Results 61 to 70 of about 16,430 (217)

Mutual Influences between Nitric Oxide and Paraoxonase 1 [PDF]

open access: yesAntioxidants, 2019
One of the best consolidated paradigms in vascular pharmacology is that an uncontrolled excess of oxidizing chemical species causes tissue damage and loss of function in the endothelial and subendothelial layers. The fact that high-density lipoproteins play an important role in preventing such an imbalance is integrated into that concept, for which the
Moya, Carlos   +2 more
openaire   +3 more sources

Paraoxonase 1 Phenotype and Paraoxonase Activity in Asthmatic Patients

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2015
Oxidative stress is involved in the pathogenesis of asthma. Paraoxonase 1 (PON1) and arylesterase are esterase enzymes displaying antioxidant characteristics.
Nurhan Sarioglu   +4 more
doaj  

Serum Paraoxonase-1 Activity and Paraoxonase Q192 Gene Polymorphism in a Young, Healthy Population

open access: yesEndocrinology Research and Practice, 2021
Objective: Paraoxonase-1 (PON1) enzyme and PON Q192R gene polymorphism are associated with atherosclerosis in many middle-aged individuals and high populations at risk of cardiovascular disease. This study aimed to determine serum PON-1 and arylesterase (
Dilek GOGAS YAVUZ   +5 more
doaj   +1 more source

A Protein‐Centric Strategy Coupled with Match‐Between‐Run Glycoproteomics Enables Discovery of Robust Site‐Specific Glycan Biomarkers for Hepatocellular Carcinoma

open access: yesAdvanced Science, Volume 13, Issue 22, 17 April 2026.
In this study, a highly robust N‐glycoproteomics (HRN) platform with a newly developed match‐between‐run scheme is used for biomarker discovery. This study proposes a protein‐centric strategy to prioritize proteins susceptible to aberrant glycosylation.
Lei Liu   +15 more
wiley   +1 more source

Relationship of paraoxonase-1 and paraoxonase-3 with routine laboratory tests and oxidative stress in type 2 diabetes mellitus

open access: yesTürk Biyokimya Dergisi
We aimed to investigate the relationship between serum paraoxonase-1 (PON1) and paraoxonase-3 (PON3) levels and activities with hemoglobin A1c (HbA1c), serum fasting blood glucose, lipid profile, and oxidative stress in patients with type 2 diabetes ...
Ucar Yagcı Yagmur   +3 more
doaj   +1 more source

Environmental Exposures and Parkinson's Disease. [PDF]

open access: yes, 2016
Parkinson's disease (PD) affects millions around the world. The Braak hypothesis proposes that in PD a pathologic agent may penetrate the nervous system via the olfactory bulb, gut, or both and spreads throughout the nervous system. The agent is unknown,
Litvan, Irene, Nandipati, Sirisha
core   +2 more sources

Potential Effects of Aspirin on Transcription Factors Related to the Inflammation in Atherosclerosis: A Systematic Review

open access: yesHealth Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims Atherosclerosis (AS), a major cause of cardiovascular mortality, involves chronic inflammation mediated by transcription factors such as NF‐κB, PPARs, and AP‐2α. Beyond its antiplatelet role, aspirin exerts anti‐inflammatory effects that may influence these molecular pathways.
Mojtaba Aghaei   +6 more
wiley   +1 more source

Effect of four weeks of endurance training on serum level of paraoxonase-1 and lipid profile in non-athlete obese men

open access: yesمجله دانشگاه علوم پزشکی گرگان, 2014
Background and Objective: Paraoxonase-1 is an important factor in preventing lipid oxidation and formation of oxidized low-density lipoprotein. There are conflicting reports on the impact of physical activity on serum level of Paraoxonase-1.
Amouzad Mahdirejei T   +3 more
doaj  

Multiomics Research Strategies in Cancer: A Growing and Innovative Field

open access: yesMedComm, Volume 7, Issue 4, April 2026.
This review highlights multiomics strategies in cancer research, focusing on integration methods from genomics to microbiomics. Using colorectal cancer as a key example, it discusses biomarker discovery, data integration via deep learning, and the roles of single‐cell and spatial omics.
Zhenhua Du   +8 more
wiley   +1 more source

The Effect of Atherogenic Diet with or without Enzyme Inhibitors on the Incidence and Progress of Atherosclerosis in Rabbits [PDF]

open access: yesJournal of Cardiovascular and Thoracic Research, 2011
PON1 (Paraoxonase – 1) is an esterase enzyme which is associated with high density lipoprotein (HDL). The enzyme prevents the peroxidation of low density lipoprotein (LDL).
Masouad Pezeshkian   +6 more
doaj  

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