Results 61 to 70 of about 107,672,034 (158)

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

open access: yesArthritis Care &Research, Volume 78, Issue 9, Page 1112-1122, September 2026.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah   +8 more
wiley   +1 more source

Paraoxonase 1 Phenotype and Paraoxonase Activity in Asthmatic Patients

open access: yes, 2020
Oxidative stress is involved in the pathogenesis of asthma. Paraoxonase 1 (PON1) and arylesterase are esterase enzymes displaying antioxidant characteristics.
EREL, FUAT   +4 more
core  

PARAOXONASE 1 ACTIVITIES IN FIRST TRIMESTER MISCARRIAGES [PDF]

open access: yes, 2021
Aim: Miscarriages are becoming increasingly important problem nowadays. First trimester pregnancy loss frequency in women of reproductive age is increasing.
Dilek ERDEM   +3 more
core   +1 more source

Cardiovascular disease incidence and cancer risk in two large European prospective cohorts

open access: yesInternational Journal of Cancer, Volume 159, Issue 5, Page 1139-1152, 1 September 2026.
What's new? Cardiovascular disease (CVD) and cancer share risk factors and biological mechanisms, raising questions about potential associations between the two, particularly regarding CVD duration and cancer onset. Whether CVD influences subsequent cancer risk, however, remains inconclusive.
Emma Fontvieille   +25 more
wiley   +1 more source

Effect of four weeks of endurance training on serum level of paraoxonase-1 and lipid profile in non-athlete obese men

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2014
Background and Objective: Paraoxonase-1 is an important factor in preventing lipid oxidation and formation of oxidized low-density lipoprotein. There are conflicting reports on the impact of physical activity on serum level of Paraoxonase-1.
Amouzad Mahdirejei T   +3 more
doaj  

Quinoline and Phthalimide Substituted Silicon Phthalocyanines as Multi‐Target Inhibitors of Cholinesterases and Carbonic Anhydrases

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Two novel axially substituted silicon phthalocyanines were synthesized and characterized. Compound 2a exhibited significantly enhanced inhibition of AChE, BChE, hCA I and hCA II, supported by molecular docking and SAR analysis, highlighting its potential as a multifunctional enzyme inhibitor with promising biological activity.
Seda Ünlü   +3 more
wiley   +1 more source

The Effect of Atherogenic Diet with or without Enzyme Inhibitors on the Incidence and Progress of Atherosclerosis in Rabbits [PDF]

open access: yesJournal of Cardiovascular and Thoracic Research, 2011
PON1 (Paraoxonase – 1) is an esterase enzyme which is associated with high density lipoprotein (HDL). The enzyme prevents the peroxidation of low density lipoprotein (LDL).
Masouad Pezeshkian   +6 more
doaj  

Therapeutic Potential of Chickpea‐Derived Bioactives: A Review With Perspective of Different In Vitro, Animal, and Human Studies

open access: yesLegume Science, Volume 8, Issue 3, September 2026.
ABSTRACT Chickpea (Cicer arietinum L.) is an important dietary legume worldwide and provides micronutrients and phytochemicals, including phenolics, flavonoids, carotenoids, bioactive peptides, dietary fiber, and resistant starch. This narrative review summarizes evidence from in vitro, animal, and human studies on the potential health relevance of ...
Rohama Shahid   +4 more
wiley   +1 more source

Evaluation of paraoxonase, malondialdehyde, and lipoprotein levels in patients with asymptomatic cholelithiasis

open access: yesThe Saudi Journal of Gastroenterology, 2014
Background/Aim: To compare lipoprotein and malondialdehyde levels and paraoxonase-1 activity between subjects with asymptomatic cholelithiasis and controls.
Aytac Atamer   +3 more
doaj   +1 more source

Paraoxonase 1 (PON1) status and substrate hydrolysis [PDF]

open access: yesToxicology and Applied Pharmacology, 2009
Paraoxonase 1 (PON1) hydrolyzes a number of organophosphorus (OP) compounds including insecticides and nerve agents. The in vivo efficacy of PON1 to protect against a specific OP exposure depends on the catalytic efficiency of hydrolysis. The Q192R polymorphism affects the catalytic efficiency of hydrolysis of some substrates and not others. While PON1(
Rebecca J, Richter   +2 more
openaire   +2 more sources

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