Results 1 to 10 of about 29,702,919 (206)
Paraoxonase 1 and atherosclerosis [PDF]
Frontiers in Cardiovascular Medicine, 2023 Paraoxonase 1 (PON1), residing almost exclusively on HDL, was discovered because of its hydrolytic activity towards organophosphates. Subsequently, it was also found to hydrolyse a wide range of substrates, including lactones and lipid hydroperoxides ...
Paul N. Durrington +4 more
doaj +4 more sources
Phytochemicals as Modulators of Paraoxonase-1 in Health and Diseases
Antioxidants, 2022 Chronic diseases such as cardiovascular disease (CVD), atherosclerosis, chronic liver disease, and neurodegenerative diseases are major causes of mortality.
Amirhossein Sahebkar +2 more
exaly +6 more sources
Balkan Medical Journal, 2017 Background: Apolipoprotein A-1, paraoxonase-1 and paraoxonase-3 are antioxidant and anti-atherosclerotic structural high-density lipoprotein proteins that are mainly synthesized by the liver.
Gülben Sayılan Özgün +5 more
doaj +2 more sources
The Relationship between Cancer and Paraoxonase 1
Antioxidants, 2022 Extensive research has been carried out to understand and elucidate the mechanisms of paraoxonase 1 (PON1) in the development of diseases including cancer, cardiovascular diseases, neurological diseases, and inflammatory diseases.
Irma Martha Medina-Díaz +7 more
doaj +3 more sources
Antioxidants, 2023 The presence of a pro-oxidant state in patients with schizophrenia may account for the increased risk of atherosclerosis and cardiovascular disease in this group and supports the potential utility of circulating biomarkers of oxidative stress for risk ...
Angelo Zinellu +2 more
doaj +2 more sources
Preferential inhibition of paraoxonase activity of human paraoxonase 1 by negatively charged lipids
Journal of Lipid Research, 2004 To determine the causes responsible for a preferential decrease of paraoxonase activity, which has been observed in the serum of patients with cardiovascular diseases, the inactivation or inhibition of paraoxonase 1 (PON1) by various endogenous factors ...
Dai-Eun Sok, Su Duy Nguyen
exaly +3 more sources
The Iraqi Journal of Medical Sciences, 2022 Background: The use of labor induction to shorten the duration of a pregnancy has increased steadily during the last few decades. Paraoxonase 1 levels were observed to be higher in the oxytocin-induced group than in the spontaneous labor group ...
Sarah N. Ahmed, Ayla K. Ghalib
doaj +6 more sources
Paraoxonase 1 Activity and its Polymorphism in Type 2 Diabetic Nephropathy
Endocrinology Research and Practice, 2018 Objective: This study aims to investigate the role of paraoxonase 1 activity and Q192R polymorphism in the development of nephropathy in patients with Type 2 diabetes mellitus.
Mukund R. MOGAREKAR +2 more
doaj +1 more source
The Effects of Bioavailability-Enhanced Curcuminoids on Serum Paraoxonase-1 Activity in Patients with Metabolic Syndrome [PDF]
Journal of Cardio-Thoracic Medicine, 2021 Introduction: Metabolic syndrome (MetS) is characterised by a clustering of metabolic cardiovascular disease (CVD) risk factors that include: central obesity, impaired glucose metabolism, dyslipidaemia (hypertriglyceridemia, increased low-density ...
Atena Raee +7 more
doaj +1 more source
Serum paraoxonase 1 activity and protein N-homocysteinylation in primary human endometrial cancer
Tumor Biology, 2018 Paraoxonase 1 plays an important role in protection from oxidative stress and also decomposes homocysteine thiolactone, the toxic metabolite of homocysteine.
Krzysztof Gałczyński +5 more
doaj +1 more source