausal period may lead to oxidative stress, lipid peroxidation, dyslipidaemia, osteoporosis, and cardiovascular diseases.
Behic Selman Erdogdu +3 more
doaj +1 more source
Paraoxonase 1 and Chronic Obstructive Pulmonary Disease: A Meta-Analysis
Oxidative stress is a driving factor in the pathophysiology of chronic obstructive pulmonary disease (COPD). While paraoxonase 1 (PON1) is an antioxidant enzyme and a potential biomarker of this disease, data regarding the status of PON-1 in COPD are ...
Jun Watanabe +2 more
doaj +1 more source
Separation and quantitative recovery of mouse serum arylesterase and carboxylesterase activity
Paraoxonase-1 (PON1) is known to be associated with high density lipoproteins. We optimized buffer conditions to obtain quantitative recovery of PON1 (arylesterase) activity and analyzed the distribution of PON1 in mice using a combination of size ...
Philip W. Connelly +2 more
doaj +1 more source
Extraction and characterization of Arylesterase enzyme from (peel and pulp) of Annona muricata fruit. [PDF]
The extraction of arylesterase from the aqueous extract of (peel and pulp) of Annona muricata fruit was conducted using different biochemical techniques.
Firdaws A. Almashhdani +2 more
doaj +1 more source
Depletion of B-cells with rituximab improves endothelial function and reduces inflammation among individuals with rheumatoid arthritis. [PDF]
BackgroundIndividuals with rheumatoid arthritis (RA) are at increased risk for cardiovascular disease, partly due to systemic inflammation and endothelial dysfunction.
Del Puerto, Gus +10 more
core +2 more sources

