Results 81 to 90 of about 27,544,016 (212)

Ethnomedicinal Properties and Technological Challenges of Pomegranate Fruit as a Value‐Added Product

open access: yeseFood, Volume 7, Issue 3, June 2026.
This review aims to provide a comprehensive review of pomegranate (Punica granatum) as a nourishing powerhouse, focusing on its remarkable nutritional conformation, bioactive composites, and substantial health assistance. This emphasizes the adaptableness and developing demand in the functional food market, as it discovers the potential solicitations ...
Muhammad Tayyab Arshad   +5 more
wiley   +1 more source

Why Should Psychiatrists and Neuroscientists Worry about Paraoxonase 1?

open access: yesCurrent Neuropharmacology, 2019
Background: Nitro-oxidative stress (NOS) has been implicated in the pathophysiology of psychiatric disorders. The activity of the polymorphic antioxidant enzyme paraoxonase 1 (PON1) is altered in diseases where NOS is involved.
E. Moreira   +5 more
semanticscholar   +1 more source

Organ‐Dependent Antioxidant, Redox‐Modulating, and Lifespan Effects of Galanthus elwesii Extracts in Drosophila melanogaster

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
Aerial (leaves and flowers) and belowground (bulbs and roots) parts of Galanthus elwesii were extracted using water, 70% ethanol, and 80% methanol. Phytochemical analyses revealed organ‐ and solvent‐dependent variations in total phenolic and flavonoid contents, which were associated with differences in in vitro antioxidant activity determined by DPPH ...
Osman Ertan, Arif Ayar, Ebru Batı Ay
wiley   +1 more source

Dynamic changes of paraoxonase 1 activity towards paroxon and phenyl acetate during coronary artery surgery

open access: yesBMC Cardiovascular Disorders, 2017
Background Serum paraoxonase 1 (PON1), an enzyme associated with high – density lipoproteins (HDL) particles, inhibits the oxidation of serum lipoproteins and cell membranes.
Anna Wysocka   +6 more
doaj   +1 more source

Clinical outcomes of mitochondrial‐enhancing nutraceutical supplementation in psychiatric disorders: A systematic review

open access: yesGeneral Psychiatry, Volume 39, Issue 3, June 2026.
ABSTRACT Background Nutraceutical supplementation targeting mitochondrial function has been proposed as a beneficial therapeutic strategy to improve physical and mental health in psychiatric patients. Aims To summarise the results of studies evaluating nutraceutical supplementation targeting mitochondrial function in patients with psychiatric disorders.
Juan Tortajada   +9 more
wiley   +1 more source

Paraoxonase 1 gene polymorphisms in patients with type 2 diabetes mellitus

open access: yesУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2014
The article deals with the features of lipid metabolism in patients with type 2 diabetes - the carriers of different genotypes of paraoxonase 1 gene. Known that the enzyme paraoxonase 1 (PON1) plays a key role in the regulation of lipid peroxidation and ...
M. V. Kim   +4 more
doaj   +1 more source

RAGE Re‐Expressed at Myofibre Level Drives Muscle Wasting in Cancer Conditions

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 3, June 2026.
ABSTRACT Background Cancer cachexia (CC) is a highly debilitating syndrome characterized by loss of body and muscle weight affecting most advanced cancer patients. The receptor for advanced glycation end‐products (RAGE) is expressed by several cell types and sustains the inflammatory response in acute and chronic diseases. Total ablation of RAGE (Ager−/
Sara Chiappalupi   +10 more
wiley   +1 more source

Ascorbic acid partly antagonizes resveratrol mediated heme oxygenase-1 but not paraoxonase-1 induction in cultured hepatocytes - role of the redox-regulated transcription factor Nrf2

open access: yesBMC Complementary and Alternative Medicine, 2011
Background Both resveratrol and vitamin C (ascorbic acid) are frequently used in complementary and alternative medicine. However, little is known about the underlying mechanisms for potential health benefits of resveratrol and its interactions with ...
Hori Osamu   +9 more
doaj   +1 more source

The importance of longitudinal evaluation using DAT‐SPECT in organophosphate‐induced toxic parkinsonism

open access: yesPsychiatry and Clinical Neurosciences Reports, Volume 5, Issue 2, June 2026.
We performed longitudinal evaluation using magnetic resonance imaging (MRI) and dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) in a case of organophosphate‐induced toxic parkinsonism. Fluid‐attenuated inversion recovery (FLAIR) images showed bilateral striatal hyperintensity in the acute phase, followed by reduction of ...
Shuhei Nakao   +6 more
wiley   +1 more source

The Antipsychotic Aripiprazole Induces Cytotoxicity in Bladder Cancer Cells While Preserving Urothelial and Bladder Function

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
Current bladder cancer therapies can cause toxicity and bladder dysfunction. Brief intravesical‐like aripiprazole exposure reduced bladder cancer cell viability and was associated with redox stress and caspase‐3 activation, while ex vivo findings suggested preserved bladder structure and function, warranting further investigation as a potential ...
Liam A. O'Callaghan   +3 more
wiley   +1 more source

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