Results 61 to 70 of about 27,544,016 (212)

Sepsis in Dogs and Cats—Consensus Definition and Clinical Criteria

Journal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Sepsis is the clinical syndrome that results from the host response to severe or widespread infection and is a frequent cause of death in veterinary critical care settings. Rapid diagnosis aids early treatment initiation, and hence, how sepsis is defined and identified clinically has implications for patient outcomes.
Robert Goggs, Stefano Cortellini, Amy E. DeClue, Massimo Giunti, Kate Hopper, Julie M. Menard, Rodrigo C. Rabelo, Elizabeth A. Rozanski, Claire R. Sharp, Deborah C. Silverstein, Virginia Sinnott‐Stutzman, Giacomo Stanzani, John Bourgeois, Erik Fausak   +13 more
wiley   +1 more source

Environmental Pesticide Exposure in the Etiology of Pediatric Brain Tumors and Leukemia: A Scoping Review of Epidemiological Studies

International Journal of Cancer, Volume 159, Issue 6, Page 1360-1384, 15 September 2026.
ABSTRACT Pediatric cancer is a significant cause of morbidity and mortality in children. The etiologies of pediatric cancer are largely unknown, but environmental pesticide exposures are likely to contribute. Chronic low‐dose exposure to pesticide mixtures through drinking water is a growing concern in agricultural communities.
Grace N. VanDeSteeg, Alyssa R. Russum, Matthew R. Sandbulte, Eleanor G. Rogan, Martha G. Rhoades   +4 more
wiley   +1 more source

Cardiovascular disease incidence and cancer risk in two large European prospective cohorts

International Journal of Cancer, Volume 159, Issue 5, Page 1139-1152, 1 September 2026.
What's new? Cardiovascular disease (CVD) and cancer share risk factors and biological mechanisms, raising questions about potential associations between the two, particularly regarding CVD duration and cancer onset. Whether CVD influences subsequent cancer risk, however, remains inconclusive.
Emma Fontvieille, Vivian Viallon, Laia Peruchet‐Noray, Quan Gan, N. Charlotte Onland‐Moret, Yvonne Koop, Anne Tjønneland, Nicola Patricia Bondonno, Verena Katzke, Rudolf Kaaks, Matthias B. Schulze, Catarina Schiborn, Calogero Saieva, Vittorio Simeon, Claudia Agnoli, Rosario Tumino, Fulvio Ricceri, Leila Luján‐Barroso, Maria‐José Sánchez, Conchi Moreno‐Iribas, Konstantinos K. Tsilidis, Marc J. Gunter, Adam Butterworth, Elio Riboli, Heinz Freisling, Pietro Ferrari   +25 more
wiley   +1 more source

Paraoxonase 1 Phenotype and Paraoxonase Activity in Asthmatic Patients

Iranian Journal of Allergy, Asthma and Immunology, 2015
Oxidative stress is involved in the pathogenesis of asthma. Paraoxonase 1 (PON1) and arylesterase are esterase enzymes displaying antioxidant characteristics.
Nurhan Sarioglu, Adnan Adil Hismiogullari, Fuat Erel, Dudu Demir, Nahit Gencer   +4 more
doaj  

Serum Paraoxonase-1 Activity and Paraoxonase Q192 Gene Polymorphism in a Young, Healthy Population

Endocrinology Research and Practice, 2021
Objective: Paraoxonase-1 (PON1) enzyme and PON Q192R gene polymorphism are associated with atherosclerosis in many middle-aged individuals and high populations at risk of cardiovascular disease. This study aimed to determine serum PON-1 and arylesterase (
Dilek GOGAS YAVUZ, Özlem ÜSTAY, Palmet GÜN ATAK, Ahu TELLİ, Tuğçe APAYDIN, Önder ŞİRİKÇİ   +5 more
doaj   +1 more source

Therapeutic Potential of Chickpea‐Derived Bioactives: A Review With Perspective of Different In Vitro, Animal, and Human Studies

Legume Science, Volume 8, Issue 3, September 2026.
ABSTRACT Chickpea (Cicer arietinum L.) is an important dietary legume worldwide and provides micronutrients and phytochemicals, including phenolics, flavonoids, carotenoids, bioactive peptides, dietary fiber, and resistant starch. This narrative review summarizes evidence from in vitro, animal, and human studies on the potential health relevance of ...
Rohama Shahid, Maria Maqsood, Nimrah Ashraf, Farzeen Asghar, Nauman Khalid   +4 more
wiley   +1 more source

Relationship of paraoxonase-1 and paraoxonase-3 with routine laboratory tests and oxidative stress in type 2 diabetes mellitus

Türk Biyokimya Dergisi
We aimed to investigate the relationship between serum paraoxonase-1 (PON1) and paraoxonase-3 (PON3) levels and activities with hemoglobin A1c (HbA1c), serum fasting blood glucose, lipid profile, and oxidative stress in patients with type 2 diabetes ...
Ucar Yagcı Yagmur, Yılmaz Bulbul Buket, Sut Necdet, Ozgun Eray   +3 more
doaj   +1 more source

Gadolinium-based contrast agents: in vitro paraoxonase 1 inhibition, in silico studies

Drug and chemical toxicology (New York, N.Y. 1978), 2019
Medications show their biological effects by interaction with enzymes, which have been known to play an essential role in the pathogenesis of many diseases.
Ş. Beydemir, Cüneyt Türkeş, A. Yalçın   +2 more
semanticscholar   +1 more source

The characterization of a new stabilized lactonase from the endophytic fungi Aspergillus pseudonomiae with anti‐bacterial and anti‐fungal properties

Protein Science, Volume 35, Issue 8, August 2026.
Abstract Microorganisms use diverse small‐molecule signals to coordinate behavior, supporting interspecies and interkingdom communication. These chemical dialogs shape fundamental biological processes and define interactions from cooperation to antagonism.
Dor Ben Tovim, Olena Trofimyuk, Elon Yariv, Gali Prag, Livnat Afriat‐Jurnou   +4 more
wiley   +1 more source

Paraoxonase-1 status in patients with hereditary hemochromatosis [PDF]

Journal of Lipid Research, 2013
Hereditary hemochromatosis (HH) is characterized by accumulation of iron, oxidative stress, inflammation, and fibrogenesis in liver tissue. In this setting, research on the protection afforded by intracellular antioxidants is of clinical relevance. Paraoxonase-1 (PON1) is an enzyme that degrades lipid peroxides.
MARTINELLI, Nicola, García Heredia A, Roca H, Aranda N, Arija V, Mackness B, Mackness M, BUSTI, Fabiana, Aragonès G, Pedro Botet J, PEDICA, Federica, CATALDO, Ivana, Marsillach J, Joven J, Girelli D, Camps J.   +15 more
openaire   +4 more sources