Paraoxonase 1 and atherosclerosis. [PDF]
Front Cardiovasc Med, 2023 Paraoxonase 1 (PON1), residing almost exclusively on HDL, was discovered because of its hydrolytic activity towards organophosphates. Subsequently, it was also found to hydrolyse a wide range of substrates, including lactones and lipid hydroperoxides ...
Durrington PN, Bashir B, Soran H.
europepmc +4 more sources
The Relationship between Cancer and Paraoxonase 1
Antioxidants, 2022 Extensive research has been carried out to understand and elucidate the mechanisms of paraoxonase 1 (PON1) in the development of diseases including cancer, cardiovascular diseases, neurological diseases, and inflammatory diseases.
Irma Martha Medina-Díaz +7 more
doaj +3 more sources
Paraoxonase/Arylesterase Activity of Serum Paraoxonase-1 and Schizophrenia: A Systematic Review and Meta-Analysis. [PDF]
Antioxidants (Basel), 2023 The presence of a pro-oxidant state in patients with schizophrenia may account for the increased risk of atherosclerosis and cardiovascular disease in this group and supports the potential utility of circulating biomarkers of oxidative stress for risk ...
Zinellu A, Sedda S, Mangoni AA.
europepmc +2 more sources
Associations of PON1 and genetic ancestry with obesity in early childhood. [PDF]
, 2013 Obesity in children has become an epidemic in the U.S. and is particularly prominent in minority populations such as Mexican-Americans. In addition to physical activity and diet, genetics also plays a role in obesity etiology. A few studies in adults and
Beckman, Kenneth +4 more
core +10 more sources
The Iraqi Journal of Medical Sciences, 2022 Background: The use of labor induction to shorten the duration of a pregnancy has increased steadily during the last few decades. Paraoxonase 1 levels were observed to be higher in the oxytocin-induced group than in the spontaneous labor group ...
Sarah N. Ahmed, Ayla K. Ghalib
doaj +6 more sources
Balkan Medical Journal, 2017 Background: Apolipoprotein A-1, paraoxonase-1 and paraoxonase-3 are antioxidant and anti-atherosclerotic structural high-density lipoprotein proteins that are mainly synthesized by the liver.
Gülben Sayılan Özgün +5 more
doaj +1 more source
Serum biomarkers of oxidative stress in dogs with idiopathic inflammatory bowel disease [PDF]
, 2017 © 2017 Elsevier Ltd. This document is the published version of a published work that appeared in final form in Veterinary Journal. To access the final edited and published work see: https://doi.org/10.1016/j.tvjl.2017.02.003The objective of this ...
Allenspach, K +5 more
core +2 more sources
Oral chondroitin sulfate and prebiotics for the treatment of canine Inflammatory Bowel Disease: a randomized, controlled clinical trial [PDF]
, 2016 BACKGROUND Canine inflammatory bowel disease (IBD) is a chronic enteropathy of unknown etiology, although microbiome dysbiosis, genetic susceptibility, and dietary and/or environmental factors are hypothesized to be involved in its pathogenesis. Since
A Ghiselli +51 more
core +6 more sources
Extended-release niacin increases anti-apolipoprotein A-I antibodies that block the antioxidant effect of high-density lipoprotein-cholesterol: the EXPLORE clinical trial. [PDF]
, 2017 Extended-release niacin (ERN) is the most effective agent for increasing high-density lipoprotein-cholesterol (HDL-C). Having previously identified anti-HDL antibodies, we investigated whether ERN affected the antioxidant capacity of HDL and whether ERN ...
Alves, JD +6 more
core +1 more source
Paraoxonase 1 Activity and its Polymorphism in Type 2 Diabetic Nephropathy
Endocrinology Research and Practice, 2018 Objective: This study aims to investigate the role of paraoxonase 1 activity and Q192R polymorphism in the development of nephropathy in patients with Type 2 diabetes mellitus.
Mukund R. MOGAREKAR +2 more
doaj +1 more source