Results 31 to 40 of about 29,702,919 (206)

Study the levels of Leptin, and Adiponectin with Paraoxonase in Obese Individuals (male & female)

open access: yesTikrit Journal of Pure Science, 2023
Obesity is a well-known risk factor of metabolic complications and cardiovascular disease. Associations between anthropometric measurements and fat distribution and risk factors  for cardiovascular disease have been demonstrated in several populations.
Entedhar R. Sarhat
doaj   +1 more source

Paraoxonase 1 as an important antiatherogenic agent

open access: yesJournal of Education, Health and Sport, 2019
The inverse relationship between High Density Lipoproteins (HDL) level and risk of ischaemic heart disease was proved by many epidemiological studies. Although the main mechanism of antiatherogenic activity of HDL is a reverse transport of cholesterol ...
Ewa Lidia Krzewicka-Romaniuk   +3 more
doaj   +3 more sources

Regulation of Hepatic Paraoxonase-1 Expression [PDF]

open access: yesJournal of Lipids, 2012
Serum paraoxonase-1 (PON1) is a member of the paraoxonases family (PON1, PON2, and PON3). PON1 is synthesized and secreted by the liver, and in circulation it is associated with HDL. PON1 has antioxidative properties, which are associated with the enzyme’s capability to decrease oxidative stress in atherosclerotic lesions and to attenuate ...
openaire   +2 more sources

Paraoxonase and Paraoxon Detoxification (Pharmacokinetics).

open access: yes, 1984
Paraoxon is the toxic metabolite of the widely used organophosphorous insecticide, parathion. Human serum paraoxonase, an enzyme which hydrolyzes paraoxon to two non-toxic products, is polymorphically distributed.
Butler, Edward Grant
core   +5 more sources

Assessment of Serum Level of Paraoxonase-1 in Patients with Psoriasis Vulgaris [PDF]

open access: yes, 2022
Background: Psoriasis is a chronic inflammatory dermatological disease with a strong genetic predisposition and autoimmune pathogenic traits. The hallmark of psoriasis is sustained inflammation that leads to uncontrolled keratinocyte proliferation and ...
Abo-Elsood, Karima Hussein Mohamed   +3 more
core  

Beyond Biomimetics: Pathology‐Informed Engineering Rescues Reconstituted HDL From Inflammatory Dysfunction for Sepsis Immunotherapy

open access: yesAdvanced Science, EarlyView.
A pathology‐informed engineering strategy rescues reconstituted HDL from inflammatory dysfunction in sepsis. By integrating a ceria nanozyme‐celastrol coordination complex, the platform preserves HDL structure and endotoxin handling, sustains hierarchical intracellular delivery, and enhances immunoregulation across pathological models, translating ...
Han Zhou   +12 more
wiley   +1 more source

Induction of the Paraoxonase-1 Gene Expression by Resveratrol [PDF]

open access: yesArteriosclerosis, Thrombosis, and Vascular Biology, 2004
Objective— The human paraoxonase-1 (PON-1) is a high-density lipoprotein-associated enzyme, mainly secreted by the liver, that displays protective properties toward cardiovascular disease and organophosphate intoxication.
Cédric, Gouédard   +2 more
openaire   +2 more sources

Estudo dos polimorfismos PON1-192 e PON2-311 e atividade da enzima paroxonase em pacientes diabéticos tipo 2 [PDF]

open access: yes, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2004A paroxonase sérica humana (PON) é uma enzima localizada na HDL e está envolvida na detoxificação de ...
Catapan, Elisangela
core  

Decrease Paraoxonase-1 (PON-1) Activities in Neurodegenerative Diseases

open access: yes, 2016
Decrease Paraoxonase-1 (PON-1) Activities in Neurodegenerative ...
Cervellati, Carlo   +17 more
core   +1 more source

Evaluation of Lipid metabolizing enzymes: Paraxonase1(PON1) and Lecithin Cholesterol acyltransferase (LCAT) activities in children with nephrotic syndrome

open access: yesBaghdad Journal of Biochemistry and Applied Biological Sciences, 2021
Background: The most common glomerular disorder in children is nephrotic syndrome, associated with high morbidity despite notable advances in its treatment. Many of the nephrotic syndrome complications, including the increased risk of atherosclerosis and
Raghad Jamal Ali   +2 more
doaj  

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