Results 21 to 30 of about 27,544,016 (212)
Biomolecules, 2021 Infectious and many non-infectious diseases share common molecular mechanisms. Among them, oxidative stress and the subsequent inflammatory reaction are of particular note.
J. Camps +7 more
semanticscholar +1 more source
Scientific Reports, 2021 Paraoxonase 1 (PON1) is known for preventing atherosclerosis through lipid-modifying features, antioxidant activity, anti-inflammatory, anti-apoptosis, anti-thrombosis, and anti-adhesion properties.
A. Grzegorzewska +9 more
semanticscholar +1 more source
Paraoxonase 1, B Vitamins Supplementation, and Mild Cognitive Impairment
Journal of Alzheimer's Disease, 2021 Background: Identification of modifiable risk factors that affect cognitive decline is important for the development of preventive and treatment strategies.
J. Perła-Kaján +7 more
semanticscholar +1 more source
Paraoxonase 1 in neurological disorders [PDF]
Redox Report, 2013 Paroxonase 1 displays multiple physiological activities that position it as a putative player in the pathogenesis of neurological disorders. Here we reviewed the literature focusing on the role of paraoxonase 1 (PON1) as a factor in the risk of stroke and the major neurodegenerative diseases.
Teresita, Menini, Alejandro, Gugliucci
openaire +2 more sources
Solubilization and Humanization of Paraoxonase-1 [PDF]
Journal of Lipids, 2012 Paraoxonase-1 (PON1) is a serum protein, the activity of which is related to susceptibility to cardiovascular disease and intoxication by organophosphorus (OP) compounds. It may also be involved in innate immunity, and it is a possible lead molecule in the development of a catalytic bioscavenger of OP pesticides and nerve agents.
Mohosin Sarkar +8 more
openaire +2 more sources
Myeloperoxidase-induced modification of HDL by isolevuglandins inhibits paraoxonase-1 activity
Journal of Biological Chemistry, 2021 Reduced activity of paraoxonase 1 (PON1), a high-density lipoprotein (HDL)-associated enzyme, has been implicated in the development of atherosclerosis.
Geetika Aggarwal +9 more
semanticscholar +1 more source
Paraoxonase 1 and Chronic Obstructive Pulmonary Disease: A Meta-Analysis
Antioxidants, 2021 Oxidative stress is a driving factor in the pathophysiology of chronic obstructive pulmonary disease (COPD). While paraoxonase 1 (PON1) is an antioxidant enzyme and a potential biomarker of this disease, data regarding the status of PON-1 in COPD are ...
J. Watanabe, K. Kotani, A. Gugliucci
semanticscholar +1 more source
Paraoxonase 1 status in the Thai population [PDF]
Journal of Human Genetics, 2005 Human serum paraoxonase 1 (PON1), a high-density lipoprotein (HDL)-associated enzyme, has been shown to reduce the oxidation of low-density lipoprotein (LDL) and HDL by degrading lipid peroxides. This property of PON1 accounts for its ability to protect against atherosclerosis.
Wimon, Phuntuwate +4 more
openaire +2 more sources
Disease Markers, 2022 Aim To review and compare the PON-1 arylesterase activity between coronary artery disease (CAD) and non-CAD patients. Methods Data were obtained by searching MEDLINE and Scopus for all investigations published between January 1, 2000 and March 1, 2021 ...
M. Zuin +9 more
semanticscholar +1 more source
Balkan Medical Journal, 2017 Background: Apolipoprotein A-1, paraoxonase-1 and paraoxonase-3 are antioxidant and anti-atherosclerotic structural high-density lipoprotein proteins that are mainly synthesized by the liver.
Gülben Sayılan Özgün +5 more
doaj +1 more source