Results 101 to 110 of about 27,544,016 (212)

Ancient convergent losses of Paraoxonase 1 yield potential risks for modern marine mammals

Science, 2018
Adaptive conflicts with the modern world Mammals evolved in terrestrial environments. Those that now live in the marine environment have had to adapt to the particular selective pressures that this environment imposes. Meyer et al.
Wynn K. Meyer, Jerrica Jamison, R. Richter, S. Woods, Raghavendran Partha, Amanda Kowalczyk, Clair Kronk, M. Chikina, R. Bonde, D. Crocker, Joseph Gaspard, J. Lanyon, J. Marsillach, C. Furlong, Nathan L. Clark   +14 more
semanticscholar   +1 more source

Decreased serum PON1 arylesterase activity in familial hypercholesterolemia patients with a mutated LDLR gene

Genetics and Molecular Biology, 2018
Paraoxonase 1 (PON1) is a serum enzyme associated with high density lipoprotein (HDL) regulation through its paraoxonase and arylesterase activity. PON1 inhibits the oxidation of HDL and low density lipoprotein (LDL), and is involved in the pathogenesis ...
Muhammad Idrees, Abdul Rauf Siddiq, Muhammad Ajmal, Muhammad Akram, Rana Rehan Khalid, Alamdar Hussain, Raheel Qamar, Habib Bokhari   +7 more
doaj   +1 more source

Mutual Influences between Nitric Oxide and Paraoxonase 1

Antioxidants, 2019
One of the best consolidated paradigms in vascular pharmacology is that an uncontrolled excess of oxidizing chemical species causes tissue damage and loss of function in the endothelial and subendothelial layers.
M. Marín, C. Moya, S. Máñez
semanticscholar   +1 more source

High Concentration of Medium-Sized HDL Particles and Enrichment in HDL Paraoxonase 1 Associate With Protection From Vascular Complications in People With Long-standing Type 1 Diabetes

Diabetes Care, 2019
OBJECTIVE A subset of people with long-standing type 1 diabetes (T1D) appears to be protected from microvascular and macrovascular complications. Previous studies have focused on improved abilities to respond to glucose and its downstream effects as ...
T. Vaisar, J. Kanter, Jake Wimberger, Angela D. Irwin, J. Gauthier, E. Wolfson, Vanessa Bahnam, I-Hsien Wu, Hetal S. Shah, H. Keenan, C. Greenbaum, G. King, J. Heinecke, K. Bornfeldt   +13 more
semanticscholar   +1 more source

The anti-inflammatory function of HDL is impaired in type 2 diabetes: role of hyperglycemia, paraoxonase-1 and low grade inflammation

Cardiovascular Diabetology, 2017
BackgroundFunctional properties of high density lipoproteins (HDL) are increasingly recognized to play a physiological role in atheroprotection.
S. Ebtehaj, E. Gruppen, Mojtaba Parvizi, U. Tietge, R. Dullaart   +4 more
semanticscholar   +1 more source

Investigation of PON1 activity and MDA levels in patients with epilepsy not receiving antiepileptic treatment

Neuropsychiatric Disease and Treatment, 2016
Nilüfer Dönmezdil, Mehmet Uğur Çevik, Hasan Hüseyin Özdemir, Muhterem Taşin Department of Neurology, Dicle University, Diyarbakır, Turkey Purpose: There are many studies dedicated to researching the ...
Dönmezdil N, Cevik MU, Ozdemir HH, Taşin M   +3 more
doaj  

Q192R paraoxonase gene 1 (PON1) polymorphism and atorvastatin therapy effect in patients with type 2 diabetes mellitus (T2DM)

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2015
Study objective: to estimate efficiency of atorvastatin therapy in patients with type 2 diabetes mellitus (T2DM), who are the carrier of various genotypes Q192R paraoxonase gene 1 (PON1).
M. V. Kim, S. A. Skoryukova, A. A. Bystrova, E. I. Baranova, S. N. Pchelina   +4 more
doaj   +1 more source

Paraoxonase 1 Activity, Polymorphism and Atherosclerosis Risk Factors in Patients Undergoing Coronary Artery Surgery

Journal of Clinical Medicine, 2019
Background: Paraoxonase1 (PON1), an enzyme connected to high density lipoproteins (HDL) particles, plays an important role in protecting arteries against atherosclerosis.
A. Wysocka, M. Cybulski, Andrzej P.Wysokiński, H. Berbeć, J. Stążka, T. Zapolski   +5 more
semanticscholar   +1 more source

Alterations in paraoxonase-1 activity

Bratislava Medical Journal, 2013
E, Yalcinkaya, B, Bugan, M, Celik, U C, Yuksel   +3 more
openaire   +3 more sources

Tetranectin and Paraoxonase-1 as Markers of Heart Failure. [PDF]

Medicina (Kaunas)
Vulciu PA, Valea NC, Zdremtan D, Alexandru C, Varga NI, Donath-Miklos I, Mot MD, Puschita M.   +7 more
europepmc   +1 more source