Results 41 to 50 of about 27,544,016 (212)

Study of Paraoxonase 1 (PON1) Activity as an Independent Risk Factor in Coronary Artery Disease [PDF]

National Journal of Laboratory Medicine, 2013
Background: Coronary Artery Disease is the major cause of mortality and morbidity worldwide. Human serum paraoxonase-1 is a high density lipoprotein bound enzyme exhibiting antiatherogenic properties.
Sangita M. Patil, Mangesh P. Banker, Ramchandra K. Padalkar, Abhijit P. Pathak, Shital Ghodke, Anjali S. Phatake , Sonali S. Bhagat, Rahul A. Ghone   +7 more
doaj   +1 more source

Study the levels of Leptin, and Adiponectin with Paraoxonase in Obese Individuals (male & female)

Tikrit Journal of Pure Science, 2023
Obesity is a well-known risk factor of metabolic complications and cardiovascular disease. Associations between anthropometric measurements and fat distribution and risk factors  for cardiovascular disease have been demonstrated in several populations.
Entedhar R. Sarhat
doaj   +1 more source

Paraoxonase 1 as an important antiatherogenic agent

Journal of Education, Health and Sport, 2019
The inverse relationship between High Density Lipoproteins (HDL) level and risk of ischaemic heart disease was proved by many epidemiological studies. Although the main mechanism of antiatherogenic activity of HDL is a reverse transport of cholesterol ...
Ewa Lidia Krzewicka-Romaniuk, Dagna Agnieszka Siedlecka, Anna Warpas, Grażyna Wójcicka   +3 more
doaj   +3 more sources

Regulation of Hepatic Paraoxonase-1 Expression [PDF]

Journal of Lipids, 2012
Serum paraoxonase-1 (PON1) is a member of the paraoxonases family (PON1, PON2, and PON3). PON1 is synthesized and secreted by the liver, and in circulation it is associated with HDL. PON1 has antioxidative properties, which are associated with the enzyme’s capability to decrease oxidative stress in atherosclerotic lesions and to attenuate ...
openaire   +2 more sources

Inhibitory role of long non‐coding RNA OIP5‐AS1 in rheumatoid arthritis progression through the microRNA‐448–paraoxonase 1–toll‐like receptor 3–nuclear factor κB axis

Experimental Physiology, 2020
What is the central question of this study? What are the functions of long non‐coding (lnc) RNA OIP5‐AS1 in development of rheumatoid arthritis inflammation and what is the molecular mechanism? What is the main finding and its importance? LncRNA OIP5‐AS1
Pingying Qing, Yi Liu
semanticscholar   +1 more source

The paraoxonase 1, 2 and 3 in humans

Biochemia Medica, 2011
The paraoxonase gene family in humans includes three members: PON1, PON2 and PON3. The products of those three genes are the following enzymes: paraoxonase 1 (PON1), paraoxonase 2 (PON2) and paraoxonase 3 (PON3). PON1 is mainly associated with a high density lipoprotein (HDL). A small amount of this enzyme is also bound to very low-density lipoprotein (
Grdic Rajkovic, Marija, Rumora, Lada, Barisic, Karmela   +2 more
openaire   +5 more sources

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah, Sangmee S. Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

Induction of the Paraoxonase-1 Gene Expression by Resveratrol [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2004
Objective— The human paraoxonase-1 (PON-1) is a high-density lipoprotein-associated enzyme, mainly secreted by the liver, that displays protective properties toward cardiovascular disease and organophosphate intoxication.
Cédric, Gouédard, Robert, Barouki, Yannick, Morel   +2 more
openaire   +2 more sources

Evaluation of Lipid metabolizing enzymes: Paraxonase1(PON1) and Lecithin Cholesterol acyltransferase (LCAT) activities in children with nephrotic syndrome

Baghdad Journal of Biochemistry and Applied Biological Sciences, 2021
Background: The most common glomerular disorder in children is nephrotic syndrome, associated with high morbidity despite notable advances in its treatment. Many of the nephrotic syndrome complications, including the increased risk of atherosclerosis and
Raghad Jamal Ali , Rayah Sulaiman Baban , Shatha Hussain Ali   +2 more
doaj  

Dietary cholesterol increases paraoxonase 1 enzyme activity

Journal of Lipid Research, 2012
HDL-associated paraoxonase 1 (PON1) activity has been consistently associated with cardiovascular and other diseases. Vitamins C and E intake have previously been positively associated with PON1 in a subset of the Carotid Lesion Epidemiology and Risk ...
Daniel S. Kim, Amber A. Burt, Jane E. Ranchalis, Rebecca J. Richter, Julieann K. Marshall, Karen S. Nakayama, Ella R. Jarvik, Jason F. Eintracht, Elisabeth A. Rosenthal, Clement E. Furlong, Gail P. Jarvik   +10 more
doaj   +1 more source