Results 51 to 60 of about 29,702,919 (206)

Alterações no metabolismo lipídico em pacientes HIV soropositivos [PDF]

, 2007
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em FarmáciaO HIV infecta e depleta os linfócitos T CD4, resultando em imunodeficiência e progressão da doença. Os pacientes infectados
Daminelli, Elaine Nunes
core  

Environmental Pesticide Exposure in the Etiology of Pediatric Brain Tumors and Leukemia: A Scoping Review of Epidemiological Studies

International Journal of Cancer, Volume 159, Issue 6, Page 1360-1384, 15 September 2026.
ABSTRACT Pediatric cancer is a significant cause of morbidity and mortality in children. The etiologies of pediatric cancer are largely unknown, but environmental pesticide exposures are likely to contribute. Chronic low‐dose exposure to pesticide mixtures through drinking water is a growing concern in agricultural communities.
Grace N. VanDeSteeg, Alyssa R. Russum, Matthew R. Sandbulte, Eleanor G. Rogan, Martha G. Rhoades   +4 more
wiley   +1 more source

Paraoxonase-1 status in patients with hereditary hemochromatosis [PDF]

Journal of Lipid Research, 2013
Hereditary hemochromatosis (HH) is characterized by accumulation of iron, oxidative stress, inflammation, and fibrogenesis in liver tissue. In this setting, research on the protection afforded by intracellular antioxidants is of clinical relevance. Paraoxonase-1 (PON1) is an enzyme that degrades lipid peroxides.
MARTINELLI, Nicola, García Heredia A, Roca H, Aranda N, Arija V, Mackness B, Mackness M, BUSTI, Fabiana, Aragonès G, Pedro Botet J, PEDICA, Federica, CATALDO, Ivana, Marsillach J, Joven J, Girelli D, Camps J.   +15 more
openaire   +4 more sources

Oral squamous cell carcinoma and serum paraoxonase 1

, 2013
Background: Serum paraoxonase 1 is involved in mechanisms that protect cells from oxidative stress damage. This study aimed to investigate the correlation between serum paraoxonase 1 activity and polymorphisms in patients with oral squamous cell ...
AYDIN, S., Isbir, T., Toptas, B., Metin, Z. Boy, Hafiz, G., Cakmakoglu, B., Unur, Meral   +6 more
core   +1 more source

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

Arthritis Care &Research, Volume 78, Issue 9, Page 1112-1122, September 2026.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah, Sangmee S. Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

The altered expression of Paraoxonase 1 in the gastric carcinoma.

, 2018
94 Background: High doses inadequate removal of reactive oxygen species result in oxidative stress, which may cause severe metabolic malfunctions and damage to biological molecules including DNA An elevated oxidative status has been found in many types
Jin Soo Kim, Sung Soo Kim
core   +1 more source

Cardiovascular disease incidence and cancer risk in two large European prospective cohorts

International Journal of Cancer, Volume 159, Issue 5, Page 1139-1152, 1 September 2026.
What's new? Cardiovascular disease (CVD) and cancer share risk factors and biological mechanisms, raising questions about potential associations between the two, particularly regarding CVD duration and cancer onset. Whether CVD influences subsequent cancer risk, however, remains inconclusive.
Emma Fontvieille, Vivian Viallon, Laia Peruchet‐Noray, Quan Gan, N. Charlotte Onland‐Moret, Yvonne Koop, Anne Tjønneland, Nicola Patricia Bondonno, Verena Katzke, Rudolf Kaaks, Matthias B. Schulze, Catarina Schiborn, Calogero Saieva, Vittorio Simeon, Claudia Agnoli, Rosario Tumino, Fulvio Ricceri, Leila Luján‐Barroso, Maria‐José Sánchez, Conchi Moreno‐Iribas, Konstantinos K. Tsilidis, Marc J. Gunter, Adam Butterworth, Elio Riboli, Heinz Freisling, Pietro Ferrari   +25 more
wiley   +1 more source

Paraoxonase 1 in patients with diabetes mellitus [PDF]

, 2015
Humana serumska paraoksonaza 1 (PON1) je protein molekularne mase 43 kDa čija je katalitička aktivnost hidroliza organofosfatnih estera, aromatskih estera karboksilnih kiselina i karbamata.
Knežević, Josip
core   +1 more source

Paraoxonase 1 Phenotype and Paraoxonase Activity in Asthmatic Patients

Iranian Journal of Allergy, Asthma and Immunology, 2015
Oxidative stress is involved in the pathogenesis of asthma. Paraoxonase 1 (PON1) and arylesterase are esterase enzymes displaying antioxidant characteristics.
Nurhan Sarioglu, Adnan Adil Hismiogullari, Fuat Erel, Dudu Demir, Nahit Gencer   +4 more
doaj  

Serum Paraoxonase-1 Activity and Paraoxonase Q192 Gene Polymorphism in a Young, Healthy Population

Endocrinology Research and Practice, 2021
Objective: Paraoxonase-1 (PON1) enzyme and PON Q192R gene polymorphism are associated with atherosclerosis in many middle-aged individuals and high populations at risk of cardiovascular disease. This study aimed to determine serum PON-1 and arylesterase (
Dilek GOGAS YAVUZ, Özlem ÜSTAY, Palmet GÜN ATAK, Ahu TELLİ, Tuğçe APAYDIN, Önder ŞİRİKÇİ   +5 more
doaj   +1 more source