Results 61 to 70 of about 16,430 (217)
Mutual Influences between Nitric Oxide and Paraoxonase 1 [PDF]
One of the best consolidated paradigms in vascular pharmacology is that an uncontrolled excess of oxidizing chemical species causes tissue damage and loss of function in the endothelial and subendothelial layers. The fact that high-density lipoproteins play an important role in preventing such an imbalance is integrated into that concept, for which the
Moya, Carlos +2 more
openaire +3 more sources
Paraoxonase 1 Phenotype and Paraoxonase Activity in Asthmatic Patients
Oxidative stress is involved in the pathogenesis of asthma. Paraoxonase 1 (PON1) and arylesterase are esterase enzymes displaying antioxidant characteristics.
Nurhan Sarioglu +4 more
doaj
Serum Paraoxonase-1 Activity and Paraoxonase Q192 Gene Polymorphism in a Young, Healthy Population
Objective: Paraoxonase-1 (PON1) enzyme and PON Q192R gene polymorphism are associated with atherosclerosis in many middle-aged individuals and high populations at risk of cardiovascular disease. This study aimed to determine serum PON-1 and arylesterase (
Dilek GOGAS YAVUZ +5 more
doaj +1 more source
In this study, a highly robust N‐glycoproteomics (HRN) platform with a newly developed match‐between‐run scheme is used for biomarker discovery. This study proposes a protein‐centric strategy to prioritize proteins susceptible to aberrant glycosylation.
Lei Liu +15 more
wiley +1 more source
We aimed to investigate the relationship between serum paraoxonase-1 (PON1) and paraoxonase-3 (PON3) levels and activities with hemoglobin A1c (HbA1c), serum fasting blood glucose, lipid profile, and oxidative stress in patients with type 2 diabetes ...
Ucar Yagcı Yagmur +3 more
doaj +1 more source
Environmental Exposures and Parkinson's Disease. [PDF]
Parkinson's disease (PD) affects millions around the world. The Braak hypothesis proposes that in PD a pathologic agent may penetrate the nervous system via the olfactory bulb, gut, or both and spreads throughout the nervous system. The agent is unknown,
Litvan, Irene, Nandipati, Sirisha
core +2 more sources
ABSTRACT Background and Aims Atherosclerosis (AS), a major cause of cardiovascular mortality, involves chronic inflammation mediated by transcription factors such as NF‐κB, PPARs, and AP‐2α. Beyond its antiplatelet role, aspirin exerts anti‐inflammatory effects that may influence these molecular pathways.
Mojtaba Aghaei +6 more
wiley +1 more source
Background and Objective: Paraoxonase-1 is an important factor in preventing lipid oxidation and formation of oxidized low-density lipoprotein. There are conflicting reports on the impact of physical activity on serum level of Paraoxonase-1.
Amouzad Mahdirejei T +3 more
doaj
Multiomics Research Strategies in Cancer: A Growing and Innovative Field
This review highlights multiomics strategies in cancer research, focusing on integration methods from genomics to microbiomics. Using colorectal cancer as a key example, it discusses biomarker discovery, data integration via deep learning, and the roles of single‐cell and spatial omics.
Zhenhua Du +8 more
wiley +1 more source
The Effect of Atherogenic Diet with or without Enzyme Inhibitors on the Incidence and Progress of Atherosclerosis in Rabbits [PDF]
PON1 (Paraoxonase – 1) is an esterase enzyme which is associated with high density lipoprotein (HDL). The enzyme prevents the peroxidation of low density lipoprotein (LDL).
Masouad Pezeshkian +6 more
doaj

