Results 41 to 50 of about 16,430 (217)

Antibodies against HDL Components in Ischaemic Stroke and Coronary Artery Disease [PDF]

, 2018
Quantitative and qualitative defects of high-density lipoprotein (HDL) are important in atherogenesis. In this study, we investigated whether antibodies against HDL components had additional value to conventional cardiovascular risk factors for the ...
Alves, JD, Amaral, M, Ames, P, Batuca, J, Favas, C, Justino, G, Papoila, A   +6 more
core   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Low Serum Paraoxonase-1 Lactonase and Arylesterase Activities in Obese Children and Adolescents

Romanian Journal of Laboratory Medicine, 2015
Serum paraoxonase-1 (PON1) binds mainly to high density lipoproteins (HDLs) and protects low density lipoproteins (LDLs) against oxidation. While paraoxonase and arylesterase activities are traditionally assayed, lactonase activity, accounting for ...
Sandor Raluca, Leucuta Daniel, Dronca Eleonora, Niculae Alexandru, Cret Victoria, Silaghi Ciprian, Suciu Soimita   +6 more
doaj   +1 more source

Chronic, Environmentally Relevant PM2.5 Exposure Exacerbates Metabolic Dysfunction‐Associated Steatotic Liver Disease and Early‐Stage Renal Dysfunction in a Rodent Model

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT While epidemiological studies link fine particulate matter (PM2.5) exposure to metabolic dysfunction‐associated steatotic liver disease (MASLD) and renal dysfunction, a translational gap exists, as most animal models utilize acute, high‐dose exposures that poorly reflect chronic, moderate‐level human scenarios.
Yi‐Siao Chen, Hugo You‐Hsien Lin, Chien‐Tzu Lin, Si‐Hua Huang, Ming‐Lun Yeh, Ming‐Lung Yu, Jin‐Ching Lee, Yao‐Chi Chung, Wei‐Ming Li, Ching‐Chia Li, Shiu‐Feng Huang, Chia‐Hung Yen   +11 more
wiley   +1 more source

Serum Paraoxonase-1 Activity in Prostate Cancer Patients Treated with Brachytherapy as a Measure of Irradiation Efficacy

Antioxidants, 2023
We investigated changes in the activity of antioxidant paraoxonase-1 (PON1) in patients with prostate cancer (PCa) undergoing radiotherapy (RT), as well as the relationship of the PON1 activity with the degree of PCa advancement.
Dorota Olszewska-Słonina, Miłosz Jasiński   +1 more
doaj   +1 more source

Relationship of serum paraoxonase 1 activity and paraoxonase 1 genotype to risk of systemic lupus erythematosus [PDF]

Arthritis & Rheumatism, 2006
AbstractObjectiveLow serum paraoxonase 1 (PON1) activity determined with paraoxon as substrate has been found to be associated with coronary artery disease. This study was undertaken to examine the relationship of PON1 activity and genotype to risk of systemic lupus erythematosus (SLE).MethodsThe impact of 7 PON1 single‐nucleotide polymorphisms (SNPs ...
Laura M, Tripi, Susan, Manzi, Qi, Chen, Margaret, Kenney, Penny, Shaw, Amy, Kao, Franklin, Bontempo, Candace, Kammerer, M Ilyas, Kamboh   +8 more
openaire   +2 more sources

Paraoxonase 1 Activity in Endocrine Diseases

Endocrinology Research and Practice, 2011
Paraoxonase is an esterase bound to high-density lipoproteins which by metabolizing lipid peroxides, prevents their accumulation on low-density lipoproteins. It also hydrolyzes various organophosphorus compounds.
Özlem Tarçın, Dilek Gogas Yavuz
doaj   +2 more sources

Evaluation of Lipid metabolizing enzymes: Paraxonase1(PON1) and Lecithin Cholesterol acyltransferase (LCAT) activities in children with nephrotic syndrome

Baghdad Journal of Biochemistry and Applied Biological Sciences, 2021
Background: The most common glomerular disorder in children is nephrotic syndrome, associated with high morbidity despite notable advances in its treatment. Many of the nephrotic syndrome complications, including the increased risk of atherosclerosis and
Raghad Jamal Ali , Rayah Sulaiman Baban , Shatha Hussain Ali   +2 more
doaj  

High-density lipopoprotein antioxidant capacity, subpopulation distribution and paraoxonase-1 activity in patients with systemic lupus erythematosus [PDF]

, 2016
BACKGROUND: The causes of increased cardiovascular risk in systemic lupus erythematosus (SLE) are not understood thoroughly, although presence of traditional cardiovascular risk factors and disease-specific agents were also proposed.
György Paragh, Hajnalka Lőrincz, Ildikó Seres, Krisztina Gaál, Mariann Harangi, Péter Fülöp, Tünde Tarr, Viktor Borbás   +7 more
core   +1 more source

Surgical impact of laparoscopic and laparotomic elective ovariectomy on inflammatory and oxidative stress biomarkers in anestrus dogs

Veterinary Surgery, EarlyView.
Abstract Objective To compare the systemic inflammatory and oxidative stress responses after elective ovariectomy via open surgery (OPEN) or laparoscopy (LAP) in anestrus bitches. Study design Prospective, blinded, randomized clinical trial. Animals A total of 26 healthy bitches.
Alfonso Calabria, Chiara Del Prete, Maria Pia Pasolini, Veronica Palumbo, Maria Anna Nappo, Silvia Ammirati, Davide Ciccarelli, Fabiana Micieli, Michal Andrzej Kosior, Carmine Carbone, Natascia Cocchia   +10 more
wiley   +1 more source