Results 31 to 40 of about 107,672,034 (158)
Regulation of Hepatic Paraoxonase-1 Expression [PDF]
Journal of Lipids, 2012 Serum paraoxonase-1 (PON1) is a member of the paraoxonases family (PON1, PON2, and PON3). PON1 is synthesized and secreted by the liver, and in circulation it is associated with HDL. PON1 has antioxidative properties, which are associated with the enzyme’s capability to decrease oxidative stress in atherosclerotic lesions and to attenuate ...
openaire +2 more sources
Kinesiologia SlovenicaParaoxonase (PON) enzyme family (paraoxonase 1, 2 and 3) has antiatherosclerotic properties. The decreased PON1 enzyme activity (EA), PON1 level and PON1-L55M polymorphism (PON1P) are risk factors for atherosclerosis.
Ezgi Sevilmis +6 more
doaj +1 more source
Myeloperoxidase and paraoxonase-1 in type 2 diabetic patients
, 2009 BACKGROUND AND AIMS: Reduced high density lipoproteins (HDL) and increased oxidative stress are features of type 2 diabetes. Myeloperoxidase is an oxidative enzyme partly associated with HDL and causing HDL dysfunction.
Jornayvaz, François +5 more
core +1 more source
Advanced Science, EarlyView.A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou +12 more
wiley +1 more source
The paraoxonase 1, 2 and 3 in humans
Biochemia Medica, 2011 The paraoxonase gene family in humans includes three members: PON1, PON2 and PON3. The products of those three genes are the following enzymes: paraoxonase 1 (PON1), paraoxonase 2 (PON2) and paraoxonase 3 (PON3). PON1 is mainly associated with a high density lipoprotein (HDL). A small amount of this enzyme is also bound to very low-density lipoprotein (
Grdic Rajkovic, Marija +2 more
openaire +5 more sources
Induction of the Paraoxonase-1 Gene Expression by Resveratrol [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2004 Objective— The human paraoxonase-1 (PON-1) is a high-density lipoprotein-associated enzyme, mainly secreted by the liver, that displays protective properties toward cardiovascular disease and organophosphate intoxication.
Cédric, Gouédard +2 more
openaire +2 more sources
Advanced Science, EarlyView.Here, a PDL1 inhibitor is employed as a fifth component to modify lipid nanoparticles (LNPs). PDL1 inhibitor‐loaded LNPs show enhanced lymph node targeting, resulting in greater lymph node expansion, immune cell infiltration, and improved mRNA vaccine efficacy. This fifth component LNP could be a novel platform for mRNA vaccines.
Minki Ha +5 more
wiley +1 more source
Oral squamous cell carcinoma and serum paraoxonase 1
, 2013 Background: Serum paraoxonase 1 is involved in mechanisms that protect cells from oxidative stress damage. This study aimed to investigate the correlation between serum paraoxonase 1 activity and polymorphisms in patients with oral squamous cell ...
AYDIN, S. +6 more
core +1 more source
Human Paraoxonase-1 Activity in Children with Acute Bronchiolitis
, 2020 INTRODUCTION: Human paraoxonase-1 (PON1) is one of the endogenous antioxidant molecules working against oxidative stress.
ERENBERK U. +5 more
core +1 more source
Paraoxonase activity assessment in dogs suffering from Parvovirus infection [PDF]
, 2021 ΔΕΝ ΔΙΑΤΙΘΕΤΑΙ ΠΕΡΙΛΗΨΗCanine Parvovirus enteritis is one of the most common causes of diarrhea and death in dogs younger than 6 months of age. Clinical gastroenteritis in parvo-positive dogs is associated with increased levels of lipid peroxides and ...
SALARPOUR, R. +3 more
core