Results 51 to 60 of about 107,672,034 (158)

Paraoxonase-1 status in patients with hereditary hemochromatosis [PDF]

Journal of Lipid Research, 2013
Hereditary hemochromatosis (HH) is characterized by accumulation of iron, oxidative stress, inflammation, and fibrogenesis in liver tissue. In this setting, research on the protection afforded by intracellular antioxidants is of clinical relevance. Paraoxonase-1 (PON1) is an enzyme that degrades lipid peroxides.
MARTINELLI, Nicola, García Heredia A, Roca H, Aranda N, Arija V, Mackness B, Mackness M, BUSTI, Fabiana, Aragonès G, Pedro Botet J, PEDICA, Federica, CATALDO, Ivana, Marsillach J, Joven J, Girelli D, Camps J.   +15 more
openaire   +4 more sources

Paraoxonase 1 Activity in Endocrine Diseases

Endocrinology Research and Practice, 2011
Paraoxonase is an esterase bound to high-density lipoproteins which by metabolizing lipid peroxides, prevents their accumulation on low-density lipoproteins. It also hydrolyzes various organophosphorus compounds.
Özlem Tarçın, Dilek Gogas Yavuz
doaj   +2 more sources

Chronic, Environmentally Relevant PM2.5 Exposure Exacerbates Metabolic Dysfunction‐Associated Steatotic Liver Disease and Early‐Stage Renal Dysfunction in a Rodent Model

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 10, October 2026.
ABSTRACT While epidemiological studies link fine particulate matter (PM2.5) exposure to metabolic dysfunction‐associated steatotic liver disease (MASLD) and renal dysfunction, a translational gap exists, as most animal models utilize acute, high‐dose exposures that poorly reflect chronic, moderate‐level human scenarios.
Yi‐Siao Chen, Hugo You‐Hsien Lin, Chien‐Tzu Lin, Si‐Hua Huang, Ming‐Lun Yeh, Ming‐Lung Yu, Jin‐Ching Lee, Yao‐Chi Chung, Wei‐Ming Li, Ching‐Chia Li, Shiu‐Feng Huang, Chia‐Hung Yen   +11 more
wiley   +1 more source

Paraoxonase-1 activities in children and adolescents with type 1 diabetes mellitus [PDF]

, 2016
Background: Paraoxonase-1 is an HDL-associated esterase that acts as an anti-atherogenic agent by protecting LDL from oxidation. This study investigates paraoxonase-1 activities in children and adolescents with type 1 diabetes mellitus and possible ...
Cret, Victoria, Craciun, Elena, Rusu, Razvan, David, Bianca, Leucuta, Daniel, Dronca, Eleonora, Victoria Cret,, David, Bianca Andreea, Razvan L Rusu,, Eleonora Dronca,, Elena C Craciun,, Daniel C Leucuta,   +11 more
core   +1 more source

Serum Paraoxonase-1 Activity and Paraoxonase Q192 Gene Polymorphism in a Young, Healthy Population

Endocrinology Research and Practice, 2021
Objective: Paraoxonase-1 (PON1) enzyme and PON Q192R gene polymorphism are associated with atherosclerosis in many middle-aged individuals and high populations at risk of cardiovascular disease. This study aimed to determine serum PON-1 and arylesterase (
Dilek GOGAS YAVUZ, Özlem ÜSTAY, Palmet GÜN ATAK, Ahu TELLİ, Tuğçe APAYDIN, Önder ŞİRİKÇİ   +5 more
doaj   +1 more source

Seminal Extracellular Vesicles as Molecular Modulators of Male Reproductive Function

Reproduction in Domestic Animals, Volume 61, Issue S3, October 2026.
ABSTRACT Extracellular vesicles (sEVs) contained in seminal plasma (SP) maintain, in concert with free SP‐components (proteins, hormones, cytokines, metabolites and antioxidants) under an endocrine umbrella the functional in vivo homeostasis of ejaculated spermatozoa. The sEVs define a generic mixture of nanovesicles delivered by male epithelial cells,
Heriberto Rodriguez‐Martinez, Jordi Roca, Fernando Peña Vega, Emilio A. Martinez   +3 more
wiley   +1 more source

Paraoxonase 1 Phenotype and Paraoxonase Activity in Asthmatic Patients

Iranian Journal of Allergy, Asthma and Immunology, 2015
Oxidative stress is involved in the pathogenesis of asthma. Paraoxonase 1 (PON1) and arylesterase are esterase enzymes displaying antioxidant characteristics.
Nurhan Sarioglu, Adnan Adil Hismiogullari, Fuat Erel, Dudu Demir, Nahit Gencer   +4 more
doaj  

Environmental Pesticide Exposure in the Etiology of Pediatric Brain Tumors and Leukemia: A Scoping Review of Epidemiological Studies

International Journal of Cancer, Volume 159, Issue 6, Page 1360-1384, 15 September 2026.
ABSTRACT Pediatric cancer is a significant cause of morbidity and mortality in children. The etiologies of pediatric cancer are largely unknown, but environmental pesticide exposures are likely to contribute. Chronic low‐dose exposure to pesticide mixtures through drinking water is a growing concern in agricultural communities.
Grace N. VanDeSteeg, Alyssa R. Russum, Matthew R. Sandbulte, Eleanor G. Rogan, Martha G. Rhoades   +4 more
wiley   +1 more source

The Potential Importance of Paraoxonase-1 in Surgical Patients [PDF]

Journal of Investigative Surgery, 2019
In recent years, the understanding of surgical stress has been expanded due to increased research interest, mainly driven by the introduction of novel biomarkers and innovative surgical techniques....
Vekić, Jelena, Kotur-Stevuljević, Jelena   +1 more
openaire   +4 more sources

Relationship of paraoxonase-1 and paraoxonase-3 with routine laboratory tests and oxidative stress in type 2 diabetes mellitus

Türk Biyokimya Dergisi
We aimed to investigate the relationship between serum paraoxonase-1 (PON1) and paraoxonase-3 (PON3) levels and activities with hemoglobin A1c (HbA1c), serum fasting blood glucose, lipid profile, and oxidative stress in patients with type 2 diabetes ...
Ucar Yagcı Yagmur, Yılmaz Bulbul Buket, Sut Necdet, Ozgun Eray   +3 more
doaj   +1 more source