Results 71 to 80 of about 16,430 (217)

Potential neuroprotective and therapeutic agents and their mechanisms for irradiation‐induced brain injury

open access: yesIbrain, Volume 12, Issue 1, Page 96-122, Spring 2026.
In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard   +2 more
wiley   +1 more source

Evaluation of paraoxonase, malondialdehyde, and lipoprotein levels in patients with asymptomatic cholelithiasis

open access: yesThe Saudi Journal of Gastroenterology, 2014
Background/Aim: To compare lipoprotein and malondialdehyde levels and paraoxonase-1 activity between subjects with asymptomatic cholelithiasis and controls.
Aytac Atamer   +3 more
doaj   +1 more source

Association between diet and polymorphisms in individuals with statin-controlled dyslipidaemia grouped according to oxidative stress biomarkers [PDF]

open access: yes, 2012
The objective of this study was to investigate whether differences in diet and in single-nucleotide polymorphisms (SNPs) found in paraoxonase-1 (PON-1), 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR), cholesterol ester transfer protein (CETP ...
Barroso, Lucia Pereira   +5 more
core   +4 more sources

Defective high‐density lipoprotein lipoprotection in type 2 diabetes during acute myocardial infarction is rescued by apolipoprotein M/sphingosine‐1‐phosphate loading

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 3, Page 2175-2182, March 2026.
Abstract Aims Mortality of patients with type 2 diabetes (T2D) after acute myocardial infarction (AMI) is tremendous and massively increased compared to non‐T2D individuals. The reasons are unclear. High‐density lipoprotein (HDL) conducts lipoprotection during AMI, leading to improved outcomes.
Jens Vogt   +12 more
wiley   +1 more source

Total oxidant status, total antioxidant status, and paraoxonase and arylesterase activities during laparoscopic cholecystectomy

open access: yesClinics, 2010
INTRODUCTION: Laparoscopic cholecystectomy is the gold standard for the treatment of gallstone disease; however, adverse hemodynamic changes induced by increased intraabdominal pressure due to pneumoperitoneum are known to occur.
Hande Koksal, Sevil Kurban
doaj   +1 more source

Climate Change, Local Harvests and Marine Contamination: A Perspective on Cetacean Populations and Coastal Whaling Communities

open access: yesAquatic Conservation: Marine and Freshwater Ecosystems, Volume 36, Issue 2, February 2026.
ABSTRACT Cetaceans are indicators of ocean health, influence marine ecosystem dynamics and hold socio‐economic importance for coastal whaling communities. Yet whale–whaler relationships remain poorly understood and are increasingly compromised under the triple planetary crisis of climate change, biodiversity loss and pollution. Here, we briefly outline
Melissa A. McKinney, Jeremy J. Kiszka
wiley   +1 more source

Misunderstandings about paraoxonase-1

open access: yes, 2023
[No Abstract Available]
Mackness, Michael, Sozmen, Eser Y.
openaire   +1 more source

Genetic polymorphisms of paraoxonase 1 and susceptibility to atherogenesis [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2013
Introduction. Paraoxonase 1 (PON1) is a multifunctional enzyme associated with high-density lipoprotein particles (HDL). It is a cellular antioxidant that hydrolyses oxidized macromolecules, especially low-density lipoproteins (ox-LDL).
Grubiša Ivana   +5 more
doaj   +1 more source

Statins in Breast Cancer Therapy: Mechanistic Insights and Emerging Evidence

open access: yesCancer Innovation, Volume 5, Issue 1, February 2026.
Statins, particularly simvastatin, demonstrate potential as adjuvant agents in breast cancer treatment by disrupting tumour cell signalling and survival pathways. This review highlights emerging evidence supporting their repurposing for improved outcomes, especially in aggressive breast cancer subtypes.
Rohina Alim, H. M. Kasuni Akalanka
wiley   +1 more source

Alzheimer’s Disease and Paraoxonase 1 (PON1) Gene Polymorphisms [PDF]

open access: yesThe Open Biochemistry Journal, 2017
Background: Some studies have indicated that human paraoxonase 1 ( PON1 ) activity shows a polymorphic distribution. The aim of this study was to determine the distribution of PON1 polymorphism in ...
Saeidi, Mohsen   +3 more
openaire   +2 more sources

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